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Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia

Nature medicine, 2007-06, Vol.13 (6), p.730-735

2007

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Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells

PloS one, 2016-03, Vol.11 (3), p.e0150450-e0150450

2016

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Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice

Blood, 2011-03, Vol.117 (9), p.2681-2690

2011

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The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells

Nature cell biology, 2010-12, Vol.12 (12), p.1213-1219

2010

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Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells

PloS one, 2018-03, Vol.13 (3), p.e0194913-e0194913

2018

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Defective in Mammary Gland Morphogenesis in Mice Lacking the Progesterone Receptor B Isoform

Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (17), p.9744-9749

2003

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Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice[S]

Journal of lipid research, 2013-03, Vol.54 (3), p.806-815

2013

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Deficiency of the NR4A Orphan Nuclear Receptor NOR1 Decreases Monocyte Adhesion and Atherosclerosis

Circulation research, 2010-08, Vol.107 (4), p.501-511

2010

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Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform

Science (American Association for the Advancement of Science), 2000-09, Vol.289 (5485), p.1751-1754

2000

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NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling

Blood, 2018-03, Vol.131 (10), p.1081-1093

2018

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Deficiency of the NR4A Neuron-Derived Orphan Receptor-1 Attenuates Neointima Formation After Vascular Injury

Circulation (New York, N.Y.), 2009-02, Vol.119 (4), p.577-586

2009

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The NR4A Orphan Nuclear Receptor NOR1 Is Induced by Platelet-derived Growth Factor and Mediates Vascular Smooth Muscle Cell Proliferation

The Journal of biological chemistry, 2006-11, Vol.281 (44), p.33467-33476

2006

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Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content

PloS one, 2014-02, Vol.9 (2), p.e89311-e89311

2014

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Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons

The European journal of neuroscience, 2003-10, Vol.18 (7), p.1731-1738

2003

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Lactoferrin and host defense

Biochemistry and cell biology, 2002, Vol.80 (1), p.95-102

2002

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nor-1 Regulates Hippocampal Axon Guidance, Pyramidal Cell Survival, and Seizure Susceptibility

Molecular and Cellular Biology, 2004-10, Vol.24 (20), p.9070-9078

2004

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Stimulus-Dependent Impairment of the Neutrophil Oxidative Burst Response in Lactoferrin-Deficient Mice

The American journal of pathology, 2008-04, Vol.172 (4), p.1019-1029

2008

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p53 is a Potential Mediator of Pregnancy and Hormone-Induced Resistance to Mammary Carcinogenesis

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (22), p.12379-12384

2001

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Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia

Nature medicine, 2007-06, Vol.13 (6), p.730-735

2007

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Drug targeting of NR4A nuclear receptors for treatment of acute myeloid leukemia

Leukemia, 2019-01, Vol.33 (1), p.52-63

2019

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Overlapping and Distinct Expression of Progesterone Receptors A and B in Mouse Uterus and Mammary Gland during the Estrous Cycle

Endocrinology (Philadelphia), 2006-12, Vol.147 (12), p.5503-5512

2006

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Iron Status in Mice Carrying a Targeted Disruption of Lactoferrin

Molecular and Cellular Biology, 2003-01, Vol.23 (1), p.178-185

2003

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Research Resource: Progesterone Receptor Targetome Underlying Mammary Gland Branching Morphogenesis

Molecular endocrinology (Baltimore, Md.), 2013-10, Vol.27 (10), p.1743-1761

2013

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Neuroendocrine Regulation of the Hypothalamic Pituitary Adrenal Axis by the nurr1/nur77 Subfamily of Nuclear Receptors

Molecular endocrinology (Baltimore, Md.), 1997-01, Vol.11 (1), p.39-47

1997

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Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors

Scientific reports, 2020-02, Vol.10 (1), p.2851, Article 2851

2020

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Abrogation of nuclear receptors Nr4a3 andNr4a1 leads to development of acute myeloid leukemia

Genome Wide Mapping of NR4A Binding Reveals Cooperativity with ETS Factors to Promote Epigenetic Activation of Distal Enhancers in Acute Myeloid Leukemia Cells

Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice

The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells

Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells

Defective in Mammary Gland Morphogenesis in Mice Lacking the Progesterone Receptor B Isoform

Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice[S]

Deficiency of the NR4A Orphan Nuclear Receptor NOR1 Decreases Monocyte Adhesion and Atherosclerosis

Subgroup of Reproductive Functions of Progesterone Mediated by Progesterone Receptor-B Isoform

NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling

Deficiency of the NR4A Neuron-Derived Orphan Receptor-1 Attenuates Neointima Formation After Vascular Injury

The NR4A Orphan Nuclear Receptor NOR1 Is Induced by Platelet-derived Growth Factor and Mediates Vascular Smooth Muscle Cell Proliferation

Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content

Involvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neurons

Lactoferrin and host defense

nor-1 Regulates Hippocampal Axon Guidance, Pyramidal Cell Survival, and Seizure Susceptibility

Stimulus-Dependent Impairment of the Neutrophil Oxidative Burst Response in Lactoferrin-Deficient Mice

p53 is a Potential Mediator of Pregnancy and Hormone-Induced Resistance to Mammary Carcinogenesis

Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia

Drug targeting of NR4A nuclear receptors for treatment of acute myeloid leukemia

Overlapping and Distinct Expression of Progesterone Receptors A and B in Mouse Uterus and Mammary Gland during the Estrous Cycle

Iron Status in Mice Carrying a Targeted Disruption of Lactoferrin

Research Resource: Progesterone Receptor Targetome Underlying Mammary Gland Branching Morphogenesis

Neuroendocrine Regulation of the Hypothalamic Pituitary Adrenal Axis by the nurr1/nur77 Subfamily of Nuclear Receptors

Targeting Oncogenic Super Enhancers in MYC-Dependent AML Using a Small Molecule Activator of NR4A Nuclear Receptors

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