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Siglec-mediated regulation of immune cell function in disease

Nature reviews. Immunology, 2014-10, Vol.14 (10), p.653

2014

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Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis

Immunity (Cambridge, Mass.), 2015-07, Vol.43 (1), p.187-199

2015

Volltextzugriff (PDF)

CD169 mediates the capture of exosomes in spleen and lymph node

Blood, 2014-01, Vol.123 (2), p.208-216

2014

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The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

Nature immunology, 2016-11, Vol.17 (11), p.1273

2016

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Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169

PloS one, 2012-06, Vol.7 (6), p.e39039

2012

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Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo

PLoS pathogens, 2014-01, Vol.10 (1), p.e1003846-e1003846

2014

Volltextzugriff (PDF)

Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation

Immunology, 2011-01, Vol.132 (1), p.18-26

2011

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Siglecs as positive and negative regulators of the immune system

Biochemical Society transactions, 2008-12, Vol.36 (Pt 6), p.1467

2008

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Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression

Glycobiology (Oxford), 2020-05, Vol.31 (1), p.44-54

2020

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Sialoadhesin in recognition of self and non-self

Seminars in immunopathology, 2012-05, Vol.34 (3), p.353-364

2012

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Identification of lectin counter-receptors on cell membranes by proximity labeling

Glycobiology (Oxford), 2017-09, Vol.27 (9), p.800-805

2017

Volltextzugriff (PDF)

CD33-related siglecs as potential modulators of inflammatory responses

Annals of the New York Academy of Sciences, 2012-04, Vol.1253 (1), p.102-111

2012

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Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (12), p.3329-3334

2016

Volltextzugriff (PDF)

Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

Proceedings of the National Academy of Sciences - PNAS, 2013-05, Vol.110 (19), p.7826-7831

2013

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Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming

Cell reports (Cambridge), 2018-02, Vol.22 (6), p.1484-1495

2018

Volltextzugriff (PDF)

Siglec and anti-Siglec therapies

Current opinion in chemical biology, 2021-06, Vol.62, p.34-42

2021

Volltextzugriff (PDF)

Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (16), p.5998-6003

2014

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O-glycans direct selectin ligands to lipid rafts on leukocytes

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (28), p.8661-8666

2015

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Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

Journal of biomedical science, 2021-01, Vol.28 (1), p.5-5, Article 5

2021

Volltextzugriff (PDF)

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

eLife, 2016-08, Vol.5

2016

Volltextzugriff (PDF)

Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia

Nature microbiology, 2018-05, Vol.3 (5), p.600

2018

Volltextzugriff (PDF)

Lectin Receptors Expressed on Myeloid Cells

Microbiology spectrum, 2016-10, Vol.4 (5)

2016

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Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner

The Journal of biological chemistry, 2015-11, Vol.290 (45), p.27345-27359

2015

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Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis

Frontiers in immunology, 2021-10, Vol.12, p.744184

2021

Volltextzugriff (PDF)

Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

Journal of molecular medicine (Berlin, Germany), 2014-09, Vol.92 (9), p.951-959

2014

Volltextzugriff (PDF)

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Siglec-mediated regulation of immune cell function in disease

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis

CD169 mediates the capture of exosomes in spleen and lymph node

The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9

Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169

Group B Streptococcus engages an inhibitory Siglec through sialic acid mimicry to blunt innate immune and inflammatory responses in vivo

Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation

Siglecs as positive and negative regulators of the immune system

Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression

Sialoadhesin in recognition of self and non-self

Identification of lectin counter-receptors on cell membranes by proximity labeling

CD33-related siglecs as potential modulators of inflammatory responses

Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells

Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation

Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming

Siglec and anti-Siglec therapies

Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies

O-glycans direct selectin ligands to lipid rafts on leukocytes

Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

Intracellular replication of Streptococcus pneumoniae inside splenic macrophages serves as a reservoir for septicaemia

Lectin Receptors Expressed on Myeloid Cells

Mouse Siglec-1 Mediates trans-Infection of Surface-bound Murine Leukemia Virus in a Sialic Acid N-Acyl Side Chain-dependent Manner

Siglec-7 Mediates Immunomodulation by Colorectal Cancer-Associated Fusobacterium nucleatum ssp. animalis

Role of macrophage sialoadhesin in host defense against the sialylated pathogen group B Streptococcus

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