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Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

Investigational new drugs, 2014-10, Vol.32 (5), p.825-837

2014

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Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts

Clinical cancer research, 2014-07, Vol.20 (14), p.3763-3774

2014

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ERK Inhibitor LY3214996 Targets ERK Pathway-Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Molecular cancer therapeutics, 2020-02, Vol.19 (2), p.325-336

2020

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Abstract 5225: Temporal inhibition of ERK is sufficient for tumor growth inhibition in KRAS -mutant or BRAF -mutant tumors

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5225-5225

2020

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Abstract 4973: Discovery of LY3214996, a selective and novel ERK1/2 inhibitor with potent antitumor activities in cancer models with MAPK pathway alterations

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4973-4973

2017

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Abstract 3231: Identifying high quality, potent and selective pyrimidinylthienopyrrolone inhibitors of ERK1/2 kinase: LY3214996

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.3231-3231

2017

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Abstract B233: Identification and characterization of LY2835219: A potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) with broad in vivo antitumor activity

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.B233-B233

2011

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Effects of Halothane and Isoflurane on Bradykinin-evoked Calcium2+Influx in Bovine Aortic Endothelial Cells

Anesthesiology (Philadelphia), 1996-08, Vol.85 (2), p.366-679

1996

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Analysis of the outward currents induced by metabolic inhibition

Cai, Shufen

1993

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Partial contribution of the ATP-sensitive K+ current to the effects of mild metabolic depression in rabbit myocardium

Molecular and cellular biochemistry, 1994-03, Vol.132 (2), p.133-143

1994

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Localization and characterization of nitric oxide synthase at the frog neuromuscular junction

Journal of neurocytology, 1998-11, Vol.27 (11), p.829-840

1998

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Long‐Term Trajectory of Nitrogen Loading and Delivery From Mississippi River Basin to the Gulf of Mexico

Global biogeochemical cycles, 2020-05, Vol.34 (5), p.n/a

2020

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DNA nanosensor based on bipedal 3D DNA walker–driven proximal catalytic hairpin assembly for sensitive and fast TK1 mRNA detection

Mikrochimica acta (1966), 2024-08, Vol.191 (8), p.494, Article 494

2024

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Bilayer Wood Membrane with Aligned Ion Nanochannels for Spontaneous Moist-Electric Generation

Nano letters, 2022-08, Vol.22 (16), p.6476-6483

2022

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pH-activated DNA nanomachine for miRNA-21 imaging to accurately identify cancer cell

Mikrochimica acta (1966), 2022-07, Vol.189 (7), p.266-266, Article 266

2022

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Engineering of catalytic hairpin-rigidified Y-shaped DNA-functionalized nanomachine to rapidly detect mRNA

Mikrochimica acta (1966), 2023-06, Vol.190 (6), p.210-210, Article 210

2023

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pH-responsive DNA hydrogels with ratiometric fluorescence for accurate detection of miRNA-21

Analytica chimica acta, 2022-05, Vol.1207, p.339795-339795, Article 339795

2022

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Smartphone imaging spectrometer for egg/meat freshness monitoring

Analytical methods, 2022-02, Vol.14 (5), p.58-517

2022

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Effects of Carbon Nanotubes on Mechanical Strength, Damage Process, and Microstructure of Lithium Tailing Backfilling

Materials, 2024-08, Vol.17 (16), p.3885

2024

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Nlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates

Nature communications, 2024-01, Vol.15 (1), p.226-226, Article 226

2024

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Construction of an autofluorescence interference-free phosphorescence biosensor for the specific detection of TK1 mRNA

Analytica chimica acta, 2024-05, Vol.1303, p.342508-342508, Article 342508

2024

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Synthesis and characterization of biodegradable and photocrosslinkable multi‐block poly(ether‐ester): Molecular‐weight and component of the polyethylene glycol segment dependence

Journal of applied polymer science, 2023-12, Vol.140 (47)

2023

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Photopatternable and Highly Conductive PEDOT:PSS Electrodes for Flexible Perovskite Light-Emitting Diodes

ACS applied materials & interfaces, 2023-05, Vol.15 (17), p.21344-21353

2023

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Rapid generation of tomato male-sterile lines with a marker use for hybrid seed production by CRISPR/Cas9 system

Molecular breeding, 2021-03, Vol.41 (3), p.25-25, Article 25

2021

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Metabolic reprogramming-based characterization of circulating tumor cells in prostate cancer

Journal of experimental & clinical cancer research, 2018-06, Vol.37 (1), p.127-127, Article 127

2018

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Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

Semi-Mechanistic Pharmacokinetic/Pharmacodynamic Modeling of the Antitumor Activity of LY2835219, a New Cyclin-Dependent Kinase 4/6 Inhibitor, in Mice Bearing Human Tumor Xenografts

ERK Inhibitor LY3214996 Targets ERK Pathway-Driven Cancers: A Therapeutic Approach Toward Precision Medicine

Abstract 5225: Temporal inhibition of ERK is sufficient for tumor growth inhibition in KRAS -mutant or BRAF -mutant tumors

Abstract 4973: Discovery of LY3214996, a selective and novel ERK1/2 inhibitor with potent antitumor activities in cancer models with MAPK pathway alterations

Abstract 3231: Identifying high quality, potent and selective pyrimidinylthienopyrrolone inhibitors of ERK1/2 kinase: LY3214996

Abstract B233: Identification and characterization of LY2835219: A potent oral inhibitor of the cyclin-dependent kinases 4 and 6 (CDK4/6) with broad in vivo antitumor activity

Effects of Halothane and Isoflurane on Bradykinin-evoked Calcium2+Influx in Bovine Aortic Endothelial Cells

Analysis of the outward currents induced by metabolic inhibition

Partial contribution of the ATP-sensitive K+ current to the effects of mild metabolic depression in rabbit myocardium

Localization and characterization of nitric oxide synthase at the frog neuromuscular junction

Long‐Term Trajectory of Nitrogen Loading and Delivery From Mississippi River Basin to the Gulf of Mexico

DNA nanosensor based on bipedal 3D DNA walker–driven proximal catalytic hairpin assembly for sensitive and fast TK1 mRNA detection

Bilayer Wood Membrane with Aligned Ion Nanochannels for Spontaneous Moist-Electric Generation

pH-activated DNA nanomachine for miRNA-21 imaging to accurately identify cancer cell

Engineering of catalytic hairpin-rigidified Y-shaped DNA-functionalized nanomachine to rapidly detect mRNA

pH-responsive DNA hydrogels with ratiometric fluorescence for accurate detection of miRNA-21

Smartphone imaging spectrometer for egg/meat freshness monitoring

Effects of Carbon Nanotubes on Mechanical Strength, Damage Process, and Microstructure of Lithium Tailing Backfilling

Nlrc3 signaling is indispensable for hematopoietic stem cell emergence via Notch signaling in vertebrates

Construction of an autofluorescence interference-free phosphorescence biosensor for the specific detection of TK1 mRNA

Synthesis and characterization of biodegradable and photocrosslinkable multi‐block poly(ether‐ester): Molecular‐weight and component of the polyethylene glycol segment dependence

Photopatternable and Highly Conductive PEDOT:PSS Electrodes for Flexible Perovskite Light-Emitting Diodes

Rapid generation of tomato male-sterile lines with a marker use for hybrid seed production by CRISPR/Cas9 system

Metabolic reprogramming-based characterization of circulating tumor cells in prostate cancer

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