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API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing

Organic process research & development, 2021-06, Vol.25 (6), p.1284-1351

2021

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Development and Scale-Up of a Continuous, High-Pressure, Asymmetric Hydrogenation Reaction, Workup, and Isolation

Organic process research & development, 2012-05, Vol.16 (5), p.1017-1038

2012

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Continuous Liquid Vapor Reactions Part 2: Asymmetric Hydroformylation with Rhodium-Bisdiazaphos Catalysts in a Vertical Pipes-in-Series Reactor

Organic process research & development, 2016-05, Vol.20 (5), p.901-910

2016

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Continuous Liquid Vapor Reactions Part 1: Design and Characterization of a Reactor for Asymmetric Hydroformylation

Organic process research & development, 2016-05, Vol.20 (5), p.888-900

2016

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Rhodium-Catalyzed and Zinc(II)-Triflate-Promoted Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones

Organic letters, 2012-02, Vol.14 (4), p.1038-1041

2012

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Scalable Synthesis of Enantiopure Bis-3,4-diazaphospholane Ligands for Asymmetric Catalysis

Journal of organic chemistry, 2016-12, Vol.81 (23), p.11965-11970

2016

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Development of an NH4Cl-Catalyzed Ethoxy Ethyl Deprotection in Flow for the Synthesis of Merestinib

Organic process research & development, 2015-10, Vol.19 (10), p.1411-1417

2015

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Rapid Development and Scale-Up of a 1H-4-Substituted Imidazole Intermediate Enabled by Chemistry in Continuous Plug Flow Reactors

Organic process research & development, 2012-05, Vol.16 (5), p.982-1002

2012

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Development of a Stepwise Reductive Deoxygenation Process by Ru-Catalysed Homogeneous Ketone Reduction and Pd-Catalysed Hydrogenolysis in the Presence of Cu Salts

ChemCatChem, 2013-05, Vol.5 (5), p.1205-1210

2013

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A Selective Estrogen Receptor Modulator for the Treatment of Hot Flushes

Journal of medicinal chemistry, 2006-02, Vol.49 (3), p.843-846

2006

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Continuous GMP Manufacturing for Grignard Reagent/Zincate Synthesis and Negishi Coupling Reaction

Organic process research & development, 2024-05, Vol.28 (5), p.1734-1751

2024

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Rapid Development and Scale-Up of a 1 H -4-Substituted Imidazole Intermediate Enabled by Chemistry in Continuous Plug Flow Reactors

Organic process research & development, 2012-05, Vol.16 (5), p.982-1002

2012

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Development of an NH 4 Cl-Catalyzed Ethoxy Ethyl Deprotection in Flow for the Synthesis of Merestinib

Organic process research & development, 2015-10, Vol.19 (10), p.1411-1417

2015

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Efficient route to 3-methoxymethylquinolines – A precursor of 5-methoxymethylquinolinic acid

ARKIVOC, 2002-10, Vol.2002 (6), p.257-263

2002

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ChemInform Abstract: Rhodium-Catalyzed and Zinc(II) Triflate Promoted Asymmetric Hydrogenation of Tetrasubstituted [alpha],[beta]-Unsaturated Ketones

ChemInform, 2012-06, Vol.43 (26), p.no

2012

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ChemInform Abstract: Rhodium-Catalyzed and Zinc(II) Triflate Promoted Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones

ChemInform, 2012-06, Vol.43 (26), p.no-no

2012

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A Handmaid’s Tale: Amy Coney Barrett, originalism, and the specter of religion

Communication and Democracy, 2023-07, Vol.57 (2), p.153-177

2023

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An expanded universe of cancer targets

Cell, 2021-03, Vol.184 (5), p.1142-1155

2021

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Manipulating the 3D organization of the largest synthetic yeast chromosome

Molecular cell, 2023-12, Vol.83 (23), p.4424-4437.e5

2023

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"This is a patriotism check": Political economy, corruption, and duty to America in the 2020 primary debates

