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Bone metastasis: mechanisms, therapies, and biomarkers

Physiological reviews, 2021-07, Vol.101 (3), p.797-855

2021

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Bisphosphonates' antitumor activity: An unravelled side of a multifaceted drug class

Bone (New York, N.Y.), 2011-01, Vol.48 (1), p.71-79

Clezardin, Philippe

2011

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Tumor αvβ3 integrin is a therapeutic target for breast cancer bone metastases

Cancer research (Chicago, Ill.), 2007-06, Vol.67 (12), p.5821-5830

2007

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Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

Cancer research (Chicago, Ill.), 2007-09, Vol.67 (18), p.8742-8751

2007

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Bone-Targeted Therapies in Cancer-Induced Bone Disease

Calcified tissue international, 2018-02, Vol.102 (2), p.227-250

2018

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Pathophysiology of bone metastases from solid malignancies

Joint, bone, spine : revue du rhumatisme, 2017-12, Vol.84 (6), p.677-684

Clézardin, Philippe

2017

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High Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Promote Vγ9Vδ2 T-Cell Chemotaxis and Cytotoxicity In Vivo

Cancer research (Chicago, Ill.), 2011-07, Vol.71 (13), p.4562-4572

2011

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Direct and indirect anticancer activity of bisphosphonates: A brief review of published literature

Cancer treatment reviews, 2012-08, Vol.38 (5), p.407-415

2012

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Bisphosphonates and cancer-induced bone disease : Beyond their antiresorptive activity

Cancer research (Chicago, Ill.), 2005-06, Vol.65 (12), p.4971-4974

2005

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Rôle de la triade RANK/RANKL/ostéoprotégérine (OPG) dans les cancers primitifs et secondaires de l’os : aspects physiopathologiques et implications cliniques

Bulletin du cancer, 2011-07, Vol.98 (7), p.837-846

CLEZARDIN, Philippe

2011

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In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger Vγ9Vδ2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement

Clinical cancer research, 2012-11, Vol.18 (22), p.6249-6259

2012

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Physiopathologie des métastases osseuses et nouvelles cibles moléculaires impliquées dans le remodelage osseux

Bulletin du cancer, 2013-11, Vol.100 (11), p.1083-1091

CLEZARDIN, Philippe

2013

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Therapeutic targets for bone metastases in breast cancer

Breast cancer research : BCR, 2011-04, Vol.13 (2), p.207-207, Article 207

Clézardin, Philippe

2011

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Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer

The Journal of clinical investigation, 2004-12, Vol.114 (12), p.1714-1725

2004

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Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone

Oncotarget, 2016-11, Vol.7 (47), p.77071-77086

2016

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miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis-Associated Genes

Cancer research (Chicago, Ill.), 2018-09, Vol.78 (18), p.5259-5273

2018

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Cancer Cell Colonisation in the Bone Microenvironment

International journal of molecular sciences, 2016-10, Vol.17 (10), p.1674

2016

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Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions

Oncogene, 2021-02, Vol.40 (7), p.1284-1299

2021

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Mechanisms of action of bisphosphonates in oncology: a scientific concept evolving from antiresorptive to anticancer activities

BoneKEy reports, 2013-02, Vol.2, p.267-267

Clézardin, Philippe

2013

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Bone metastases

Nature reviews. Disease primers, 2020-10, Vol.6 (1), p.83, Article 83

2020

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Differential proteomic analysis of a human breast tumor and its matched bone metastasis identifies cell membrane and extracellular proteins associated with bone metastasis

Journal of proteome research, 2012-04, Vol.11 (4), p.2247-2260

2012

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The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases

Frontiers in oncology, 2020-02, Vol.10, p.69

2020

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The role of osteoclasts in breast cancer bone metastasis

Journal of bone oncology, 2016-09, Vol.5 (3), p.93-95

2016

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Lowering bone mineral affinity of bisphosphonates as a therapeutic strategy to optimize skeletal tumor growth inhibition in vivo

Cancer research (Chicago, Ill.), 2008-11, Vol.68 (21), p.8945-8953

2008

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A cathepsin K inhibitor reduces breast cancer-induced osteolysis and skeletal tumor burden

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (20), p.9894-9902

2007

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Bone metastasis: mechanisms, therapies, and biomarkers

Bisphosphonates' antitumor activity: An unravelled side of a multifaceted drug class

Tumor αvβ3 integrin is a therapeutic target for breast cancer bone metastases

Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

Bone-Targeted Therapies in Cancer-Induced Bone Disease

Pathophysiology of bone metastases from solid malignancies

High Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Promote Vγ9Vδ2 T-Cell Chemotaxis and Cytotoxicity In Vivo

Direct and indirect anticancer activity of bisphosphonates: A brief review of published literature

Bisphosphonates and cancer-induced bone disease : Beyond their antiresorptive activity

Rôle de la triade RANK/RANKL/ostéoprotégérine (OPG) dans les cancers primitifs et secondaires de l’os : aspects physiopathologiques et implications cliniques

In Vivo Phosphoantigen Levels in Bisphosphonate-Treated Human Breast Tumors Trigger Vγ9Vδ2 T-cell Antitumor Cytotoxicity through ICAM-1 Engagement

Physiopathologie des métastases osseuses et nouvelles cibles moléculaires impliquées dans le remodelage osseux

Therapeutic targets for bone metastases in breast cancer

Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone

miRNA-30 Family Members Inhibit Breast Cancer Invasion, Osteomimicry, and Bone Destruction by Directly Targeting Multiple Bone Metastasis-Associated Genes

Cancer Cell Colonisation in the Bone Microenvironment

Integrin alpha5 in human breast cancer is a mediator of bone metastasis and a therapeutic target for the treatment of osteolytic lesions

Mechanisms of action of bisphosphonates in oncology: a scientific concept evolving from antiresorptive to anticancer activities

Bone metastases

Differential proteomic analysis of a human breast tumor and its matched bone metastasis identifies cell membrane and extracellular proteins associated with bone metastasis

The CaSR in Pathogenesis of Breast Cancer: A New Target for Early Stage Bone Metastases

The role of osteoclasts in breast cancer bone metastasis

Lowering bone mineral affinity of bisphosphonates as a therapeutic strategy to optimize skeletal tumor growth inhibition in vivo

A cathepsin K inhibitor reduces breast cancer-induced osteolysis and skeletal tumor burden

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