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Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects

Pharmacology, biochemistry and behavior, 2017-04, Vol.155, p.43-55

2017

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Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine

Neuropsychopharmacology (New York, N.Y.), 1996-02, Vol.14 (2), p.87-96

1996

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Olanzapine: a basic science update

British journal of psychiatry, 1999-02, Vol.174 (S37), p.36-40

1999

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In vitro and in vivo biochemistry of olanzapine: a novel, atypical antipsychotic drug

The journal of clinical psychiatry, 1997, Vol.58 Suppl 10, p.28

1997

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Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors

The Journal of pharmacology and experimental therapeutics, 1994-04, Vol.269 (1), p.271

1994

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Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

European journal of pharmacology, 2000-08, Vol.402 (3), p.241-246

2000

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Synthesis and Structure−Activity Relationships of Potent and Orally Active 5-HT4 Receptor Antagonists: Indazole and Benzimidazolone Derivatives

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1943-1955

1998

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Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects

Brain research, 1998-06, Vol.795 (1), p.179-190

1998

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Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5 R,6 R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane

European journal of pharmacology, 1998-09, Vol.356 (2), p.109-119

1998

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Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232)

The Journal of pharmacology and experimental therapeutics, 1994-04, Vol.269 (1), p.282

1994

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Central and peripheral cocaine receptors

The Journal of pharmacology and experimental therapeutics, 1987-10, Vol.243 (1), p.61

1987

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Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

Journal of medicinal chemistry, 1998-10, Vol.41 (22), p.4378-4384

1998

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3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex

Journal of medicinal chemistry, 1992-09, Vol.35 (18), p.3423-3425

1992

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Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats

Neuroreport, 1998-10, Vol.9 (15), p.3481-3486

1998

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Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract: Potential Application for the Treatment of Irritable Bowel Syndrome

Journal of medicinal chemistry, 1997-02, Vol.40 (4), p.538-546

1997

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Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones

Journal of medicinal chemistry, 1992-09, Vol.35 (18), p.3319-3324

1992

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High Affinity Stereospecific Binding of [3H] Cocaine in Striatum and its Relationship to the Dopamine Transporter

Membrane biochemistry, 1987, Vol.7 (2), p.87-106

1987

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Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine

Life sciences (1973), 1997-10, Vol.61 (21), p.2117-2126

1997

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The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine

The Journal of pharmacology and experimental therapeutics, 2000-08, Vol.294 (2), p.688

2000

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DL-Tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy

Journal of medicinal chemistry, 1992-11, Vol.35 (24), p.4608-4612

1992

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Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic M1 receptor activation

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2897-2902

1998

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A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data

International journal of geriatric psychiatry, 2001-12, Vol.16 (S1), p.S33-S61

2001

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Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats

The Journal of pharmacology and experimental therapeutics, 1999-08, Vol.290 (2), p.901

1999

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Preclinical studies on LY237733, a potent and selective serotonergic antagonist

The Journal of pharmacology and experimental therapeutics, 1992-01, Vol.260 (1), p.51

1992

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Pharmacological characterization of LY293284: A 5-HT1A receptor agonist with high potency and selectivity

The Journal of pharmacology and experimental therapeutics, 1994-09, Vol.270 (3), p.1270

1994

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Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects

Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine

Olanzapine: a basic science update

In vitro and in vivo biochemistry of olanzapine: a novel, atypical antipsychotic drug

Xanomeline: a novel muscarinic receptor agonist with functional selectivity for M1 receptors

Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice

Synthesis and Structure−Activity Relationships of Potent and Orally Active 5-HT4 Receptor Antagonists: Indazole and Benzimidazolone Derivatives

Xanomeline compared to other muscarinic agents on stimulation of phosphoinositide hydrolysis in vivo and other cholinomimetic effects

Unexpected antipsychotic-like activity with the muscarinic receptor ligand (5 R,6 R)6-(3-propylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane

Neurochemical effects of the M1 muscarinic agonist xanomeline (LY246708/NNC11-0232)

Central and peripheral cocaine receptors

Muscarinic Agonists with Antipsychotic-like Activity: Structure−Activity Relationships of 1,2,5-Thiadiazole Analogues with Functional Dopamine Antagonist Activity

3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex

Muscarinic agonists exhibit functional dopamine antagonism in unilaterally 6-OHDA lesioned rats

Muscarinic Analgesics with Potent and Selective Effects on the Gastrointestinal Tract: Potential Application for the Treatment of Irritable Bowel Syndrome

Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones

High Affinity Stereospecific Binding of [3H] Cocaine in Striatum and its Relationship to the Dopamine Transporter

Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brain penetration and activity in the neurogenic dural inflammation model of migraine

The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine

DL-Tetrazol-5-ylglycine, a highly potent NMDA agonist: its synthesis and NMDA receptor efficacy

Identification of side chains on 1,2,5-thiadiazole-azacycles optimal for muscarinic M1 receptor activation

A current review of olanzapine's safety in the geriatric patient: from pre-clinical pharmacology to clinical data

Muscarinic receptor agonists, like dopamine receptor antagonist antipsychotics, inhibit conditioned avoidance response in rats

Preclinical studies on LY237733, a potent and selective serotonergic antagonist

Pharmacological characterization of LY293284: A 5-HT1A receptor agonist with high potency and selectivity

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