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Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

Trends in neurosciences (Regular ed.), 2017-03, Vol.40 (3), p.151-166

2017

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Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease

Nature neuroscience, 2019-03, Vol.22 (3), p.401-412

2019

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Neurovascular dysfunction in dementia - human cellular models and molecular mechanisms

Clinical science (1979), 2018-02, Vol.132 (3), p.399-418

2018

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Aneuploidy effects on human gene expression across three cell types

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (21), p.e2218478120-e2218478120

2023

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A causal role for TRESK loss of function in migraine mechanisms

Brain (London, England : 1878), 2019-12, Vol.142 (12), p.3852-3867

2019

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HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease

Brain (London, England : 1878), 2018-03, Vol.141 (3), p.673-687

2018

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A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

Stem cell reports, 2017-06, Vol.8 (6), p.1727-1742

2017

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TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses

Nature communications, 2020-09, Vol.11 (1), p.4614-4614, Article 4614

2020

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Rare variants in the CYP27B1 gene are associated with multiple sclerosis

Annals of neurology, 2011-12, Vol.70 (6), p.881-886

2011

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Altered neurochemical coupling in the occipital cortex in migraine with visual aura

Cephalalgia, 2015-10, Vol.35 (11), p.1025-1030

2015

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The molecular pathogenesis of migraine: new developments and opportunities

Human molecular genetics, 2013-10, Vol.22 (R1), p.R39-R44

Zameel Cader, M

2013

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Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Nature structural & molecular biology, 2012-12, Vol.19 (12), p.1293-1299

2012

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Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories

Genome research, 2021-06, Vol.31 (6), p.1069-1081

2021

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Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

Human molecular genetics, 2016-03, Vol.25 (5), p.989-1000

2016

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Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model

Brain (London, England : 1878), 2013-10, Vol.136 (10), p.3106-3118

2013

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Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model

Brain (London, England : 1878), 2013-10, Vol.136 (10), p.3106-3118

2013

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Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder

Molecular psychiatry, 2021-09, Vol.26 (9), p.5252-5265

2021

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Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles

Journal of neuroscience methods, 2014-04, Vol.227, p.159-165

2014

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From Young to Old: Mimicking Neuronal Aging in Directly Converted Neurons from Young Donors

Cells (Basel, Switzerland), 2024-08, Vol.13 (15), p.1260

2024

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Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models

Disease models & mechanisms, 2022-10, Vol.15 (10)

2022

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EBNA2 binds to genomic intervals associated with multiple sclerosis and overlaps with vitamin D receptor occupancy

PloS one, 2015-04, Vol.10 (4), p.e0119605-e0119605

2015

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Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy

Frontiers in molecular neuroscience, 2018-02, Vol.11, p.55

2018

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Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain

Human molecular genetics, 2017-01, Vol.26 (1), p.79-89

2017

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Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s disease

Stem cell research & therapy, 2024-07, Vol.15 (1), p.200-20, Article 200

2024

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Common transcriptional signatures of neuropathic pain

Pain (Amsterdam), 2020-07, Vol.161 (7), p.1542-1554

2020

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Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease

Neurovascular dysfunction in dementia - human cellular models and molecular mechanisms

Aneuploidy effects on human gene expression across three cell types

A causal role for TRESK loss of function in migraine mechanisms

HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease

A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses

Rare variants in the CYP27B1 gene are associated with multiple sclerosis

Altered neurochemical coupling in the occipital cortex in migraine with visual aura

The molecular pathogenesis of migraine: new developments and opportunities

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories

Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics

Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model

Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model

Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder

Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles

From Young to Old: Mimicking Neuronal Aging in Directly Converted Neurons from Young Donors

Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models

EBNA2 binds to genomic intervals associated with multiple sclerosis and overlaps with vitamin D receptor occupancy

Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy

Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain

Comprehensive characterization of the neurogenic and neuroprotective action of a novel TrkB agonist using mouse and human stem cell models of Alzheimer’s disease

Common transcriptional signatures of neuropathic pain

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