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Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer

Annals of surgical oncology, 2021-03, Vol.28 (3), p.1832-1844

2021

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Glycoprotein Receptor CEACAM5-Targeted Intraoperative Molecular Imaging Tracer in Non-Small Cell Lung Cancer

The Annals of thoracic surgery, 2023-09, Vol.116 (3), p.631-641

2023

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Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent

Annals of surgical oncology, 2018-10, Vol.25 (11), p.3350-3357

2018

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SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery

Surgical oncology, 2017-06, Vol.26 (2), p.153-162

2017

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Proof of concept of improved fluorescence-guided surgery of colon cancer liver metastasis using color-coded imaging of a tumor-labeling fluorescent antibody and indocyanine green restricted to the adjacent liver segment

Surgery, 2022-10, Vol.172 (4), p.1156-1163

2022

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Intraoperative molecular imaging of colorectal lung metastases with SGM-101: a feasibility study

European journal of nuclear medicine and molecular imaging, 2024-08, Vol.51 (10), p.2970-2979

2024

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Intraoperative detection of colorectal and pancreatic liver metastases using SGM-101, a fluorescent antibody targeting CEA

European journal of surgical oncology, 2021-03, Vol.47 (3), p.667-673

2021

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Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients

Toxicology reports, 2019-01, Vol.6, p.409-415

2019

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Carcinoembryonic Antigen-Related Cell Adhesion Molecule Type 5 Receptor-Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer: A Nonrandomized Controlled Trial

JAMA network open, 2023-01, Vol.6 (1), p.e2252885-e2252885

2023

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Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules

Biochemical journal, 2005-09, Vol.390 (Pt 2), p.407-418

2005

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Chemotrap-1: An Engineered Soluble Receptor That Blocks Chemokine-Induced Migration of Metastatic Cancer Cells In vivo

Cancer research (Chicago, Ill.), 2010-10, Vol.70 (20), p.8138-8148

2010

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Antibodies, tools of choice for fluorescence-guided surgery

M.S. Médecine sciences, 2020-01, Vol.35 (12), p.1066

2020

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Multimodal CEA-Targeted Image-Guided Colorectal Cancer Surgery using 111In-Labeled SGM-101

Clinical cancer research, 2020-11, Vol.26 (22), p.5934-5942

2020

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Les anticorps, outils de choix pour la chirurgie guidée par fluorescence

M.S. Médecine sciences, 2019-12, Vol.35 (12), p.1066-1071

2019

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Spectrally Distinct Double Labeling of Colon-Cancer Liver Metastases and Adjacent Liver Segment with a Near-Infrared-labeled Anti-Carcinoembryonic Antigen (CEA) Antibody and Indocyanine Green in an Orthotopic Mouse Model

Journal of the American College of Surgeons, 2021-11, Vol.233 (5), p.S154

2021

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NIR fluorochrome labeled anti-carcinoembryonic antigen monoclonal antibody for gastric cancer-specific image guided surgery

Journal of clinical oncology, 2022-02, Vol.40 (4_suppl), p.340-340

2022

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Improved Therapeutic Efficacy of Doxorubicin through Conjugation with a Novel Peptide Drug Delivery Technology (Vectocell)

Journal of medicinal chemistry, 2006-11, Vol.49 (23), p.6908-6916

2006

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Carcinoembryonic Antigen–Related Cell Adhesion Molecule Type 5 Receptor–Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer

JAMA network open, 2023-01, Vol.6 (1)

2023

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Multimodal CEA-Targeted Image-Guided Colorectal Cancer Surgery using 111 In-Labeled SGM-101

Clinical cancer research, 2020-11, Vol.26 (22), p.5934

2020

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The N-terminal segment of endothelin-converting enzyme (ECE)-1b contains a di-leucine motif that can redirect neprilysin to an intracellular compartment in Madin-Darby canine kidney (MDCK) cells

Biochemical journal, 1999-07, Vol.341 ( Pt 1) (1), p.119-126

1999

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The N-terminal segment of endothelin-converting enzyme (ECE)-1b contains a di-leucine motif that can redirect neprilysin to an intracellular compartment in Madin–Darby canine kidney (MDCK) cells

