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Review of recent acetyl-CoA carboxylase inhibitor patents: mid-2007 - 2008

Expert opinion on therapeutic patents, 2009-07, Vol.19 (7), p.943-956

Corbett, Jeffrey W

2009

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Inhibition of Clinically Relevant Mutant Variants of HIV-1 by Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2000-05, Vol.43 (10), p.2019-2030

2000

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Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1

Antimicrobial Agents and Chemotherapy, 1999-12, Vol.43 (12), p.2893-2897

1999

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Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase

Journal of medicinal chemistry, 2012-01, Vol.55 (2), p.935-942

2012

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Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (7), p.2383-2388

2010

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Discovery of triazolopyrimidine-based PDE8B inhibitors: Exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes

Bioorganic & medicinal chemistry letters, 2012-09, Vol.22 (17), p.5721-5726

2012

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Heteroatom-linked indanylpyrazines are corticotropin releasing factor type-1 receptor antagonists

Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6250-6256

2007

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Applications of Vinylogous Mannich Reactions. Asymmetric Synthesis of the Heteroyohimboid Alkaloids (-)-Ajmalicine, (+)-19-epi-Ajmalicine, and (-)-Tetrahydroalstonine

Journal of organic chemistry, 1995-05, Vol.60 (10), p.3236-3242

1995

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Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion

The Journal of biological chemistry, 2011-12, Vol.286 (48), p.41510-41519

2011

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Synthesis of Unprotected Carboxy Indazoles via Pd-Catalyzed Carbonylation

Synthetic communications, 2012-07, Vol.42 (13), p.1914-1921

2012

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Solid-Phase Synthesis of Benzopiperazinones

Journal of organic chemistry, 1998-02, Vol.63 (4), p.1172-1177

1998

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Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase Chemistry

Journal of organic chemistry, 1997-01, Vol.62 (1), p.201-203

1997

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Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 2000-01, Vol.10 (2), p.193-195

2000

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Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase

Bioorganic & medicinal chemistry letters, 2001-02, Vol.11 (3), p.309-312

2001

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3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.211-214

2001

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Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus

MedChemComm, 2011-09, Vol.2 (9), p.828

2011

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Inhibitors of Mammalian Acetyl-CoA Carboxylase

Recent patents on cardiovascular drug discovery, 2007-11, Vol.2 (3), p.162-180

2007

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RECENT PROGRESS IN SOLID PHASE HETEROCYCLE SYNTHESES. A REVIEW

Organic preparations and procedures international, 1998-10, Vol.30 (5), p.489-550

Corbett, Jeffrey W.

1998

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Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzo f uran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus

MedChemComm, 2011-01, Vol.2 (9), p.828-839

2011

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Discovery of second generation quinazolinone non-nucleoside reverse transcriptase inhibitors of HIV-1

Progress in medicinal chemistry, 2002, Vol.40, p.63-105

2002

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3 Discovery of Second Generation Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors of Hiv-1

Progress in Medicinal Chemistry, 2002, Vol.40, p.63-105

2002

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The Stereochemical Course of Nucleophilic Additions of 2-Trialkylsiloxyfurans to Cyclic N-Acyliminium Ions

Synthesis (Stuttgart), 1992, Vol.1992 (1/02), p.55-57

1992

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Solid-phase synthesis of a selective αvβ3 integrin antagonist library

Bioorganic & medicinal chemistry letters, 1997-06, Vol.7 (11), p.1371-1376

1997

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Inhibitors of mammalian acetyl-CoA carboxylase

Recent patents on cardiovascular drug discovery, 2007-11, Vol.2 (3), p.162

2007

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ChemInform Abstract: Trifluoromethyl-Containing 3-Alkoxymethyl- and 3-Aryloxymethyl-2-pyridinones Are Potent Inhibitors of HIV-1 Non-Nucleoside Reverse Transcriptase

ChemInform, 2001-05, Vol.32 (18), p.no-no

2001

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Review of recent acetyl-CoA carboxylase inhibitor patents: mid-2007 - 2008

Inhibition of Clinically Relevant Mutant Variants of HIV-1 by Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors

Expanded-Spectrum Nonnucleoside Reverse Transcriptase Inhibitors Inhibit Clinically Relevant Mutant Variants of Human Immunodeficiency Virus Type 1

Maximizing Lipophilic Efficiency: The Use of Free-Wilson Analysis in the Design of Inhibitors of Acetyl-CoA Carboxylase

Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2

Discovery of triazolopyrimidine-based PDE8B inhibitors: Exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes

Heteroatom-linked indanylpyrazines are corticotropin releasing factor type-1 receptor antagonists

Applications of Vinylogous Mannich Reactions. Asymmetric Synthesis of the Heteroyohimboid Alkaloids (-)-Ajmalicine, (+)-19-epi-Ajmalicine, and (-)-Tetrahydroalstonine

Structure-guided Inhibitor Design for Human Acetyl-coenzyme A Carboxylase by Interspecies Active Site Conversion

Synthesis of Unprotected Carboxy Indazoles via Pd-Catalyzed Carbonylation

Solid-Phase Synthesis of Benzopiperazinones

Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase Chemistry

Novel 2,2-dioxide-4,4-disubstituted-1,3-H-2,1,3-benzothiadiazines as non-nucleoside reverse transcriptase inhibitors

Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase

3,3a-Dihydropyrano[4,3,2-de]quinazolin-2(1H)-ones are potent non-nucleoside reverse transcriptase inhibitors

Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus

Inhibitors of Mammalian Acetyl-CoA Carboxylase

RECENT PROGRESS IN SOLID PHASE HETEROCYCLE SYNTHESES. A REVIEW

Designing glucokinase activators with reduced hypoglycemia risk: discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzo f uran-4-yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus

Discovery of second generation quinazolinone non-nucleoside reverse transcriptase inhibitors of HIV-1

3 Discovery of Second Generation Quinazolinone Non-Nucleoside Reverse Transcriptase Inhibitors of Hiv-1

The Stereochemical Course of Nucleophilic Additions of 2-Trialkylsiloxyfurans to Cyclic N-Acyliminium Ions

Solid-phase synthesis of a selective αvβ3 integrin antagonist library

Inhibitors of mammalian acetyl-CoA carboxylase

ChemInform Abstract: Trifluoromethyl-Containing 3-Alkoxymethyl- and 3-Aryloxymethyl-2-pyridinones Are Potent Inhibitors of HIV-1 Non-Nucleoside Reverse Transcriptase

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