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MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

Nature communications, 2016-06, Vol.7 (1), p.12109-12109, Article 12109

2016

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A model‐based quantification of the impact of new manufacturing technologies on developing country vaccine supply chain performance: A Kenyan case study

Journal of advanced manufacturing and processing, 2019-07, Vol.1 (3), p.n/a

2019

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Agonist-specific voltage-dependent gating of lysosomal two-pore Na + channels

eLife, 2019-12, Vol.8

2019

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Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle

Developmental cell, 2017-05, Vol.41 (3), p.262-273.e6

2017

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Calibration of soil moisture sensing with subsurface heated fiber optics using numerical simulation

Water resources research, 2016-04, Vol.52 (4), p.2985-2995

2016

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Application of active heat pulse method with fiber optic temperature sensing for estimation of wetting bulbs and water distribution in drip emitters

Agricultural water management, 2013, Vol.120, p.72-78

2013

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Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.909-912

2005

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Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo

Molecular cancer therapeutics, 2006-01, Vol.5 (1), p.160-169

2006

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Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]‑1H‑benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep)

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3859-3874

2015

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Social life cycle assessment of green methanol and benchmarking against conventional fossil methanol

The Science of the total environment, 2022-06, Vol.824, p.153840-153840, Article 153840

2022

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Evaluación de la sostenibilidad de Bancos Comunitarios de Semillas Criollas de granos básicos en el Departamento de Matagalpa

Revista Iberoamericana de bioeconomía y cambio climàtico., 2023-12, Vol.9 (18), p.2173-2192

2023

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Discovery of vinylcycloalkyl-substituted benzimidazole TRPM8 antagonists effective in the treatment of cold allodynia

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.1903-1907

2012

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1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2–p53 interaction: discovery and SAR

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.765-770

2005

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Synthesis, Hirshfeld atom refinement of crystal structure, and Hirshfeld surface analysis of 5-ethoxycarbonyl-6-methyl-4-(2-(trifluoromethyl)phenyl)-3,4-dihydropyrimidin-2-(1H)-one formic acid monosolvate

Journal of molecular structure, 2023-11, Vol.1291, p.136068, Article 136068

2023

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Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction

iScience, 2022-09, Vol.25 (9), p.104941-104941, Article 104941

2022

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Operating within Planetary Boundaries without compromising well-being? A Data Envelopment Analysis approach

Journal of cleaner production, 2020-10, Vol.270, p.121833, Article 121833

2020

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Querying clinical data in HL7 RIM based relational model with morph-RDB

Journal of biomedical semantics, 2017-10, Vol.8 (1), p.49-49, Article 49

2017

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A deep learning approach using synthetic images for segmenting and estimating 3D orientation of nanoparticles in EM images

Computer methods and programs in biomedicine, 2021-04, Vol.202, p.105958-105958, Article 105958

2021

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Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3310-3314

2006

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Enabling semantic interoperability in multi-centric clinical trials on breast cancer

Computer methods and programs in biomedicine, 2015-03, Vol.118 (3), p.322-329

2015

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Estrategia organizacional del sector agropecuario de Nicaragua frente al cambio climático

Revista Iberoamericana de bioeconomía y cambio climàtico., 2023-06, Vol.9 (17), p.2090-2106

2023

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Discovery of piperidine carboxamide TRPV1 antagonists

Bioorganic & medicinal chemistry, 2008-08, Vol.18 (16), p.4569-4572

2008

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Substituted 1,4-Benzodiazepine-2,5-diones as α-Helix Mimetic Antagonists of the HDM2-p53 Protein-Protein Interaction

Chemical biology & drug design, 2006-03, Vol.67 (3), p.201-205

2006

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Enhancing vessel visibility in fundus images to aid the diagnosis of retinopathy of prematurity

Health informatics journal, 2020-12, Vol.26 (4), p.2722-2736

2020

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Quantitative Measures for Medical Fundus and Mammography Images Enhancement

International journal of interactive multimedia and artificial intelligence, 2023-12, Vol.8 (4), p.117

2023

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MCOLN1 is a ROS sensor in lysosomes that regulates autophagy

A model‐based quantification of the impact of new manufacturing technologies on developing country vaccine supply chain performance: A Kenyan case study

Agonist-specific voltage-dependent gating of lysosomal two-pore Na + channels

Gastric Acid Secretion from Parietal Cells Is Mediated by a Ca2+ Efflux Channel in the Tubulovesicle

Calibration of soil moisture sensing with subsurface heated fiber optics using numerical simulation

Application of active heat pulse method with fiber optic temperature sensing for estimation of wetting bulbs and water distribution in drip emitters

Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo

Benzo[d]imidazole Transient Receptor Potential Vanilloid 1 Antagonists for the Treatment of Pain: Discovery of trans-2-(2-{2-[2-(4-Trifluoromethyl-phenyl)-vinyl]‑1H‑benzimidazol-5-yl}-phenyl)-propan-2-ol (Mavatrep)

Social life cycle assessment of green methanol and benchmarking against conventional fossil methanol

Evaluación de la sostenibilidad de Bancos Comunitarios de Semillas Criollas de granos básicos en el Departamento de Matagalpa

Discovery of vinylcycloalkyl-substituted benzimidazole TRPM8 antagonists effective in the treatment of cold allodynia

1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2–p53 interaction: discovery and SAR

Synthesis, Hirshfeld atom refinement of crystal structure, and Hirshfeld surface analysis of 5-ethoxycarbonyl-6-methyl-4-(2-(trifluoromethyl)phenyl)-3,4-dihydropyrimidin-2-(1H)-one formic acid monosolvate

Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction

Operating within Planetary Boundaries without compromising well-being? A Data Envelopment Analysis approach

Querying clinical data in HL7 RIM based relational model with morph-RDB

A deep learning approach using synthetic images for segmenting and estimating 3D orientation of nanoparticles in EM images

Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design

Enabling semantic interoperability in multi-centric clinical trials on breast cancer

Estrategia organizacional del sector agropecuario de Nicaragua frente al cambio climático

Discovery of piperidine carboxamide TRPV1 antagonists

Substituted 1,4-Benzodiazepine-2,5-diones as α-Helix Mimetic Antagonists of the HDM2-p53 Protein-Protein Interaction

Enhancing vessel visibility in fundus images to aid the diagnosis of retinopathy of prematurity

Quantitative Measures for Medical Fundus and Mammography Images Enhancement

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