Biochemical journal, 1999-07, Vol.341 (1), p.119-126

1999

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Role of the glycosyl-phosphatidylinositol anchor in the intracellular transport of a transmembrane protein in Madin-Darby canine kidney cells

Biochimica et biophysica acta, 1998-12, Vol.1415 (1), p.1-9

1998

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The addition of a glycosyl-phosphatidylinositol-anchor to a soluble form of neutral endopeptidase re-establishes its apical targeting in LLC-PK1 cells

Biochemical Society transactions, 1996-05, Vol.24 (2), p.185S-185S

1996

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Role of the glycosyl-phosphatidylinositol anchor in membrane protein sorting in Madin-Darby canine kidney cells

Biochemical Society transactions, 1996-05, Vol.24 (2), p.186S-186S

1996

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Dose-Finding Study of a CEA-Targeting Agent, SGM-101, for Intraoperative Fluorescence Imaging of Colorectal Cancer

Glycoprotein Receptor CEACAM5-Targeted Intraoperative Molecular Imaging Tracer in Non-Small Cell Lung Cancer

Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent

SGM-101: An innovative near-infrared dye-antibody conjugate that targets CEA for fluorescence-guided surgery

Proof of concept of improved fluorescence-guided surgery of colon cancer liver metastasis using color-coded imaging of a tumor-labeling fluorescent antibody and indocyanine green restricted to the adjacent liver segment

Intraoperative molecular imaging of colorectal lung metastases with SGM-101: a feasibility study

Intraoperative detection of colorectal and pancreatic liver metastases using SGM-101, a fluorescent antibody targeting CEA

Toxicity and pharmacokinetic profile of SGM-101, a fluorescent anti-CEA chimeric antibody for fluorescence imaging of tumors in patients

Carcinoembryonic Antigen-Related Cell Adhesion Molecule Type 5 Receptor-Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer: A Nonrandomized Controlled Trial

Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules

Chemotrap-1: An Engineered Soluble Receptor That Blocks Chemokine-Induced Migration of Metastatic Cancer Cells In vivo

Antibodies, tools of choice for fluorescence-guided surgery

Multimodal CEA-Targeted Image-Guided Colorectal Cancer Surgery using 111In-Labeled SGM-101

Les anticorps, outils de choix pour la chirurgie guidée par fluorescence

Spectrally Distinct Double Labeling of Colon-Cancer Liver Metastases and Adjacent Liver Segment with a Near-Infrared-labeled Anti-Carcinoembryonic Antigen (CEA) Antibody and Indocyanine Green in an Orthotopic Mouse Model

NIR fluorochrome labeled anti-carcinoembryonic antigen monoclonal antibody for gastric cancer-specific image guided surgery

Improved Therapeutic Efficacy of Doxorubicin through Conjugation with a Novel Peptide Drug Delivery Technology (Vectocell)

Carcinoembryonic Antigen–Related Cell Adhesion Molecule Type 5 Receptor–Targeted Fluorescent Intraoperative Molecular Imaging Tracer for Lung Cancer

Multimodal CEA-Targeted Image-Guided Colorectal Cancer Surgery using 111 In-Labeled SGM-101

Safety and effectiveness of SGM-101, a fluorescent antibody targeting carcinoembryonic antigen, for intraoperative detection of colorectal cancer: a dose-escalation pilot study

The N-terminal segment of endothelin-converting enzyme (ECE)-1b contains a di-leucine motif that can redirect neprilysin to an intracellular compartment in Madin-Darby canine kidney (MDCK) cells

The N-terminal segment of endothelin-converting enzyme (ECE)-1b contains a di-leucine motif that can redirect neprilysin to an intracellular compartment in Madin–Darby canine kidney (MDCK) cells

Role of the glycosyl-phosphatidylinositol anchor in the intracellular transport of a transmembrane protein in Madin-Darby canine kidney cells

The addition of a glycosyl-phosphatidylinositol-anchor to a soluble form of neutral endopeptidase re-establishes its apical targeting in LLC-PK1 cells

Role of the glycosyl-phosphatidylinositol anchor in membrane protein sorting in Madin-Darby canine kidney cells

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