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The biology of MDR1-P-glycoprotein (MDR1-Pgp) in designing functional antibody drug conjugates (ADCs): the experience of gemtuzumab ozogamicin

Annali dell'Istituto superiore di sanita, 2013-01, Vol.49 (2), p.150-168

CIANFRIGLIA, Maurizio

2013

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Targeting MDR1-P-glycoprotein (MDR1-Pgp) in immunochemotherapy of acute myeloid leukemia (AML)

Annali dell'Istituto superiore di sanita, 2013-01, Vol.49 (2), p.190-208

CIANFRIGLIA, Maurizio

2013

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Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases

BMC medicine, 2013-01, Vol.11 (1), p.4-4, Article 4

2013

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The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor

Blood cells, molecules, & diseases, 2010-06, Vol.45 (1), p.86-92

2010

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P-glycoprotein binds to ezrin at amino acid residues 149-242 in the FERM domain and plays a key role in the multidrug resistance of human osteosarcoma

International journal of cancer, 2012-06, Vol.130 (12), p.2824-2834

2012

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The expression and modulation of CEACAM1 and tumor cell transformation

Annali dell'Istituto superiore di sanita, 2012-01, Vol.48 (2), p.161-171

2012

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P-glycoprotein–actin association through ERM family proteins: a role in P-glycoprotein function in human cells of lymphoid origin

Blood, 2002-01, Vol.99 (2), p.641-648

2002

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6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1–mediated MDR in small cell lung cancer

Molecular cancer therapeutics, 2008-02, Vol.7 (2), p.371-379

2008

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Generation of human single-chain antibody to the CD99 cell surface determinant specifically recognizing Ewing's sarcoma tumor cells

Current pharmaceutical biotechnology, 2013-03, Vol.14 (4), p.449

2013

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Human brain tumors : multidrug-resistance P-glycoprotein expression in tumor cells and intratumoral capillary endothelial cells

Virchows Archiv : an international journal of pathology, 2007-07, Vol.451 (1), p.81-87

2007

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Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

BMC cancer, 2006-02, Vol.6 (1), p.41-41, Article 41

2006

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Generation and characterization of a human single-chain fragment variable (scFv) antibody against cytosine deaminase from yeast

BMC biotechnology, 2008-09, Vol.8 (1), p.68-68, Article 68

2008

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HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein

Retrovirology, 2007-03, Vol.4 (1), p.17-17

2007

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Generation of human scFvs antibodies recognizing a prion protein epitope expressed on the surface of human lymphoblastoid cells

BMC biotechnology, 2007-07, Vol.7 (1), p.38-38

2007

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Design and construction of a new human naïve single-chain fragment variable antibody library, IORISS1

Journal of biotechnology, 2016-04, Vol.224, p.1-11

2016

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Identification of a panel of tumor-associated antigens from breast carcinoma cell lines, solid tumors and testis cDNA libraries displayed on lambda phage

BMC cancer, 2004-11, Vol.4 (1), p.78-78, Article 78

2004

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Generation of human antibody fragments recognizing distinct epitopes of the nucleocapsid (N) SARS-CoV protein using a phage display approach

BMC infectious diseases, 2005-09, Vol.5 (1), p.73-73, Article 73

2005

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Multidrug transporter proteins and cellular factors involved in free and mAb linked calicheamicin-γ1 (gentuzumab ozogamicin, GO) resistance and in the selection of GO resistant variants of the HL60 AML cell line

International journal of oncology, 2010-04, Vol.36 (6)

Cianfriglia

2010

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CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

Clinical cancer research, 2015-01, Vol.21 (1), p.146-156

2015

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A Strong Glutathione S-Transferase Inhibitor Overcomes the P-glycoprotein-mediated Resistance in Tumor Cells

The Journal of biological chemistry, 2006-08, Vol.281 (33), p.23725-23732

2006

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The Multidrug Transporter P-Glycoprotein: A Mediator of Melanoma Invasion?

Journal of investigative dermatology, 2008-04, Vol.128 (4), p.957-971

2008

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Process development of a human recombinant diabody expressed in E. coli: engagement of CD99-induced apoptosis for target therapy in Ewing’s sarcoma

Applied microbiology and biotechnology, 2016-05, Vol.100 (9), p.3949-3963

2016

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Proapoptotic activity of new glutathione S-transferase inhibitors

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (9), p.3751-3761

2005

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The human antibody fragment DIATHIS1 specific for CEACAM1 enhances natural killer cell cytotoxicity against melanoma cell lines in vitro

Journal of immunotherapy (1997), 2015-11, Vol.38 (9), p.357

2015

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Blocking monocyte transmigration in in vitro system by a human antibody scFv anti-CD99. Efficient large scale purification from periplasmic inclusion bodies in E. coli expression system

Journal of immunological methods, 2014-06, Vol.408, p.35-45

2014

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The biology of MDR1-P-glycoprotein (MDR1-Pgp) in designing functional antibody drug conjugates (ADCs): the experience of gemtuzumab ozogamicin

Targeting MDR1-P-glycoprotein (MDR1-Pgp) in immunochemotherapy of acute myeloid leukemia (AML)

Clinical development of monoclonal antibody-based drugs in HIV and HCV diseases

The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor

P-glycoprotein binds to ezrin at amino acid residues 149-242 in the FERM domain and plays a key role in the multidrug resistance of human osteosarcoma

The expression and modulation of CEACAM1 and tumor cell transformation

P-glycoprotein–actin association through ERM family proteins: a role in P-glycoprotein function in human cells of lymphoid origin

6-(7-Nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol, a specific glutathione S-transferase inhibitor, overcomes the multidrug resistance (MDR)-associated protein 1–mediated MDR in small cell lung cancer

Generation of human single-chain antibody to the CD99 cell surface determinant specifically recognizing Ewing's sarcoma tumor cells

Human brain tumors : multidrug-resistance P-glycoprotein expression in tumor cells and intratumoral capillary endothelial cells

Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

Generation and characterization of a human single-chain fragment variable (scFv) antibody against cytosine deaminase from yeast

HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein

Generation of human scFvs antibodies recognizing a prion protein epitope expressed on the surface of human lymphoblastoid cells

Design and construction of a new human naïve single-chain fragment variable antibody library, IORISS1

Identification of a panel of tumor-associated antigens from breast carcinoma cell lines, solid tumors and testis cDNA libraries displayed on lambda phage

Generation of human antibody fragments recognizing distinct epitopes of the nucleocapsid (N) SARS-CoV protein using a phage display approach

Multidrug transporter proteins and cellular factors involved in free and mAb linked calicheamicin-γ1 (gentuzumab ozogamicin, GO) resistance and in the selection of GO resistant variants of the HL60 AML cell line

CD99 triggering in Ewing sarcoma delivers a lethal signal through p53 pathway reactivation and cooperates with doxorubicin

A Strong Glutathione S-Transferase Inhibitor Overcomes the P-glycoprotein-mediated Resistance in Tumor Cells

The Multidrug Transporter P-Glycoprotein: A Mediator of Melanoma Invasion?

Process development of a human recombinant diabody expressed in E. coli: engagement of CD99-induced apoptosis for target therapy in Ewing’s sarcoma

Proapoptotic activity of new glutathione S-transferase inhibitors

The human antibody fragment DIATHIS1 specific for CEACAM1 enhances natural killer cell cytotoxicity against melanoma cell lines in vitro

Blocking monocyte transmigration in in vitro system by a human antibody scFv anti-CD99. Efficient large scale purification from periplasmic inclusion bodies in E. coli expression system

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