Argumentation and advocacy, 2021-10, Vol.57 (3-4), p.200-217

2021

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Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Nature communications, 2017-11, Vol.8 (1), p.1755-12, Article 1755

2017

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Benefits of greenhouse gas mitigation on the supply, management, and use of water resources in the United States

Climatic change, 2015-07, Vol.131 (1), p.127-141

2015

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A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy

AIDS (London), 2003-03, Vol.17 (5), p.691-698

2003

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Medial Open Transversus Abdominis Plane (MOTAP) Catheters Reduce Opioid Requirements and Improve Pain Control Following Open Liver Resection: A Multicenter, Blinded, Randomized Controlled Trial

Annals of surgery, 2018-08, Vol.268 (2), p.233-240

2018

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API Continuous Cooling and Antisolvent Crystallization for Kinetic Impurity Rejection in cGMP Manufacturing

Development and Scale-Up of a Continuous, High-Pressure, Asymmetric Hydrogenation Reaction, Workup, and Isolation

Continuous Liquid Vapor Reactions Part 2: Asymmetric Hydroformylation with Rhodium-Bisdiazaphos Catalysts in a Vertical Pipes-in-Series Reactor

Continuous Liquid Vapor Reactions Part 1: Design and Characterization of a Reactor for Asymmetric Hydroformylation

Rhodium-Catalyzed and Zinc(II)-Triflate-Promoted Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones

Scalable Synthesis of Enantiopure Bis-3,4-diazaphospholane Ligands for Asymmetric Catalysis

Development of an NH4Cl-Catalyzed Ethoxy Ethyl Deprotection in Flow for the Synthesis of Merestinib

Rapid Development and Scale-Up of a 1H-4-Substituted Imidazole Intermediate Enabled by Chemistry in Continuous Plug Flow Reactors

Development of a Stepwise Reductive Deoxygenation Process by Ru-Catalysed Homogeneous Ketone Reduction and Pd-Catalysed Hydrogenolysis in the Presence of Cu Salts

A Selective Estrogen Receptor Modulator for the Treatment of Hot Flushes

Continuous GMP Manufacturing for Grignard Reagent/Zincate Synthesis and Negishi Coupling Reaction

Kilogram-Scale GMP Manufacture of Tirzepatide Using a Hybrid SPPS/LPPS Approach with Continuous Manufacturing

Rapid Development and Scale-Up of a 1 H -4-Substituted Imidazole Intermediate Enabled by Chemistry in Continuous Plug Flow Reactors

Development of an NH 4 Cl-Catalyzed Ethoxy Ethyl Deprotection in Flow for the Synthesis of Merestinib

Efficient route to 3-methoxymethylquinolines – A precursor of 5-methoxymethylquinolinic acid

ChemInform Abstract: Rhodium-Catalyzed and Zinc(II) Triflate Promoted Asymmetric Hydrogenation of Tetrasubstituted [alpha],[beta]-Unsaturated Ketones

ChemInform Abstract: Rhodium-Catalyzed and Zinc(II) Triflate Promoted Asymmetric Hydrogenation of Tetrasubstituted α,β-Unsaturated Ketones

A Handmaid’s Tale: Amy Coney Barrett, originalism, and the specter of religion

An expanded universe of cancer targets

Manipulating the 3D organization of the largest synthetic yeast chromosome

"This is a patriotism check": Political economy, corruption, and duty to America in the 2020 primary debates

Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility

Benefits of greenhouse gas mitigation on the supply, management, and use of water resources in the United States

A phase II clinical study of the long-term safety and antiviral activity of enfuvirtide-based antiretroviral therapy

Medial Open Transversus Abdominis Plane (MOTAP) Catheters Reduce Opioid Requirements and Improve Pain Control Following Open Liver Resection: A Multicenter, Blinded, Randomized Controlled Trial

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