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Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation

CPT: pharmacometrics and systems pharmacology, 2016-03, Vol.5 (3), p.93-122

2016

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Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole

American journal of physiology. Heart and circulatory physiology, 2018-11, Vol.315 (5), p.H1137-H1147

2018

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IPD3 Controls the Formation of Nitrogen-Fixing Symbiosomes in Pea and Medicago Spp

Molecular plant-microbe interactions, 2011-11, Vol.24 (11), p.1333-1344

2011

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Population pharmacokinetics of nelfinavir (NFV) and its metabolite M8 when administered with ritonavir (RTV)

Clinical pharmacology and therapeutics, 2004-02, Vol.75 (2), p.P84-P84

2004

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Efficient transposition of the Tnt1 tobacco retrotransposon in the model legume Medicago truncatula

The Plant journal : for cell and molecular biology, 2003-04, Vol.34 (1), p.95-106

2003

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Mixed effect modeling of sumatriptan pharmacokinetics during drug development : II. From healthy subjects to phase 2 dose ranging in patients

Journal of pharmacokinetics and biopharmaceutics, 1999-04, Vol.27 (2), p.149-171

1999

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Rapid inactivation of the maize transposable element En/Spm in Medicago truncatula

Molecular genetics and genomics : MGG, 2003-09, Vol.269 (6), p.732-745

2003

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P4757Inhibitory g protein and phosphodiesterases 3,4 regulate compartmentation of beta-1 and beta-2 adrenoceptor-evoked inotropic responses elicited through activation of either adenylyl cyclase 5 or 6

European heart journal, 2018-08, Vol.39 (suppl_1)

2018

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Mixed effect modeling of sumatriptan pharmacokinetics during drug development. I: Interspecies allometric scaling

Journal of pharmacokinetics and biopharmaceutics, 1997-04, Vol.25 (2), p.149-167

1997

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P1744Hypothermia-induced diastolic dysfunction in ventricular trabeculae from human failing explanted hearts is caused by elongated contraction-relaxation cycle time and is worsened by increased heart rate

European heart journal, 2018-08, Vol.39 (suppl_1)

2018

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Population pharmacokinetics of docetaxel during phase I studies using nonlinear mixed-effect modeling and nonparametric maximum-likelihood estimation

Cancer chemotherapy and pharmacology, 1995-01, Vol.37 (1-2), p.47-54

1995

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From pollen tubes to infection threads: recruitment of Medicago floral pectic genes for symbiosis

The Plant journal : for cell and molecular biology, 2004-08, Vol.39 (4), p.587-598

2004

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Population pharmacokinetics of bevacizumab

Journal of clinical oncology, 2008-05, Vol.26 (15_suppl), p.14570-14570

2008

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T-DNA tagging in the model legume Medicago truncatula allows efficient gene discovery

Molecular breeding, 2002-01, Vol.10 (4), p.203-215

2002

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low level of activity of Arabidopsis thaliana Tag1 transposon correlates with the absence of two minor transcripts in Medicago truncatula

Molecular breeding, 2006-05, Vol.17 (4), p.317-328

2006

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Efficient transposition of the Tnt1 tobacco retrotransposon in the model legume Medicago truncatula

The Plant journal : for cell and molecular biology, 2003, Vol.34 (1), p.95-106

2003

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Pharmacokinetics of total and free digoxin and Fab fragments in 5 intoxicated patients after administration of specific anti-digoxin Fab fragments

Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1991, Vol.14, p.132

1991

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Evaluation of Bayesian estimation in comparison to NONMEM for population pharmacokinetic data analysis : application to pefloxacin in intensive care unit patients

Journal of pharmacokinetics and biopharmaceutics, 1992-12, Vol.20 (6), p.653-669

1992

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Pharmacokinetics of total and free digoxin and Fab fragments in 5 intoxicated patients after administration of specific anti-digoxin Fab fragments

