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Real-World Evidence, Causal Inference, and Machine Learning

Value in health, 2019-05, Vol.22 (5), p.587-592

Crown, William H.

2019

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Potential Application of Machine Learning in Health Outcomes Research and Some Statistical Cautions

Value in health, 2015-03, Vol.18 (2), p.137-140

Crown, William H., PhD

2015

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Comparative Effectiveness of Different Treatment Pathways for Opioid Use Disorder

JAMA network open, 2020-02, Vol.3 (2), p.e1920622

2020

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Deep neural network models for identifying incident dementia using claims and EHR datasets

PloS one, 2020-09, Vol.15 (9), p.e0236400-e0236400

2020

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Optum Labs: building a novel node in the learning health care system

Health Affairs, 2014-07, Vol.33 (7), p.1187-1194

2014

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Propensity-Score Matching in Economic Analyses: Comparison with Regression Models, Instrumental Variables, Residual Inclusion, Differences-in-Differences, and Decomposition Methods

Applied health economics and health policy, 2014-02, Vol.12 (1), p.7-18

Crown, William H.

2014

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Decomposition analysis as a framework for understanding heterogeneity of treatment effects in non‐randomized health care studies

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2021-09, Vol.20 (5), p.945-951

Crown, William H.

2021

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How Can We Make More Rapid Progress in the Leveraging of Real-World Evidence by Regulatory Decision Makers?

Value in health, 2022-02, Vol.25 (2), p.167-170

2022

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The Potential Role of Constrained Optimization Methods in Healthcare Decision Making

Applied health economics and health policy, 2020-08, Vol.18 (4), p.461-462

Crown, William H.

2020

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Can Observational Analyses of Routinely Collected Data Emulate Randomized Trials? Design and Feasibility of the Observational Patient Evidence for Regulatory Approval Science and Understanding Disease Project

Value in health, 2023-02, Vol.26 (2), p.176-184

2023

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Effect of Adherence to Oral Anticoagulants on Risk of Stroke and Major Bleeding Among Patients With Atrial Fibrillation

Journal of the American Heart Association, 2016-02, Vol.5 (2), p.n/a

2016

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Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis

Value in health, 2021-01, Vol.24 (1), p.116-117

2021

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Issues in the registration of database studies

Journal of clinical epidemiology, 2020-05, Vol.121, p.29-31

2020

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Analysis of economic and educational spillover effects in PEPFAR countries

PloS one, 2023-12, Vol.18 (12), p.e0289909-e0289909

2023

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Applying Dynamic Simulation Modeling Methods in Health Care Delivery Research—The SIMULATE Checklist: Report of the ISPOR Simulation Modeling Emerging Good Practices Task Force

Value in health, 2015, Vol.18 (1), p.5-16

2015

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Specification Issues in a Big Data Context: Controlling for the Endogeneity of Consumer and Provider Behaviours in Healthcare Treatment Effects Models

PharmacoEconomics, 2016-02, Vol.34 (2), p.95-100

Crown, William H.

2016

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Underutilization of BRCA1/2 testing to guide breast cancer treatment: black and Hispanic women particularly at risk

Genetics in medicine, 2011-04, Vol.13 (4), p.349-355

2011

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ATRAcTR (Authentic Transparent Relevant Accurate Track-Record): a screening tool to assess the potential for real-world data sources to support creation of credible real-world evidence for regulatory decision-making

Health services and outcomes research methodology, 2024-09, Vol.24 (3), p.348-365

2024

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Constrained Optimization Methods in Health Services Research—An Introduction: Report 1 of the ISPOR Optimization Methods Emerging Good Practices Task Force

Value in health, 2017-03, Vol.20 (3), p.310-319

2017

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Analysis of maternal and child health spillover effects in PEPFAR countries

BMJ open, 2023-12, Vol.13 (12), p.e070221-e070221

2023

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Improving transparency to build trust in real‐world secondary data studies for hypothesis testing—Why, what, and how: recommendations and a road map from the real‐world evidence transparency initiative

