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Characteristics of Photoreceptor PDE (PDE6): similarities and differences to PDE5

International journal of impotence research, 2004-06, Vol.16 (S1), p.S28-S33

Cote, R H

2004

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Intracellular cGMP concentration in rod photoreceptors is regulated by binding to high and moderate affinity cGMP binding sites

The Journal of biological chemistry, 1993-08, Vol.268 (23), p.17190-17198

1993

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The Catalytic and GAF Domains of the Rod cGMP Phosphodiesterase (PDE6) Heterodimer Are Regulated by Distinct Regions of Its Inhibitory γ Subunit

The Journal of biological chemistry, 2001-07, Vol.276 (29), p.27527-27534

2001

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cGMP Binding Sites on Photoreceptor Phosphodiesterase: Role in Feedback Regulation of Visual Transduction

Proceedings of the National Academy of Sciences - PNAS, 1994-05, Vol.91 (11), p.4845-4849

1994

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Molecular organization of bovine rod cGMP-phosphodiesterase 6

Journal of molecular biology, 2001-07, Vol.310 (4), p.781-791

2001

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Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors

The Journal of biological chemistry, 1984-08, Vol.259 (15), p.9635-9641

1984

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Mechanism of Transducin Activation of Frog Rod Photoreceptor Phosphodiesterase ALLOSTERIC INTERACTIONS BETWEEN THE INHIBITORY gamma SUBUNIT AND THE NONCATALYTIC cGMP-BINDING SITES

The Journal of biological chemistry, 2000-12, Vol.275 (49), p.38611-38619

2000

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Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites

Biochemical journal, 1999-06, Vol.340 ( Pt 3) (3), p.863-869

1999

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[43] Kinetics and regulation of cGMP binding to noncatalytic binding sites on photoreceptor phosphodiesterase

Methods in Enzymology, 2000, Vol.315, p.646-672

Cote, Rick x.

2000

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cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits

The Journal of biological chemistry, 1999-06, Vol.274 (26), p.18813-18820

1999

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Changes in cGMP concentration correlate with some, but not all, aspects of the light-regulated conductance of frog rod photoreceptors

The Journal of biological chemistry, 1986-10, Vol.261 (28), p.12965-12975

1986

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Cyclic GMP levels and membrane current during onset, recovery, and light adaptation of the photoresponse of detached frog photoreceptors

The Journal of biological chemistry, 1989-09, Vol.264 (26), p.15384-15391

1989

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A Centrifugal Separation Procedure Detects Moderate Affinity cGMP Binding Sites in Membrane-Associated Proteins and Permeabilized Cells

Analytical biochemistry, 1993-11, Vol.215 (1), p.159-161

1993

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Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors

The Journal of general physiology, 1994, Vol.103 (1), p.67-86

1994

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cGMP influences guanine nucleotide binding to frog photoreceptor G-protein

The Journal of biological chemistry, 1986-01, Vol.261 (1), p.313-318

1986

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cGMP signaling in vertebrate retinal photoreceptor cells

Frontiers in bioscience, 2005-05, Vol.10, p.1191

2005

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Potency and Mechanism of Action of E4021, a Type 5 Phosphodiesterase Isozyme-Selective Inhibitor, on the Photoreceptor Phosphodiesterase Depend on the State of Activation of the Enzyme

Molecular pharmacology, 1999-03, Vol.55 (3), p.508-514

1999

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Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phosphodiesterase Using cGMP Analogs

The Journal of biological chemistry, 1998-03, Vol.273 (10), p.5557-5565

1998

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Efficacy and Selectivity of Phosphodiesterase-Targeted Drugs in Inhibiting Photoreceptor Phosphodiesterase (PDE6) in Retinal Photoreceptors

Investigative ophthalmology & visual science, 2005-09, Vol.46 (9), p.3060-3066

2005

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Photoreceptor Phosphodiesterase: Interaction of Inhibitory γ Subunit and Cyclic GMP with Specific Binding Sites on Catalytic Subunits

Methods (San Diego, Calif.), 1998-01, Vol.14 (1), p.93-104

1998

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Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5: PDE-5 Inhibitor Therapy for Erectile Dysfunction

