UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 113

Sortiert nach

Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Cancer research (Chicago, Ill.), 2009-08, Vol.69 (15), p.6232-6240

2009

Volltextzugriff (PDF)

Identification and Characterization of Acidic Mammalian Chitinase Inhibitors

Journal of medicinal chemistry, 2010-08, Vol.53 (16), p.6122-6128

2010

Volltextzugriff (PDF)

Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5209-5215

2017

Volltextzugriff (PDF)

Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2008-12, Vol.51 (23), p.7348-7351

2008

Volltextzugriff (PDF)

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT6 agonists

Bioorganic & medicinal chemistry, 2009-07, Vol.17 (14), p.5153-5163

2009

Volltextzugriff (PDF)

Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.7081-7089

2009

Volltextzugriff (PDF)

A Fragment-Based Approach to Identifying S‑Adenosyl‑l‑methionine -Competitive Inhibitors of Catechol O‑Methyl Transferase (COMT)

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5459-5463

2014

Volltextzugriff (PDF)

Facile Preparation of 1,2-Diketones

Synthetic communications, 2010-06, Vol.40 (14), p.2164-2171

2010

Volltextzugriff (PDF)

A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

Analytical biochemistry, 2010-04, Vol.399 (2), p.284-292

2010

Volltextzugriff (PDF)

Acylguanidines as Small-Molecule β-Secretase Inhibitors

Journal of medicinal chemistry, 2006-10, Vol.49 (21), p.6158-6161

2006

Volltextzugriff (PDF)

Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6 Receptor Agonists and Antagonists

Journal of medicinal chemistry, 2005-01, Vol.48 (2), p.353-356

2005

Volltextzugriff (PDF)

Modification of the swern oxidation: use of a recyclable, polystyrene bound sulfoxide

Bioorganic & medicinal chemistry letters, 2002-07, Vol.12 (14), p.1791-1793

2002

Volltextzugriff (PDF)

Inhibition of the Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway by 4-Oxo-1-Phenyl-1,4-Dihydroquinoline-3-Carboxylic Acid Esters

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4115-4121

2008

Volltextzugriff (PDF)

Synthesis and PKCθ inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3- b]pyridine-5-carbonitriles

Bioorganic & medicinal chemistry letters, 2008-05, Vol.18 (9), p.2850-2853

2008

Volltextzugriff (PDF)

Identification, Characterization and Initial Hit-to-Lead Optimization of a Series of 4-Arylamino-3-Pyridinecarbonitrile as Protein Kinase C theta (PKCθ) Inhibitors

Journal of medicinal chemistry, 2008-10, Vol.51 (19), p.5958-5963

2008

Volltextzugriff (PDF)

Acylguanidine inhibitors of β-secretase : Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (3), p.1063-1066

2008

Volltextzugriff (PDF)

Discovery of N1-(6-Chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a Potent, Selective, and Orally Active 5-HT6 Receptor Agonist

Journal of medicinal chemistry, 2007-11, Vol.50 (23), p.5535-5538

2007

Volltextzugriff (PDF)

Synthesis of Pyrazolo[1,5-α]pyrimidinone Regioisomers

Journal of organic chemistry, 2007-02, Vol.72 (3), p.1043-1046

2007

Volltextzugriff (PDF)

Discovery and initial optimization of 5,5′-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitors

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.632-635

2010

Volltextzugriff (PDF)

N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists

Bioorganic & medicinal chemistry letters, 2005, Vol.15 (2), p.379-383

2005

Volltextzugriff (PDF)

Identification of a new class of small molecule C5a receptor antagonists

Bioorganic & medicinal chemistry letters, 2010-01, Vol.20 (2), p.662-664

2010

Volltextzugriff (PDF)

Acylguanidine inhibitors of β-secretase : Optimization of the pyrrole ring substituents extending into the S'1 substrate binding pocket

Bioorganic & medicinal chemistry letters, 2008-01, Vol.18 (2), p.767-771

2008

Volltextzugriff (PDF)

Formation of Angularly-Fused Triquinanes by Successive Use of the Pauson-Khand Reaction and Radical Closure

Journal of organic chemistry, 1994-03, Vol.59 (6), p.1396-1406

1994

Volltextzugriff (PDF)

Silicon-Containing Amino Acids and Peptides. Asymmetric Synthesis of (Trialkylsilyl)alanines

Journal of organic chemistry, 1995-04, Vol.60 (8), p.2630-2634

1995

Volltextzugriff (PDF)

Design, Synthesis, and Biological Activity of a Potent Inhibitor of the Neuropeptidase N-Acetylated α-Linked Acidic Dipeptidase

Journal of medicinal chemistry, 1996-01, Vol.39 (2), p.619-622

1996

Volltextzugriff (PDF)

1 – 25 von 113

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(102)
Mit Volltextzugriff
(108)

Publikationsform

Sprache

Englisch
(112)
Japanisch
(18)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin

Identification and Characterization of Acidic Mammalian Chitinase Inhibitors

Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes

Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

Novel 1-aminoethyl-3-arylsulfonyl-1H-pyrrolo[2,3-b]pyridines are potent 5-HT6 agonists

Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase

A Fragment-Based Approach to Identifying S‑Adenosyl‑l‑methionine -Competitive Inhibitors of Catechol O‑Methyl Transferase (COMT)

Facile Preparation of 1,2-Diketones

A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

Acylguanidines as Small-Molecule β-Secretase Inhibitors

Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6 Receptor Agonists and Antagonists

Modification of the swern oxidation: use of a recyclable, polystyrene bound sulfoxide

Inhibition of the Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway by 4-Oxo-1-Phenyl-1,4-Dihydroquinoline-3-Carboxylic Acid Esters

Synthesis and PKCθ inhibitory activity of a series of 4-(indol-5-ylamino)thieno[2,3- b]pyridine-5-carbonitriles

Identification, Characterization and Initial Hit-to-Lead Optimization of a Series of 4-Arylamino-3-Pyridinecarbonitrile as Protein Kinase C theta (PKCθ) Inhibitors

Acylguanidine inhibitors of β-secretase : Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets

Discovery of N1-(6-Chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a Potent, Selective, and Orally Active 5-HT6 Receptor Agonist

Synthesis of Pyrazolo[1,5-α]pyrimidinone Regioisomers

Discovery and initial optimization of 5,5′-disubstituted aminohydantoins as potent β-secretase (BACE1) inhibitors

N1-arylsulfonyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives are potent and selective 5-HT6 receptor antagonists

Identification of a new class of small molecule C5a receptor antagonists

Acylguanidine inhibitors of β-secretase : Optimization of the pyrrole ring substituents extending into the S'1 substrate binding pocket

Formation of Angularly-Fused Triquinanes by Successive Use of the Pauson-Khand Reaction and Radical Closure

Silicon-Containing Amino Acids and Peptides. Asymmetric Synthesis of (Trialkylsilyl)alanines

Design, Synthesis, and Biological Activity of a Potent Inhibitor of the Neuropeptidase N-Acetylated α-Linked Acidic Dipeptidase

Suchergebnisse filtern