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Synthesis of Ethyl Pyrimidine-Quinolincarboxylates Selected from Virtual Screening as Enhanced Lactate Dehydrogenase (LDH) Inhibitors

International journal of molecular sciences, 2024-09, Vol.25 (17), p.9744

2024

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Structure activity relationships and the binding mode of quinolinone-pyrimidine hybrids as reversal agents of multidrug resistance mediated by P-gp

Scientific reports, 2021-08, Vol.11 (1), p.16856-18, Article 16856

2021

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Design and Synthesis of New Pyrimidine-Quinolone Hybrids as Novel hLDHA Inhibitors

Pharmaceuticals (Basel, Switzerland), 2022-06, Vol.15 (7), p.792

2022

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Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl)amino]chalcones and hydrazine as potential antitumor and antimalarial agents

European journal of medicinal chemistry, 2013-09, Vol.67, p.252-262

2013

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Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12589

2022

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Synthesis and in vitro antitumor activity of a novel series of 2-pyrazoline derivatives bearing the 4-aryloxy-7-chloroquinoline fragment

Molecules (Basel, Switzerland), 2014-11, Vol.19 (11), p.18656-18675

2014

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Regioselective Synthesis of Cycloalkane-fused Pyrazolo[4,3- e ]pyridines through Tandem Reaction of 5-aminopyrazoles, Cyclic Ketones and Electron-rich Olefins

Current organic synthesis, 2024-01, Vol.21 (7), p.947-956

2024

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Synthesis, Photophysical Properties, and Metal-Ion Recognition Studies of Fluoroionophores Based on 1‑(2-Pyridyl)-4-Styrylpyrazoles

ACS omega, 2019-10, Vol.4 (15), p.16689-16700

2019

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Ambient-Temperature Synthesis of (E)-N-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-1-(pyridin-2-yl)methanimine

MolBank, 2021-09, Vol.2021 (3), p.M1250

2021

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Straightforward synthesis of pyrimido[4,5-e][1,4]diazepines via 6-aminopyrimidin-5-carbaldehydes

Arabian journal of chemistry, 2019-12, Vol.12 (8), p.4579-4595

2019

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Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents

Molecules (Basel, Switzerland), 2018-02, Vol.23 (3), p.520

2018

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Microwave induced three-component synthesis and antimycobacterial activity of benzopyrazolo[3,4-b]quinolindiones

European journal of medicinal chemistry, 2014-03, Vol.74, p.216-224

2014

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Rosmarinic Acid Present in Lepechinia floribunda and Lepechinia meyenii as a Potent Inhibitor of the Adenylyl Cyclase gNC1 from Giardia lamblia

Plants (Basel), 2024-02, Vol.13 (5), p.646

2024

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Synthesis, anti-parasitic activity and QSAR study of a new library of polysubstituted tetrahydronaphtho[1,2-b]azepines

Medicinal chemistry research, 2018-10, Vol.27 (10), p.2239-2264

2018

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Three practical approaches for the synthesis of novel 4,7-dihetarylpyrazolo[1,5-a][1,3,5]triazines

Tetrahedron, 2012-11, Vol.68 (46), p.9384-9390

2012

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Synthesis, antifungal and antitumor activity of novel (Z)-5-hetarylmethylidene-1,3-thiazol-4-ones and (z)-5-ethylidene-1,3-thiazol-4-ones

Molecules (Basel, Switzerland), 2013-05, Vol.18 (5), p.5482-5497

2013

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Preparation of 6-chloropyrazolo[3,4- b]pyridine-5-carbaldehydes by Vilsmeier–Haack reaction and its use in the synthesis of heterocyclic chalcones and dipyrazolopyridines

Tetrahedron letters, 2010-05, Vol.51 (21), p.2928-2930

2010

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Synthesis of novel polysubstituted (2SR,4RS)-2-heteroaryltetrahydro-1,4-epoxy-1-benzazepines and cis-2-heteroaryl-4-hydroxytetrahydro-1H-1-benzazepines as antiparasitic agents

European journal of medicinal chemistry, 2014-10, Vol.86, p.291-309

2014

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Highly efficient and diastereoselective synthesis of new pyrazolylpyrrolizine and pyrazolylpyrrolidine derivates by a three-component domino process

Molecules (Basel, Switzerland), 2014-04, Vol.19 (4), p.4284-4300

2014

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Unexpected intramolecular cyclization of some 2′-aminochalcones to indolin-3-ones mediated by Amberlyst ®-15

Tetrahedron letters, 2008-08, Vol.49 (34), p.5028-5031

2008

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Computational and Experimental Study on Molecular Structure of Benzo[g]pyrimido[4,5-b]quinoline Derivatives: Preference of Linear over the Angular Isomer

