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Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents

Current drug targets, 2017-01, Vol.18 (2), p.147-159

2017

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When should we order a next generation sequencing test in a patient with cancer?

EClinicalMedicine, 2020-08, Vol.25, p.100487-100487, Article 100487

2020

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FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1

Breast cancer research : BCR, 2021-02, Vol.23 (1), p.21-16, Article 21

2021

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Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

Nature communications, 2019-11, Vol.10 (1), p.5011-18, Article 5011

2019

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Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial

Breast cancer research : BCR, 2020-11, Vol.22 (1), p.124-124, Article 124

2020

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Nintedanib plus letrozole in early breast cancer: a phase 0/I pharmacodynamic, pharmacokinetic, and safety clinical trial of combined FGFR1 and aromatase inhibition

Breast cancer research : BCR, 2019-05, Vol.21 (1), p.69-14, Article 69

2019

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The Homologous Recombination Deficiency Scar in Advanced Cancer: Agnostic Targeting of Damaged DNA Repair

Cancers, 2022-06, Vol.14 (12), p.2950

2022

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Inhibition of Fatty Acid Synthase (FAS) Suppresses HER2/Neu (ErbB-2) Oncogene Overexpression in Cancer Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (29), p.10715-10720

2004

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A new role for circulating T follicular helper cells in humoral response to anti-PD-1 therapy

Journal for immunotherapy of cancer, 2020-09, Vol.8 (2), p.e001187

2020

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Effect of excess weight and immune-related adverse events on the efficacy of cancer immunotherapy with anti-PD-1 antibodies

Oncoimmunology, 2020-01, Vol.9 (1), p.1751548-1751548

2020

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Emotional Distress in Cancer Patients During the First Wave of the COVID-19 Pandemic

Frontiers in psychology, 2021-11, Vol.12, p.755965

2021

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Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells

BMC cancer, 2007-05, Vol.7 (1), p.80-80, Article 80

2007

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Peripheral Blood Mononuclear Cells Predict Therapeutic Efficacy of Immunotherapy in NSCLC

Cancers, 2022-06, Vol.14 (12), p.2898

2022

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Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity

Clinical cancer research, 2009-12, Vol.15 (24), p.7608-7615

2009

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BERENICE Final Analysis: Cardiac Safety Study of Neoadjuvant Pertuzumab, Trastuzumab, and Chemotherapy Followed by Adjuvant Pertuzumab and Trastuzumab in HER2-Positive Early Breast Cancer

Cancers, 2022-05, Vol.14 (11), p.2596

2022

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Antiangiogenics and Hypoxic Response: Role of Fatty Acid Synthase Inhibitors

Current drug targets, 2016-01, Vol.17 (15), p.1735-1746

2016

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A Single-Nucleotide Polymorphism in the Aromatase Gene Is Associated with the Efficacy of the Aromatase Inhibitor Letrozole in Advanced Breast Carcinoma

Clinical cancer research, 2008-02, Vol.14 (3), p.811-816

2008

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Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

Scientific reports, 2020-09, Vol.10 (1), p.14877-14877, Article 14877

2020

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Green Tea Catechin Inhibits Fatty Acid Synthase without Stimulating Carnitine Palmitoyltransferase-1 or Inducing Weight Loss in Experimental Animals

Anticancer research, 2008-11, Vol.28 (6A), p.3671-3676

2008

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A Fatty Acid Synthase Inhibitor Shows New Anticancer Mechanisms

EBioMedicine, 2015-08, Vol.2 (8), p.778-779

2015

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Intensive Loading Dose of Trastuzumab Achieves Higher-Than-Steady–State Serum Concentrations and Is Well Tolerated

Journal of clinical oncology, 2010-02, Vol.28 (6), p.960-966

2010

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Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant basal-HER2 subtype of breast cancer

Oncotarget, 2015-03, Vol.6 (9), p.7104-7122

2015

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Inhibition of tumor-associated fatty acid synthase hyperactivity induces synergistic chemosensitization of HER-2/neu-overexpressing human breast cancer cells to docetaxel (taxotere)

Breast cancer research and treatment, 2004-03, Vol.84 (2), p.183-195

2004

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Distribution of PD-L1, TROP2 and HER2- “lowness” in early triple-negative breast cancer: an opportunity for treatment de-escalation

Clinical & translational oncology, 2024-05, Vol.26 (5), p.1273-1279

2024

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The Pharmacological or Genetic Blockade of Endogenous De Novo Fatty Acid Synthesis Does Not Increase the Uptake of Exogenous Lipids in Ovarian Cancer Cells

Frontiers in oncology, 2021-04, Vol.11, p.610885-610885

2021

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Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents

When should we order a next generation sequencing test in a patient with cancer?

FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1

Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial

Nintedanib plus letrozole in early breast cancer: a phase 0/I pharmacodynamic, pharmacokinetic, and safety clinical trial of combined FGFR1 and aromatase inhibition

The Homologous Recombination Deficiency Scar in Advanced Cancer: Agnostic Targeting of Damaged DNA Repair

Inhibition of Fatty Acid Synthase (FAS) Suppresses HER2/Neu (ErbB-2) Oncogene Overexpression in Cancer Cells

A new role for circulating T follicular helper cells in humoral response to anti-PD-1 therapy

Effect of excess weight and immune-related adverse events on the efficacy of cancer immunotherapy with anti-PD-1 antibodies

Emotional Distress in Cancer Patients During the First Wave of the COVID-19 Pandemic

Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells

Peripheral Blood Mononuclear Cells Predict Therapeutic Efficacy of Immunotherapy in NSCLC

Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity

BERENICE Final Analysis: Cardiac Safety Study of Neoadjuvant Pertuzumab, Trastuzumab, and Chemotherapy Followed by Adjuvant Pertuzumab and Trastuzumab in HER2-Positive Early Breast Cancer

Antiangiogenics and Hypoxic Response: Role of Fatty Acid Synthase Inhibitors

A Single-Nucleotide Polymorphism in the Aromatase Gene Is Associated with the Efficacy of the Aromatase Inhibitor Letrozole in Advanced Breast Carcinoma

Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

Green Tea Catechin Inhibits Fatty Acid Synthase without Stimulating Carnitine Palmitoyltransferase-1 or Inducing Weight Loss in Experimental Animals

A Fatty Acid Synthase Inhibitor Shows New Anticancer Mechanisms

Intensive Loading Dose of Trastuzumab Achieves Higher-Than-Steady–State Serum Concentrations and Is Well Tolerated

Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant basal-HER2 subtype of breast cancer

Inhibition of tumor-associated fatty acid synthase hyperactivity induces synergistic chemosensitization of HER-2/neu-overexpressing human breast cancer cells to docetaxel (taxotere)

Distribution of PD-L1, TROP2 and HER2- “lowness” in early triple-negative breast cancer: an opportunity for treatment de-escalation

The Pharmacological or Genetic Blockade of Endogenous De Novo Fatty Acid Synthesis Does Not Increase the Uptake of Exogenous Lipids in Ovarian Cancer Cells

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