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The eukaryotic translation initiation factor eIF4E reprograms alternative splicing

The EMBO journal, 2023-04, Vol.42 (7), p.e110496-n/a

2023

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The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

eLife, 2017-11, Vol.6

2017

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A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

RNA (Cambridge), 2017-06, Vol.23 (6), p.927-937

2017

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The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

Nature (London), 2014-07, Vol.511 (7507), p.90-93

2014

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Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine

Haematologica (Roma), 2023-11, Vol.108 (11), p.2946-2958

2023

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Aiding and abetting cancer: mRNA export and the nuclear pore

Trends in cell biology, 2013-07, Vol.23 (7), p.328-335

2013

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Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

Leukemia & lymphoma, 2010-10, Vol.51 (10), p.1805-1815

2010

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eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.3877-3882

2013

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eIF4E orchestrates mRNA processing, RNA export and translation to modify specific protein production

Nucleus (Austin, Tex.), 2024-12, Vol.15 (1), p.2360196

2024

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The Cap-Binding Complex CBC and the Eukaryotic Translation Factor eIF4E: Co-Conspirators in Cap-Dependent RNA Maturation and Translation

Cancers, 2021-12, Vol.13 (24), p.6185

2021

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The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

Cell reports (Cambridge), 2012-08, Vol.2 (2), p.207-215

2012

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A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

Haematologica (Roma), 2015-01, Vol.100 (1), p.e7-e9

2015

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The Impact of Post-transcriptional Control: Better Living Through RNA Regulons

Frontiers in genetics, 2018-11, Vol.9, p.512-512

2018

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Importin 8 mediates m⁷G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (19), p.5263-5268

2016

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The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia

Leukemia, 2013-10, Vol.27 (10), p.2047-2055

2013

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Subcellular Fractionation Suitable for Studies of RNA and Protein Trafficking

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2502, p.91

2022

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Identification and Characterization of the Interaction Between the Methyl-7-Guanosine Cap Maturation Enzyme RNMT and the Cap-Binding Protein eIF4E

Journal of molecular biology, 2022-03, Vol.434 (5), p.167451-167451, Article 167451

2022

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Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (48), p.24056-24065

2019

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Medicinal Chemistry and NMR Driven Discovery of Novel UDP-glucuronosyltransferase 1A Inhibitors That Overcome Therapeutic Resistance in Cells

Journal of molecular biology, 2024-01, Vol.436 (2), p.168378-168378, Article 168378

2024

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XPO1 Enables Adaptive Regulation of mRNA Export Required for Genotoxic Stress Tolerance in Cancer Cells

Cancer research (Chicago, Ill.), 2024-01, Vol.84 (1), p.101-117

2024

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GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs

ACS chemical biology, 2019-03, Vol.14 (3), p.348-355

2019

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The eukaryotic translation initiation factor eIF4E elevates steady-state m⁷G capping of coding and noncoding transcripts

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (43), p.26773-26783

2020

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The eukaryotic translation initiation factor eIF4E elevates steady-state m 7 G capping of coding and noncoding transcripts

Proceedings of the National Academy of Sciences - PNAS, 2020-10, Vol.117 (43), p.26773-26783

2020

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Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia

Oncogene, 2019-03, Vol.38 (13), p.2241-2262

2019

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The eukaryotic translation initiation factor eIF4E reprograms alternative splicing

The eukaryotic translation initiation factor eIF4E harnesses hyaluronan production to drive its malignant activity

A biochemical framework for eIF4E-dependent mRNA export and nuclear recycling of the export machinery

The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation

Molecular targeting of the UDP-glucuronosyltransferase enzymes in high-eukaryotic translation initiation factor 4E refractory/relapsed acute myeloid leukemia patients: a randomized phase II trial of vismodegib, ribavirin with or without decitabine

Aiding and abetting cancer: mRNA export and the nuclear pore

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

eIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognition

eIF4E orchestrates mRNA processing, RNA export and translation to modify specific protein production

The Cap-Binding Complex CBC and the Eukaryotic Translation Factor eIF4E: Co-Conspirators in Cap-Dependent RNA Maturation and Translation

The Oncogene eIF4E Reprograms the Nuclear Pore Complex to Promote mRNA Export and Oncogenic Transformation

A phase I trial of ribavirin and low-dose cytarabine for the treatment of relapsed and refractory acute myeloid leukemia with elevated eIF4E

The Impact of Post-transcriptional Control: Better Living Through RNA Regulons

Importin 8 mediates m⁷G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E

The eukaryotic translation initiation factor eIF4E is a direct transcriptional target of NF-κB and is aberrantly regulated in acute myeloid leukemia

Subcellular Fractionation Suitable for Studies of RNA and Protein Trafficking

Identification and Characterization of the Interaction Between the Methyl-7-Guanosine Cap Maturation Enzyme RNMT and the Cap-Binding Protein eIF4E

Structural studies of the eIF4E–VPg complex reveal a direct competition for capped RNA: Implications for translation

Medicinal Chemistry and NMR Driven Discovery of Novel UDP-glucuronosyltransferase 1A Inhibitors That Overcome Therapeutic Resistance in Cells

Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphomas

XPO1 Enables Adaptive Regulation of mRNA Export Required for Genotoxic Stress Tolerance in Cancer Cells

GLI1-Inducible Glucuronidation Targets a Broad Spectrum of Drugs

The eukaryotic translation initiation factor eIF4E elevates steady-state m⁷G capping of coding and noncoding transcripts

The eukaryotic translation initiation factor eIF4E elevates steady-state m 7 G capping of coding and noncoding transcripts

Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia

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