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Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma

Cancer research (Chicago, Ill.), 2016-12, Vol.76 (23), p.6964-6974

2016

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The complementarity of DDR, nucleic acids and anti-tumour immunity

Nature (London), 2023-07, Vol.619 (7970), p.475-486

2023

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CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

The Journal of clinical investigation, 2011-06, Vol.121 (6), p.2371-2382

2011

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Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells

Cancer discovery, 2017-01, Vol.7 (1), p.72-85

2017

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Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

Nature communications, 2017-06, Vol.8 (1), p.15908-12, Article 15908

2017

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Immunotherapy: A useful strategy to help combat multidrug resistance

Drug resistance updates, 2012-02, Vol.15 (1), p.106-113

Curiel, Tyler J

2012

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Host miR155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanism

Cancer research (Chicago, Ill.), 2015-02, Vol.75 (3), p.519-531

2015

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Adipose PD-L1 Modulates PD-1/PD-L1 Checkpoint Blockade Immunotherapy Efficacy in Breast Cancer

Oncoimmunology, 2018-11, Vol.7 (11), p.e1500107-e1500107

2018

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Tregs and rethinking cancer immunotherapy

The Journal of clinical investigation, 2007-05, Vol.117 (5), p.1167-1174

Curiel, Tyler J

2007

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CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade

Cancer research (Chicago, Ill.), 2020-11, Vol.80 (22), p.5063-5075

2020

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Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents

International journal of molecular sciences, 2022-05, Vol.23 (9), p.5129

2022

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Graft-versus-host disease is enhanced by selective CD73 blockade in mice

PloS one, 2013-03, Vol.8 (3), p.e58397-e58397

2013

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Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model

Experimental gerontology, 2018-05, Vol.105, p.146-154

2018

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Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

Nature medicine, 2001-12, Vol.7 (12), p.1339-1346

2001

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Mitigating Age-Related Immune Dysfunction Heightens the Efficacy of Tumor Immunotherapy in Aged Mice

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8), p.2089-2099

2012

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B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses

The Journal of immunology (1950), 2010-09, Vol.185 (5), p.2747-2753

2010

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Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy

Cancer medicine (Malden, MA), 2021-03, Vol.10 (6), p.2137-2152

2021

Volltextzugriff (PDF)

Optimization of immunotherapy in elderly cancer patients

Critical reviews in oncogenesis, 2013, Vol.18 (6), p.573

2013

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Regulatory T cells and treatment of cancer

Current opinion in immunology, 2008-04, Vol.20 (2), p.241-246

Curiel, Tyler J

2008

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Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

Oncoimmunology, 2019-08, Vol.8 (8), p.1614857

2019

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Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch

Journal for immunotherapy of cancer, 2021-01, Vol.9 (1), p.e001932

2021

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Sequential intravesical mitomycin plus Bacillus Calmette-Guérin for non-muscle-invasive urothelial bladder carcinoma: translational and phase I clinical trial

Clinical cancer research, 2015-01, Vol.21 (2), p.303-311

2015

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Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer

Signal transduction and targeted therapy, 2016-01, Vol.1 (1), p.16030, Article 16030

2016

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Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer

Cancer research (Chicago, Ill.), 2004-08, Vol.64 (16), p.5535-5538

2004

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Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma

The complementarity of DDR, nucleic acids and anti-tumour immunity

CD73 has distinct roles in nonhematopoietic and hematopoietic cells to promote tumor growth in mice

Interventions to Slow Aging in Humans: Are We Ready?

Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis

Immunotherapy: A useful strategy to help combat multidrug resistance

Host miR155 promotes tumor growth through a myeloid-derived suppressor cell-dependent mechanism

Adipose PD-L1 Modulates PD-1/PD-L1 Checkpoint Blockade Immunotherapy Efficacy in Breast Cancer

Tregs and rethinking cancer immunotherapy

CD122-Selective IL2 Complexes Reduce Immunosuppression, Promote Treg Fragility, and Sensitize Tumor Response to PD-L1 Blockade

Pharmacologic Tumor PDL1 Depletion with Cefepime or Ceftazidime Promotes DNA Damage and Sensitivity to DNA-Damaging Agents

Graft-versus-host disease is enhanced by selective CD73 blockade in mice

Age effects of distinct immune checkpoint blockade treatments in a mouse melanoma model

Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells

Mitigating Age-Related Immune Dysfunction Heightens the Efficacy of Tumor Immunotherapy in Aged Mice

B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses

Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy

Optimization of immunotherapy in elderly cancer patients

Regulatory T cells and treatment of cancer

Percutaneous BCG enhances innate effector antitumor cytotoxicity during treatment of bladder cancer: a translational clinical trial

Estrogen receptor beta signaling in CD8+ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch

Sequential intravesical mitomycin plus Bacillus Calmette-Guérin for non-muscle-invasive urothelial bladder carcinoma: translational and phase I clinical trial

Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer

Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer

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