Pharmacoepidemiology and drug safety, 2020-11, Vol.29 (11), p.1504-1513

2020

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Relative Cost Differences of Initial Treatment Strategies for Newly Diagnosed Opioid Use Disorder: A Cohort Study

Medical care, 2020-10, Vol.58 (10), p.919-926

2020

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Selecting a Dynamic Simulation Modeling Method for Health Care Delivery Research—Part 2: Report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force

Value in health, 2015-03, Vol.18 (2), p.147-160

2015

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A Questionnaire to Assess the Relevance and Credibility of Observational Studies to Inform Health Care Decision Making: An ISPOR-AMCP-NPC Good Practice Task Force Report

Value in health, 2014-03, Vol.17 (2), p.143-156

2014

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Good Research Practices for Comparative Effectiveness Research: Analytic Methods to Improve Causal Inference from Nonrandomized Studies of Treatment Effects Using Secondary Data Sources: The ISPOR Good Research Practices for Retrospective Database Analysis Task Force Report—Part III

Value in health, 2009-11, Vol.12 (8), p.1062-1073

2009

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Real-World Evidence, Causal Inference, and Machine Learning

Potential Application of Machine Learning in Health Outcomes Research and Some Statistical Cautions

Comparative Effectiveness of Different Treatment Pathways for Opioid Use Disorder

Deep neural network models for identifying incident dementia using claims and EHR datasets

Optum Labs: building a novel node in the learning health care system

Propensity-Score Matching in Economic Analyses: Comparison with Regression Models, Instrumental Variables, Residual Inclusion, Differences-in-Differences, and Decomposition Methods

Decomposition analysis as a framework for understanding heterogeneity of treatment effects in non‐randomized health care studies

How Can We Make More Rapid Progress in the Leveraging of Real-World Evidence by Regulatory Decision Makers?

The Potential Role of Constrained Optimization Methods in Healthcare Decision Making

Can Observational Analyses of Routinely Collected Data Emulate Randomized Trials? Design and Feasibility of the Observational Patient Evidence for Regulatory Approval Science and Understanding Disease Project

Effect of Adherence to Oral Anticoagulants on Risk of Stroke and Major Bleeding Among Patients With Atrial Fibrillation

Real-World Evidence: Understanding Sources of Variability Through Empirical Analysis

Issues in the registration of database studies

Analysis of economic and educational spillover effects in PEPFAR countries

Applying Dynamic Simulation Modeling Methods in Health Care Delivery Research—The SIMULATE Checklist: Report of the ISPOR Simulation Modeling Emerging Good Practices Task Force

Specification Issues in a Big Data Context: Controlling for the Endogeneity of Consumer and Provider Behaviours in Healthcare Treatment Effects Models

Underutilization of BRCA1/2 testing to guide breast cancer treatment: black and Hispanic women particularly at risk

ATRAcTR (Authentic Transparent Relevant Accurate Track-Record): a screening tool to assess the potential for real-world data sources to support creation of credible real-world evidence for regulatory decision-making

Constrained Optimization Methods in Health Services Research—An Introduction: Report 1 of the ISPOR Optimization Methods Emerging Good Practices Task Force

Analysis of maternal and child health spillover effects in PEPFAR countries

Improving transparency to build trust in real‐world secondary data studies for hypothesis testing—Why, what, and how: recommendations and a road map from the real‐world evidence transparency initiative

Relative Cost Differences of Initial Treatment Strategies for Newly Diagnosed Opioid Use Disorder: A Cohort Study

Selecting a Dynamic Simulation Modeling Method for Health Care Delivery Research—Part 2: Report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force

A Questionnaire to Assess the Relevance and Credibility of Observational Studies to Inform Health Care Decision Making: An ISPOR-AMCP-NPC Good Practice Task Force Report

Good Research Practices for Comparative Effectiveness Research: Analytic Methods to Improve Causal Inference from Nonrandomized Studies of Treatment Effects Using Secondary Data Sources: The ISPOR Good Research Practices for Retrospective Database Analysis Task Force Report—Part III

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