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Critical pathogenic events underlying progression of neurodegeneration in glaucoma

Progress in retinal and eye research, 2012-11, Vol.31 (6), p.702-719

Calkins, David J.

2012

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The Microbead Occlusion Model: A Paradigm for Induced Ocular Hypertension in Rats and Mice

Investigative ophthalmology & visual science, 2010-01, Vol.51 (1), p.207-216

2010

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The Neurovascular Unit in Glaucomatous Neurodegeneration

Frontiers in cell and developmental biology, 2020-06, Vol.8, p.452-452

2020

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Adaptive responses to neurodegenerative stress in glaucoma

Progress in retinal and eye research, 2021-09, Vol.84, p.100953-100953, Article 100953

Calkins, David J.

2021

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α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction

PloS one, 2013-06, Vol.8 (6), p.e65389

2013

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Solving neurodegeneration: common mechanisms and strategies for new treatments

Molecular neurodegeneration, 2022-03, Vol.17 (1), p.23-23, Article 23

2022

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Distal axonopathy with structural persistence in glaucomatous neurodegeneration

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (11), p.5196-5201

2010

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Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection

The Journal of neuroscience, 2014-02, Vol.34 (9), p.3161-3170

2014

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Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration

Glia, 2014-09, Vol.62 (9), p.1435-1451

2014

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Early reduction of microglia activation by irradiation in a model of chronic glaucoma

PloS one, 2012-08, Vol.7 (8), p.e43602-e43602

2012

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Retinal astrocyte morphology predicts integration of vascular and neuronal architecture

Frontiers in neuroscience, 2023-08, Vol.17, p.1244679-1244679

2023

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Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension

Redox biology, 2021-06, Vol.42, p.101883-101883, Article 101883

2021

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Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of Glaucoma

The Journal of neuroscience, 2008-03, Vol.28 (11), p.2735-2744

2008

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Insulin Signaling as a Therapeutic Target in Glaucomatous Neurodegeneration

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4672

2021

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Optic neuropathy due to microbead-induced elevated intraocular pressure in the mouse

Investigative ophthalmology & visual science, 2011-01, Vol.52 (1), p.36-44

2011

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Collagen Mimetic Peptides Promote Repair of MMP-1-Damaged Collagen in the Rodent Sclera and Optic Nerve Head

International journal of molecular sciences, 2023-12, Vol.24 (23), p.17031

2023

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Collagen mimetic peptide repair of the corneal nerve bed in a mouse model of dry eye disease

Frontiers in neuroscience, 2023-05, Vol.17, p.1148950-1148950

2023

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Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma

Experimental eye research, 2016-09, Vol.150, p.34-43

2016

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Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy

Neurobiology of disease, 2013-11, Vol.59, p.26-37

2013

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Intraocular Delivery of a Collagen Mimetic Peptide Repairs Retinal Ganglion Cell Axons in Chronic and Acute Injury Models

International journal of molecular sciences, 2022-03, Vol.23 (6), p.2911

2022

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Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma

Scientific reports, 2020-05, Vol.10 (1), p.8535, Article 8535

2020

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Short-term increases in transient receptor potential vanilloid-1 mediate stress-induced enhancement of neuronal excitation

The Journal of neuroscience, 2014-11, Vol.34 (46), p.15369-15381

2014

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Collagen in the central nervous system: contributions to neurodegeneration and promise as a therapeutic target

Molecular neurodegeneration, 2024-01, Vol.19 (1), p.11-11, Article 11

2024

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Collagen Mimetic Peptides Promote Adherence and Migration of ARPE-19 Cells While Reducing Inflammatory and Oxidative Stress

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7004

2022

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Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration

The Journal of neuroscience, 2010-04, Vol.30 (16), p.5644-5652

2010

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Critical pathogenic events underlying progression of neurodegeneration in glaucoma

The Microbead Occlusion Model: A Paradigm for Induced Ocular Hypertension in Rats and Mice

The Neurovascular Unit in Glaucomatous Neurodegeneration

Adaptive responses to neurodegenerative stress in glaucoma

α-Lipoic acid antioxidant treatment limits glaucoma-related retinal ganglion cell death and dysfunction

Solving neurodegeneration: common mechanisms and strategies for new treatments

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection

Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration

Early reduction of microglia activation by irradiation in a model of chronic glaucoma

Retinal astrocyte morphology predicts integration of vascular and neuronal architecture

Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension

Progressive Ganglion Cell Degeneration Precedes Neuronal Loss in a Mouse Model of Glaucoma

Insulin Signaling as a Therapeutic Target in Glaucomatous Neurodegeneration

Optic neuropathy due to microbead-induced elevated intraocular pressure in the mouse

Collagen Mimetic Peptides Promote Repair of MMP-1-Damaged Collagen in the Rodent Sclera and Optic Nerve Head

Collagen mimetic peptide repair of the corneal nerve bed in a mouse model of dry eye disease

Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma

Proximal inhibition of p38 MAPK stress signaling prevents distal axonopathy

Intraocular Delivery of a Collagen Mimetic Peptide Repairs Retinal Ganglion Cell Axons in Chronic and Acute Injury Models

Of Mice and Monkeys: Neuroprotective Efficacy of the p38 Inhibitor BIRB 796 Depends on Model Duration in Experimental Glaucoma

Short-term increases in transient receptor potential vanilloid-1 mediate stress-induced enhancement of neuronal excitation

Collagen in the central nervous system: contributions to neurodegeneration and promise as a therapeutic target

Collagen Mimetic Peptides Promote Adherence and Migration of ARPE-19 Cells While Reducing Inflammatory and Oxidative Stress

Metabolic vulnerability disposes retinal ganglion cell axons to dysfunction in a model of glaucomatous degeneration

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