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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma

Cell reports (Cambridge), 2023-03, Vol.42 (3), p.112197-112197, Article 112197

2023

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Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

BMC biology, 2023-04, Vol.21 (1), p.98-98, Article 98

2023

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Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization

Cellular oncology (Dordrecht), 2024-02, Vol.47 (1), p.259-282

2024

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Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution

Molecular therapy. Oncolytics, 2023-09, Vol.30, p.39-55

2023

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Trabectedin promotes oncolytic virus antitumor efficacy, viral gene expression, and immune effector function in models of bone sarcoma

Molecular Therapy: Oncology, 2024-12, Vol.32 (4), p.200886, Article 200886

2024

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Abstract PO-123: Distinct subpopulations of osteosarcoma cells cooperate to establish lung metastases

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (21_Supplement), p.PO-123-PO-123

2020

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Abstract PO-012: Metastatic bottleneck in osteosarcoma selects for certain clonal populations, while metastatic lesions exhibit diverse phenotypes

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (21_Supplement), p.PO-012-PO-012

2020

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GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma

International journal of cancer, 2020-06, Vol.146 (11), p.3184-3195

2020

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Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease

Oncotarget, 2020-02, Vol.11 (5), p.510-522

2020

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p53/TAp63 and AKT Regulate Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling through Two Independent Parallel Pathways in the Presence of DNA Damage

The Journal of biological chemistry, 2014-02, Vol.289 (7), p.4083-4094

2014

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Abstract 3179: Tumor educated lung epithelial cells promote osteosarcoma metastasis and chemotherapy resistance by inducing integrin dependent fibronectin fibrillogenesis

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3179-3179

2022

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Abstract 5456: Identifying the role of tissue factor in osteosarcoma metastasis

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5456-5456

2024

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ΔNp73/ETS2 complex drives glioblastoma pathogenesis— targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma

Neuro-oncology (Charlottesville, Va.), 2020-03, Vol.22 (3), p.345-356

2020

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ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis

Cancer research (Chicago, Ill.), 2014-01, Vol.74 (1), p.320-329

2014

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LGG-47. Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity During Malignant Progression in Glioma

Neuro-oncology (Charlottesville, Va.), 2022-06, Vol.24 (Supplement_1), p.i99-i99

2022

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Abstract 5516: Aberrant activation and perpetuation of lung wound response facilitates osteosarcoma metastasis

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5516-5516

2024

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Abstract 5457: Inflammatory paracrine loops established between metastasis-initiating cells and alveolar epithelium drive interactions between tumor cell subtypes that are essential for osteosarcoma lung colonization

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5457-5457

2024

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Abstract 2511: Metastatic lung colonization by osteosarcoma requires cooperation between tumor subpopulations with distinct phenotypes

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2511-2511

2022

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Abstract 801: Surprisingly conserved copy numbers from cell to cell within structurally complex tumors challenge the unstable genome hypothesis

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.801-801

2022

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Abstract 1087: Synergistic mechanisms against pediatric bone sarcoma models: Trabectedin enhances oncolytic virotherapy intratumoral spread and antitumor immune activation

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.1087-1087

2024

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IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis

JCI insight, 2018-08, Vol.3 (16)

2018

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Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time

Cancer research communications, 2023-04, Vol.3 (4), p.564-575

2023

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Abstract 2533: MAPK-driven MCL1 expression promotes osteosarcoma survival in the metastatic niche

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.2533-2533

2023

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Abstract 64: Tumor-tumor cooperation during osteosarcoma lung metastasis is driven by interactions between lung epithelia and niche-initiating anchor cells

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.64-64

2023

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ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

Oncotarget, 2016-07, Vol.7 (30), p.48533-48546

2016

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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization

Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution

Trabectedin promotes oncolytic virus antitumor efficacy, viral gene expression, and immune effector function in models of bone sarcoma

Abstract PO-123: Distinct subpopulations of osteosarcoma cells cooperate to establish lung metastases

Abstract PO-012: Metastatic bottleneck in osteosarcoma selects for certain clonal populations, while metastatic lesions exhibit diverse phenotypes

GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease

p53/TAp63 and AKT Regulate Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling through Two Independent Parallel Pathways in the Presence of DNA Damage

Abstract 3179: Tumor educated lung epithelial cells promote osteosarcoma metastasis and chemotherapy resistance by inducing integrin dependent fibronectin fibrillogenesis

Abstract 5456: Identifying the role of tissue factor in osteosarcoma metastasis

ΔNp73/ETS2 complex drives glioblastoma pathogenesis— targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma

ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis

LGG-47. Single-cell RNA Sequencing Reveals Immunosuppressive Myeloid Cell Diversity During Malignant Progression in Glioma

Abstract 5516: Aberrant activation and perpetuation of lung wound response facilitates osteosarcoma metastasis

Abstract 5457: Inflammatory paracrine loops established between metastasis-initiating cells and alveolar epithelium drive interactions between tumor cell subtypes that are essential for osteosarcoma lung colonization

Abstract 2511: Metastatic lung colonization by osteosarcoma requires cooperation between tumor subpopulations with distinct phenotypes

Abstract 801: Surprisingly conserved copy numbers from cell to cell within structurally complex tumors challenge the unstable genome hypothesis

Abstract 1087: Synergistic mechanisms against pediatric bone sarcoma models: Trabectedin enhances oncolytic virotherapy intratumoral spread and antitumor immune activation

IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis

Structurally Complex Osteosarcoma Genomes Exhibit Limited Heterogeneity within Individual Tumors and across Evolutionary Time

Abstract 2533: MAPK-driven MCL1 expression promotes osteosarcoma survival in the metastatic niche

Abstract 64: Tumor-tumor cooperation during osteosarcoma lung metastasis is driven by interactions between lung epithelia and niche-initiating anchor cells

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

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