UB Paderborn / Katalog / Suche / in CDI

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

Redox biology, 2020-01, Vol.28, p.101321-101321, Article 101321

2020

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Updating dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2): molecular basis, functions and role in diseases

Cellular and molecular life sciences : CMLS, 2020-12, Vol.77 (23), p.4747-4763

2020

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LUBAC determines chemotherapy resistance in squamous cell lung cancer

The Journal of experimental medicine, 2019-02, Vol.216 (2), p.450-465

2019

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Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis

Neurobiology of disease, 2020-09, Vol.143, p.104994-104994, Article 104994

2020

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EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis

Biochemical pharmacology, 2018-11, Vol.157, p.304-313

2018

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A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways

PLoS computational biology, 2021-02, Vol.17 (2), p.e1008748-e1008748

2021

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A cannabidiol aminoquinone derivative activates the PP2A/B55α/HIF pathway and shows protective effects in a murine model of traumatic brain injury

Journal of neuroinflammation, 2022-07, Vol.19 (1), p.1-177, Article 177

2022

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Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine

Biomedicine & pharmacotherapy, 2024-02, Vol.171, p.116149-116149, Article 116149

2024

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A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

Cell death and differentiation, 2022-01, Vol.29 (1), p.105-117

2022

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Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells

EMBO molecular medicine, 2020-04, Vol.12 (4), p.e11101-n/a

2020

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FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

Cell death & disease, 2023-03, Vol.14 (3), p.202-202, Article 202

2023

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USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K

Molecular oncology, 2022-09, Vol.16 (17), p.3082-3106

2022

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Metabolomic profiling of human lung tumor tissues – nucleotide metabolism as a candidate for therapeutic interventions and biomarkers

Molecular oncology, 2018-10, Vol.12 (10), p.1778-1796

2018

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Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy

Journal of neuroinflammation, 2018-03, Vol.15 (1), p.64-64, Article 64

2018

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Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery

Journal of translational medicine, 2023-12, Vol.21 (1), p.879-879, Article 879

2023

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An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response

Nature cell biology, 2009-01, Vol.11 (1), p.85-91

2009

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The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer

PloS one, 2015-11, Vol.10 (11), p.e0143376-e0143376

2015

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HIPK2, a Versatile Switchboard Regulating the Transcription Machinery and Cell Death

Cell cycle (Georgetown, Tex.), 2007-01, Vol.6 (2), p.139-143

2007

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Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions

Journal of biomedical science, 2024-01, Vol.31 (1), p.2-2, Article 2

2024

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Activation of latent HIV-1 expression by protein kinase C agonists. A novel therapeutic approach to eradicate HIV-1 reservoirs

Current drug targets, 2011-03, Vol.12 (3), p.348

2011

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Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (7), p.1705-1716

2012

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Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease

Frontiers in cell and developmental biology, 2021-03, Vol.9, p.641618-641618

2021

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Deep representation learning of tissue metabolome and computed tomography annotates NSCLC classification and prognosis

NPJ precision oncology, 2024-02, Vol.8 (1), p.28-28, Article 28

2024

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Phosphorylation-Dependent Control of Pc2 SUMO E3 Ligase Activity by Its Substrate Protein HIPK2

Molecular cell, 2006-10, Vol.24 (1), p.77-89

2006

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Control of nuclear HIPK2 localization and function by a SUMO interaction motif

Biochimica et biophysica acta, 2011-02, Vol.1813 (2), p.283-297

2011

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Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

Updating dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2): molecular basis, functions and role in diseases

LUBAC determines chemotherapy resistance in squamous cell lung cancer

Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis

EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis

A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways

A cannabidiol aminoquinone derivative activates the PP2A/B55α/HIF pathway and shows protective effects in a murine model of traumatic brain injury

Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine

A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival

Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K

Metabolomic profiling of human lung tumor tissues – nucleotide metabolism as a candidate for therapeutic interventions and biomarkers

Hypoxia mimetic activity of VCE-004.8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy

Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery

An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response

The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer

HIPK2, a Versatile Switchboard Regulating the Transcription Machinery and Cell Death

Localization, traffic and function of Rab34 in adipocyte lipid and endocrine functions

Activation of latent HIV-1 expression by protein kinase C agonists. A novel therapeutic approach to eradicate HIV-1 reservoirs

Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer

Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease

Deep representation learning of tissue metabolome and computed tomography annotates NSCLC classification and prognosis

Phosphorylation-Dependent Control of Pc2 SUMO E3 Ligase Activity by Its Substrate Protein HIPK2

Control of nuclear HIPK2 localization and function by a SUMO interaction motif

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