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Mechanisms of deadenylation-dependent decay

Wiley interdisciplinary reviews. RNA, 2011-03, Vol.2 (2), p.167-183

2011

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Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

Nature structural & molecular biology, 2009-11, Vol.16 (11), p.1160-1166

2009

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Deadenylation Is Prerequisite for P-Body Formation and mRNA Decay in Mammalian Cells

The Journal of cell biology, 2008-07, Vol.182 (1), p.89-101

2008

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Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

Molecular cell, 2009-09, Vol.35 (6), p.868-880

2009

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Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding Protein-Dependent Positive Regulator of Cytoplasmic mRNA Deadenylation

Molecular and Cellular Biology, 2007-11, Vol.27 (22), p.7791-7801

2007

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Evidence Providing New Insights into TOB-Promoted Deadenylation and Supporting a Link between TOB's Deadenylation-Enhancing and Antiproliferative Activities

Molecular and Cellular Biology, 2012-03, Vol.32 (6), p.1089-1098

2012

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MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1

Nucleic acids research, 2016-05, Vol.44 (8), p.3772-3787

2016

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Emerging Themes in Regulation of Global mRNA Turnover in cis

Trends in biochemical sciences (Amsterdam. Regular ed.), 2017-01, Vol.42 (1), p.16-27

2017

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Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation

RNA (Cambridge), 2020-09, Vol.26 (9), p.1143-1159

2020

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ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression

Nucleic acids research, 2015-09, Vol.43 (15), p.7577-7589

2015

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Emerging mechanisms of mRNP remodeling regulation

Wiley interdisciplinary reviews. RNA, 2014-09, Vol.5 (5), p.713-722

2014

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The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

The EMBO journal, 1999-09, Vol.18 (18), p.4969-4980

1999

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UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant

Genes & development, 2004-08, Vol.18 (16), p.2010-2023

2004

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RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

The EMBO journal, 1998-06, Vol.17 (12), p.3461-3470

1998

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Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization

Molecular and Cellular Biology, 2002-10, Vol.22 (20), p.7268-7278

2002

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Rapid Deadenylation Triggered by a Nonsense Codon Precedes Decay of the RNA Body in a Mammalian Cytoplasmic Nonsense-Mediated Decay Pathway

Molecular and Cellular Biology, 2003-07, Vol.23 (14), p.4805-4813

2003

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Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation

Molecular and Cellular Biology, 2008-12, Vol.28 (24), p.7414-7426

2008

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Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

RNA (Cambridge), 2017-09, Vol.23 (9), p.1404-1418

2017

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BTG/TOB factors impact deadenylases

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-12, Vol.34 (12), p.640-647

2009

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Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

Nature structural & molecular biology, 2005-12, Vol.12 (12), p.1054-1063

2005

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Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay

Molecular and Cellular Biology, 1997-08, Vol.17 (8), p.4611-4621

1997

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Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation

RNA (Cambridge), 2011-09, Vol.17 (9), p.1619-1634

2011

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Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

RNA (Cambridge), 2013-03, Vol.19 (3), p.295-305

2013

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AU-rich elements: characterization and importance in mRNA degradation

Trends in Biochemical Sciences, 1995-11, Vol.20 (11), p.465-470

1995

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mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

Molecular and Cellular Biology, 1995-10, Vol.15 (10), p.5777-5788

1995

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Mechanisms of deadenylation-dependent decay

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

Deadenylation Is Prerequisite for P-Body Formation and mRNA Decay in Mammalian Cells

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding Protein-Dependent Positive Regulator of Cytoplasmic mRNA Deadenylation

Evidence Providing New Insights into TOB-Promoted Deadenylation and Supporting a Link between TOB's Deadenylation-Enhancing and Antiproliferative Activities

MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1

Emerging Themes in Regulation of Global mRNA Turnover in cis

Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression

Emerging mechanisms of mRNP remodeling regulation

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein

Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization

Rapid Deadenylation Triggered by a Nonsense Codon Precedes Decay of the RNA Body in a Mammalian Cytoplasmic Nonsense-Mediated Decay Pathway

Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

BTG/TOB factors impact deadenylases

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay

Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate

AU-rich elements: characterization and importance in mRNA degradation

mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

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