International journal of impotence research, 2004, Vol.16, p.S28-S33

COTE, R. H

2004

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The Glutamic Acid-rich Protein-2 (GARP2) Is a High Affinity Rod Photoreceptor Phosphodiesterase (PDE6)-binding Protein That Modulates Its Catalytic Properties

The Journal of biological chemistry, 2006-03, Vol.281 (9), p.5500-5505

2006

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Evaluation of the 17-kDa Prenyl-binding Protein as a Regulatory Protein for Phototransduction in Retinal Photoreceptors

The Journal of biological chemistry, 2005-01, Vol.280 (2), p.1248-1256

2005

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Release of Escherichia coli DNA from Membrane Complexes by Single-Strand Endonucleases

Proceedings of the National Academy of Sciences - PNAS, 1977-07, Vol.74 (7), p.2756-2760

1977

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Rod and cone opsin families differ in spectral tuning domains but not signal transducing domains as judged by saturated evolutionary trace analysis

Journal of molecular evolution, 2005-07, Vol.61 (1), p.75-89

2005

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Characteristics of Photoreceptor PDE (PDE6): similarities and differences to PDE5

Intracellular cGMP concentration in rod photoreceptors is regulated by binding to high and moderate affinity cGMP binding sites

The Catalytic and GAF Domains of the Rod cGMP Phosphodiesterase (PDE6) Heterodimer Are Regulated by Distinct Regions of Its Inhibitory γ Subunit

cGMP Binding Sites on Photoreceptor Phosphodiesterase: Role in Feedback Regulation of Visual Transduction

Molecular organization of bovine rod cGMP-phosphodiesterase 6

Light-induced decreases in cGMP concentration precede changes in membrane permeability in frog rod photoreceptors

Mechanism of Transducin Activation of Frog Rod Photoreceptor Phosphodiesterase ALLOSTERIC INTERACTIONS BETWEEN THE INHIBITORY gamma SUBUNIT AND THE NONCATALYTIC cGMP-BINDING SITES

Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites

[43] Kinetics and regulation of cGMP binding to noncatalytic binding sites on photoreceptor phosphodiesterase

cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits

Changes in cGMP concentration correlate with some, but not all, aspects of the light-regulated conductance of frog rod photoreceptors

Cyclic GMP levels and membrane current during onset, recovery, and light adaptation of the photoresponse of detached frog photoreceptors

A Centrifugal Separation Procedure Detects Moderate Affinity cGMP Binding Sites in Membrane-Associated Proteins and Permeabilized Cells

Regulation of intracellular cyclic GMP concentration by light and calcium in electropermeabilized rod photoreceptors

cGMP influences guanine nucleotide binding to frog photoreceptor G-protein

cGMP signaling in vertebrate retinal photoreceptor cells

Potency and Mechanism of Action of E4021, a Type 5 Phosphodiesterase Isozyme-Selective Inhibitor, on the Photoreceptor Phosphodiesterase Depend on the State of Activation of the Enzyme

Structural Features of the Noncatalytic cGMP Binding Sites of Frog Photoreceptor Phosphodiesterase Using cGMP Analogs

Efficacy and Selectivity of Phosphodiesterase-Targeted Drugs in Inhibiting Photoreceptor Phosphodiesterase (PDE6) in Retinal Photoreceptors

Photoreceptor Phosphodiesterase: Interaction of Inhibitory γ Subunit and Cyclic GMP with Specific Binding Sites on Catalytic Subunits

Characteristics of photoreceptor PDE (PDE6): similarities and differences to PDE5: PDE-5 Inhibitor Therapy for Erectile Dysfunction

The Glutamic Acid-rich Protein-2 (GARP2) Is a High Affinity Rod Photoreceptor Phosphodiesterase (PDE6)-binding Protein That Modulates Its Catalytic Properties

Evaluation of the 17-kDa Prenyl-binding Protein as a Regulatory Protein for Phototransduction in Retinal Photoreceptors

Release of Escherichia coli DNA from Membrane Complexes by Single-Strand Endonucleases

Rod and cone opsin families differ in spectral tuning domains but not signal transducing domains as judged by saturated evolutionary trace analysis

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