Archives of Toxicology [ARCH. TOXICOL.]. 1991, 1991

1991

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Spatial genetic structure of a small rodent in a heterogeneous landscape

Molecular ecology, 2008-11, Vol.17 (21), p.4619-4629

2008

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Sperm motility of externally fertilizing fish and amphibians

Theriogenology, 2015-01, Vol.83 (1), p.1-13.e8

2015

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Renal transplantation in 4 patients with methylmalonic aciduria: A cell therapy for metabolic disease

Molecular genetics and metabolism, 2013-09, Vol.110 (1-2), p.106-110

2013

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Parameterisation of the NCSOIL model to simulate C and N short-term mineralisation of exogenous organic matter in different soils

Soil biology & biochemistry, 2017-01, Vol.104, p.128-140

2017

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Mediterranean populations of the lesser white-toothed shrew (Crocidura suaveolens group): an unexpected puzzle of Pleistocene survivors and prehistoric introductions

Molecular ecology, 2007-08, Vol.16 (16), p.3438-3452

2007

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Long-term outcome in methylmalonic aciduria: A series of 30 French patients

Molecular genetics and metabolism, 2009-07, Vol.97 (3), p.172-178

2009

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Good Practices in Model‐Informed Drug Discovery and Development: Practice, Application, and Documentation

Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole

IPD3 Controls the Formation of Nitrogen-Fixing Symbiosomes in Pea and Medicago Spp

Population pharmacokinetics of nelfinavir (NFV) and its metabolite M8 when administered with ritonavir (RTV)

Efficient transposition of the Tnt1 tobacco retrotransposon in the model legume Medicago truncatula

Mixed effect modeling of sumatriptan pharmacokinetics during drug development : II. From healthy subjects to phase 2 dose ranging in patients

Rapid inactivation of the maize transposable element En/Spm in Medicago truncatula

P4757Inhibitory g protein and phosphodiesterases 3,4 regulate compartmentation of beta-1 and beta-2 adrenoceptor-evoked inotropic responses elicited through activation of either adenylyl cyclase 5 or 6

Mixed effect modeling of sumatriptan pharmacokinetics during drug development. I: Interspecies allometric scaling

P1744Hypothermia-induced diastolic dysfunction in ventricular trabeculae from human failing explanted hearts is caused by elongated contraction-relaxation cycle time and is worsened by increased heart rate

Population pharmacokinetics of docetaxel during phase I studies using nonlinear mixed-effect modeling and nonparametric maximum-likelihood estimation

From pollen tubes to infection threads: recruitment of Medicago floral pectic genes for symbiosis

Population pharmacokinetics of bevacizumab

T-DNA tagging in the model legume Medicago truncatula allows efficient gene discovery

low level of activity of Arabidopsis thaliana Tag1 transposon correlates with the absence of two minor transcripts in Medicago truncatula

Efficient transposition of the Tnt1 tobacco retrotransposon in the model legume Medicago truncatula

Pharmacokinetics of total and free digoxin and Fab fragments in 5 intoxicated patients after administration of specific anti-digoxin Fab fragments

Evaluation of Bayesian estimation in comparison to NONMEM for population pharmacokinetic data analysis : application to pefloxacin in intensive care unit patients

Pharmacokinetics of total and free digoxin and Fab fragments in 5 intoxicated patients after administration of specific anti-digoxin Fab fragments

Spatial genetic structure of a small rodent in a heterogeneous landscape

Sperm motility of externally fertilizing fish and amphibians

Renal transplantation in 4 patients with methylmalonic aciduria: A cell therapy for metabolic disease

Parameterisation of the NCSOIL model to simulate C and N short-term mineralisation of exogenous organic matter in different soils

Mediterranean populations of the lesser white-toothed shrew (Crocidura suaveolens group): an unexpected puzzle of Pleistocene survivors and prehistoric introductions

Long-term outcome in methylmalonic aciduria: A series of 30 French patients

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