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Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic

British journal of anaesthesia : BJA, 2018-11, Vol.121 (5), p.1105-1114

2018

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Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2

PloS one, 2015-08, Vol.10 (8), p.e0132865-e0132865

2015

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Simultaneous targeting of multiple opioid receptors: a strategy to improve side-effect profile

British journal of anaesthesia : BJA, 2009-07, Vol.103 (1), p.38-49

2009

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In vitro pharmacological characterization of standard and new lysophosphatidic acid receptor antagonists using dynamic mass redistribution assay

Frontiers in pharmacology, 2023-11, Vol.14, p.1267414-1267414

2023

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Spinal antinociceptive effects of the novel NOP receptor agonist PWT2‐nociceptin/orphanin FQ in mice and monkeys

British journal of pharmacology, 2015-07, Vol.172 (14), p.3661-3670

2015

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Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test

Peptides (New York, N.Y. : 1980), 2017-08, Vol.94, p.71-77

2017

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In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives

British journal of pharmacology, 2014-09, Vol.171 (17), p.4138-4153

2014

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Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor

Neuropharmacology, 2012-04, Vol.62 (5-6), p.1999-2009

2012

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[tBu-d-Gly5]NPS, a pure and potent antagonist of the neuropeptide S receptor: In vitro and in vivo studies

Peptides (New York, N.Y. : 1980), 2012-04, Vol.34 (2), p.404-411

2012

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In vitro and in vivo pharmacological characterization of the synthetic opioid MT-45

Neuropharmacology, 2020-07, Vol.171, p.108110-108110, Article 108110

2020

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Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands

British journal of anaesthesia : BJA, 2015-04, Vol.114 (4), p.646-656

2015

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Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK‐21273 in comparison with SB‐612111

British journal of pharmacology, 2013-02, Vol.168 (4), p.863-879

2013

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A genomewide association study for average daily gain in Italian Large White pigs

Journal of animal science, 2014-04, Vol.92 (4), p.1385

2014

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Characterisation of dermorphinATTO488 at recombinant mu opioid peptide receptors

British journal of anaesthesia : BJA, 2020-04, Vol.124 (4), p.e206-e206

2020

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Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice

British journal of pharmacology, 2008-05, Vol.154 (2), p.471-479

2008

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Neuropeptide S produces hyperlocomotion and prevents oxidative stress damage in the mouse brain: A comparative study with amphetamine and diazepam

Pharmacology, biochemistry and behavior, 2009-02, Vol.91 (4), p.636-642

2009

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Pharmacology of nociceptin and its receptor: a novel therapeutic target

British journal of pharmacology, 2000-04, Vol.129 (7), p.1261-1283

2000

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Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands

Neuropharmacology, 2016-06, Vol.105, p.434-442

2016

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In vitro and in vivo characterization of the bifunctional μ and δ opioid receptor ligand UFP‐505

British journal of pharmacology, 2018-07, Vol.175 (14), p.2881-2896

2018

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[Dmt1]N/OFQ(1–13)‐NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist

British journal of pharmacology, 2013-01, Vol.168 (1), p.151-162

2013

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A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials

Scientific reports, 2017-04, Vol.7 (1), p.45780-45780, Article 45780

2017

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Neuropeptide S selectively inhibits the release of 5‐HT and noradrenaline from mouse frontal cortex nerve endings

British journal of pharmacology, 2009-06, Vol.157 (3), p.474-481

2009

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Functional nociceptin receptors are upregulated on human umbilical vein endothelial cells during experimental in vitro sepsis

British journal of anaesthesia : BJA, 2020-04, Vol.124 (4), p.e205-e206

2020

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Comparison of three patterns of feed supplementation with live Saccharomyces cerevisiae yeast on postweaning diarrhea, health status, and blood metabolic profile of susceptible weaning pigs orally challenged with Escherichia coli F4ac

Journal of animal science, 2015-05, Vol.93 (5), p.2225

2015

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A hierarchical modeling approach for clustering probability density functions

Computational statistics & data analysis, 2014-03, Vol.71, p.79-91

2014

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Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic

Pharmacological Profile of Nociceptin/Orphanin FQ Receptors Interacting with G-Proteins and β-Arrestins 2

Simultaneous targeting of multiple opioid receptors: a strategy to improve side-effect profile

In vitro pharmacological characterization of standard and new lysophosphatidic acid receptor antagonists using dynamic mass redistribution assay

Spinal antinociceptive effects of the novel NOP receptor agonist PWT2‐nociceptin/orphanin FQ in mice and monkeys

Antinociceptive action of NOP and opioid receptor agonists in the mouse orofacial formalin test

In vitro and in vivo pharmacological characterization of nociceptin/orphanin FQ tetrabranched derivatives

Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor

[tBu-d-Gly5]NPS, a pure and potent antagonist of the neuropeptide S receptor: In vitro and in vivo studies

In vitro and in vivo pharmacological characterization of the synthetic opioid MT-45

Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands

Acute and chronic antiparkinsonian effects of the novel nociceptin/orphanin FQ receptor antagonist NiK‐21273 in comparison with SB‐612111

A genomewide association study for average daily gain in Italian Large White pigs

Characterisation of dermorphinATTO488 at recombinant mu opioid peptide receptors

Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice

Neuropeptide S produces hyperlocomotion and prevents oxidative stress damage in the mouse brain: A comparative study with amphetamine and diazepam

Pharmacology of nociceptin and its receptor: a novel therapeutic target

Beta-arrestin 2 rather than G protein efficacy determines the anxiolytic-versus antidepressant-like effects of nociceptin/orphanin FQ receptor ligands

In vitro and in vivo characterization of the bifunctional μ and δ opioid receptor ligand UFP‐505

[Dmt1]N/OFQ(1–13)‐NH2: a potent nociceptin/orphanin FQ and opioid receptor universal agonist

A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials

Neuropeptide S selectively inhibits the release of 5‐HT and noradrenaline from mouse frontal cortex nerve endings

Functional nociceptin receptors are upregulated on human umbilical vein endothelial cells during experimental in vitro sepsis

Comparison of three patterns of feed supplementation with live Saccharomyces cerevisiae yeast on postweaning diarrhea, health status, and blood metabolic profile of susceptible weaning pigs orally challenged with Escherichia coli F4ac

A hierarchical modeling approach for clustering probability density functions

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