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Safety and Pharmacokinetics of Atypical Antipsychotics in Children and Adolescents

Paediatric drugs, 2013-06, Vol.15 (3), p.217-233

Caccia, Silvio

2013

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N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed

Current drug metabolism, 2007-08, Vol.8 (6), p.612

Caccia, Silvio

2007

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Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-07, Vol.791 (1), p.337-343

2003

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LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

Neuroscience letters, 2010-08, Vol.481 (1), p.12-16

2010

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A new generation of antipsychotics: pharmacology and clinical utility of cariprazine in schizophrenia

Therapeutics and clinical risk management, 2013-01, Vol.9 (default), p.319-328

2013

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Genotype-Dependent Activity of Tryptophan Hydroxylase-2 Determines the Response to Citalopram in a Mouse Model of Depression

The Journal of neuroscience, 2005-09, Vol.25 (36), p.8165-8172

2005

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Liquid chromatography–tandem mass spectrometry of I3,II8-biapigenin, the major biflavone in Hypericum perforatum extracts

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-02, Vol.863 (1), p.74-79

2008

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St. John's wort components and the brain: uptake, concentrations reached and the mechanisms underlying pharmacological effects

Current drug metabolism, 2009-11, Vol.10 (9), p.1055

2009

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Limbic Seizures Induce P-Glycoprotein in Rodent Brain: Functional Implications for Pharmacoresistance

The Journal of neuroscience, 2002-07, Vol.22 (14), p.5833-5839

2002

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Optimization of 4‑Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure–Activity Relationships, in Vivo Studies, and Preliminary Toxicity Profiling

Journal of medicinal chemistry, 2012-08, Vol.55 (15), p.6948-6967

2012

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Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils

Organic & biomolecular chemistry, 2011, Vol.9 (14), p.5137

2011

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Pharmacokinetics and metabolism update for some recent antipsychotics

Expert opinion on drug metabolism & toxicology, 2011-07, Vol.7 (7), p.829-846

Caccia, Silvio

2011

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New atypical antipsychotics for schizophrenia: iloperidone

Drug design, development and therapy, 2010-02, Vol.4 (default), p.33-48

2010

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A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10

PloS one, 2013-07, Vol.8 (7), p.e69540-e69540

2013

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Antidepressant-like components of Hypericum perforatum extracts: an overview of their pharmacokinetics and metabolism

Current drug metabolism, 2005-12, Vol.6 (6), p.531

Caccia, Silvio

2005

Volltextzugriff (PDF)

A Pilot Study on Brain‐to‐Plasma Partition of 10,11‐Dyhydro‐10‐hydroxy‐5H‐dibenzo(b,f)azepine‐5‐carboxamide and MDR1 Brain Expression in Epilepsy Patients Not Responding to Oxcarbazepine

Epilepsia (Copenhagen), 2005-10, Vol.46 (10), p.1613-1619

2005

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Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development

Neurobiology of disease, 2006-12, Vol.24 (3), p.429-442

2006

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Design, Synthesis, Radiolabeling, and in Vivo Evaluation of Carbon-11 Labeled N-[2-[4-(3-Cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a Potential Positron Emission Tomography Tracer for the Dopamine D4 Receptors

Journal of medicinal chemistry, 2010-10, Vol.53 (20), p.7344-7355

2010

Volltextzugriff (PDF)

Liquid chromatographic assay for riluzole in mouse plasma and central nervous system tissues

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-04, Vol.803 (2), p.305-309

2004

Volltextzugriff (PDF)

Enhancement of cortical extracellular 5-HT by 5-HT1A and 5-HT2C receptor blockade restores the antidepressant-like effect of citalopram in non-responder mice

The international journal of neuropsychopharmacology, 2009-07, Vol.12 (6), p.793-803

2009

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Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies

Journal of medicinal chemistry, 1999-10, Vol.42 (21), p.4362-4379

1999

Volltextzugriff (PDF)

SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by α-synuclein or amyloid-β (1-42) peptide

Journal of neurochemistry, 2009-09, Vol.110 (5), p.1445-1456

2009

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Metabolism of the newer antidepressants : An overview of the pharmacological and pharmacokinetic implications

Clinical pharmacokinetics, 1998-04, Vol.34 (4), p.281-302

CACCIA, S

1998

Volltextzugriff (PDF)

Optimized Synthesis of AMPA Receptor Antagonist ZK 187638 and Neurobehavioral Activity in a Mouse Model of Neuronal Ceroid Lipofuscinosis

ChemMedChem, 2006-10, Vol.1 (10), p.1142-1148

2006

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Antipsychotic drug toxicology in children

Expert opinion on drug metabolism & toxicology, 2011-05, Vol.7 (5), p.591-608

2011

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Safety and Pharmacokinetics of Atypical Antipsychotics in Children and Adolescents

N-dealkylation of arylpiperazine derivatives: disposition and metabolism of the 1-aryl-piperazines formed

Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat

LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

A new generation of antipsychotics: pharmacology and clinical utility of cariprazine in schizophrenia

Genotype-Dependent Activity of Tryptophan Hydroxylase-2 Determines the Response to Citalopram in a Mouse Model of Depression

Liquid chromatography–tandem mass spectrometry of I3,II8-biapigenin, the major biflavone in Hypericum perforatum extracts

St. John's wort components and the brain: uptake, concentrations reached and the mechanisms underlying pharmacological effects

Limbic Seizures Induce P-Glycoprotein in Rodent Brain: Functional Implications for Pharmacoresistance

Optimization of 4‑Aminoquinoline/Clotrimazole-Based Hybrid Antimalarials: Further Structure–Activity Relationships, in Vivo Studies, and Preliminary Toxicity Profiling

Pyrroloquinoxaline hydrazones as fluorescent probes for amyloid fibrils

Pharmacokinetics and metabolism update for some recent antipsychotics

New atypical antipsychotics for schizophrenia: iloperidone

A mouse model of familial ALS has increased CNS levels of endogenous ubiquinol9/10 and does not benefit from exogenous administration of ubiquinol10

Antidepressant-like components of Hypericum perforatum extracts: an overview of their pharmacokinetics and metabolism

A Pilot Study on Brain‐to‐Plasma Partition of 10,11‐Dyhydro‐10‐hydroxy‐5H‐dibenzo(b,f)azepine‐5‐carboxamide and MDR1 Brain Expression in Epilepsy Patients Not Responding to Oxcarbazepine

Determinants of drug brain uptake in a rat model of seizure-associated malformations of cortical development

Design, Synthesis, Radiolabeling, and in Vivo Evaluation of Carbon-11 Labeled N-[2-[4-(3-Cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a Potential Positron Emission Tomography Tracer for the Dopamine D4 Receptors

Liquid chromatographic assay for riluzole in mouse plasma and central nervous system tissues

Enhancement of cortical extracellular 5-HT by 5-HT1A and 5-HT2C receptor blockade restores the antidepressant-like effect of citalopram in non-responder mice

Pyrroloquinoxaline Derivatives as High-Affinity and Selective 5-HT3 Receptor Agonists: Synthesis, Further Structure−Activity Relationships, and Biological Studies

SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by α-synuclein or amyloid-β (1-42) peptide

Metabolism of the newer antidepressants : An overview of the pharmacological and pharmacokinetic implications

Optimized Synthesis of AMPA Receptor Antagonist ZK 187638 and Neurobehavioral Activity in a Mouse Model of Neuronal Ceroid Lipofuscinosis

Antipsychotic drug toxicology in children

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