Applied sciences, 2017-09, Vol.7 (10), p.967

2017

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Easy synthesis of new series of pteridine analogs: di- and tetra-hydropyrimido[4,5-d]pyrimidines via 5-pyrimidinecarbaldehydes

ARKIVOC, 2014-06, Vol.2014 (5), p.42-63

2014

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Ultrasonics Promoted Synthesis of 5-(Pyrazol-4-yl)-4,5-Dihydropyrazoles Derivatives

Applied sciences, 2013-06, Vol.3 (2), p.457-468

2013

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Synthesis and structural analysis of 1,4′-pyrazolo[3,4-e][1,4]thiazepin-7′(6H)ones: An example of conformational chirality in seven-membered heterocycles

Journal of molecular structure, 2025-02, Vol.1322, p.140380, Article 140380

2025

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Synthesis of novel quinoline-2-one based chalcones of potential anti-tumor activity

European journal of medicinal chemistry, 2012-11, Vol.57, p.29-40

2012

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Synthesis of Ethyl Pyrimidine-Quinolincarboxylates Selected from Virtual Screening as Enhanced Lactate Dehydrogenase (LDH) Inhibitors

Structure activity relationships and the binding mode of quinolinone-pyrimidine hybrids as reversal agents of multidrug resistance mediated by P-gp

Design and Synthesis of New Pyrimidine-Quinolone Hybrids as Novel hLDHA Inhibitors

Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl)amino]chalcones and hydrazine as potential antitumor and antimalarial agents

Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety

Synthesis and in vitro antitumor activity of a novel series of 2-pyrazoline derivatives bearing the 4-aryloxy-7-chloroquinoline fragment

Regioselective Synthesis of Cycloalkane-fused Pyrazolo[4,3- e ]pyridines through Tandem Reaction of 5-aminopyrazoles, Cyclic Ketones and Electron-rich Olefins

Synthesis, Photophysical Properties, and Metal-Ion Recognition Studies of Fluoroionophores Based on 1‑(2-Pyridyl)-4-Styrylpyrazoles

Ambient-Temperature Synthesis of (E)-N-(3-(tert-Butyl)-1-methyl-1H-pyrazol-5-yl)-1-(pyridin-2-yl)methanimine

Straightforward synthesis of pyrimido[4,5-e][1,4]diazepines via 6-aminopyrimidin-5-carbaldehydes

Design of Two Alternative Routes for the Synthesis of Naftifine and Analogues as Potential Antifungal Agents

Microwave induced three-component synthesis and antimycobacterial activity of benzopyrazolo[3,4-b]quinolindiones

Rosmarinic Acid Present in Lepechinia floribunda and Lepechinia meyenii as a Potent Inhibitor of the Adenylyl Cyclase gNC1 from Giardia lamblia

Synthesis, anti-parasitic activity and QSAR study of a new library of polysubstituted tetrahydronaphtho[1,2-b]azepines

Three practical approaches for the synthesis of novel 4,7-dihetarylpyrazolo[1,5-a][1,3,5]triazines

Synthesis, antifungal and antitumor activity of novel (Z)-5-hetarylmethylidene-1,3-thiazol-4-ones and (z)-5-ethylidene-1,3-thiazol-4-ones

Preparation of 6-chloropyrazolo[3,4- b]pyridine-5-carbaldehydes by Vilsmeier–Haack reaction and its use in the synthesis of heterocyclic chalcones and dipyrazolopyridines

Synthesis of novel polysubstituted (2SR,4RS)-2-heteroaryltetrahydro-1,4-epoxy-1-benzazepines and cis-2-heteroaryl-4-hydroxytetrahydro-1H-1-benzazepines as antiparasitic agents

Highly efficient and diastereoselective synthesis of new pyrazolylpyrrolizine and pyrazolylpyrrolidine derivates by a three-component domino process

Unexpected intramolecular cyclization of some 2′-aminochalcones to indolin-3-ones mediated by Amberlyst ®-15

Computational and Experimental Study on Molecular Structure of Benzo[g]pyrimido[4,5-b]quinoline Derivatives: Preference of Linear over the Angular Isomer

Easy synthesis of new series of pteridine analogs: di- and tetra-hydropyrimido[4,5-d]pyrimidines via 5-pyrimidinecarbaldehydes

Ultrasonics Promoted Synthesis of 5-(Pyrazol-4-yl)-4,5-Dihydropyrazoles Derivatives

Synthesis and structural analysis of 1,4′-pyrazolo[3,4-e][1,4]thiazepin-7′(6H)ones: An example of conformational chirality in seven-membered heterocycles

Synthesis of novel quinoline-2-one based chalcones of potential anti-tumor activity

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