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Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist

The Journal of pharmacology and experimental therapeutics, 2003-03, Vol.304 (3), p.1093-1102

2003

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Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

The Journal of biological chemistry, 1999-04, Vol.274 (16), p.10689-10692

1999

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E5531, a Pure Endotoxin Antagonist of High Potency

Science (American Association for the Advancement of Science), 1995-04, Vol.268 (5207), p.80-83

1995

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Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

Vaccine, 2010-12, Vol.29 (1), p.104-114

2010

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Inhibition of endotoxin response by synthetic TLR4 antagonists

Current topics in medicinal chemistry, 2004-01, Vol.4 (11), p.1147-1171

2004

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3,3-Diaryl-1,3-dihydroindol-2-ones as Antiproliferatives Mediated by Translation Initiation Inhibition

Journal of medicinal chemistry, 2004-04, Vol.47 (8), p.1882-1885

2004

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Association of the Endotoxin Antagonist E5564 with High-Density Lipoproteins In Vitro: Dependence on Low-Density and Triglyceride-Rich Lipoprotein Concentrations

Antimicrobial Agents and Chemotherapy, 2003-09, Vol.47 (9), p.2796-2803

2003

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Consequences of Interaction of a Lipophilic Endotoxin Antagonist with Plasma Lipoproteins

Antimicrobial Agents and Chemotherapy, 2000-03, Vol.44 (3), p.504-510

2000

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Suppression of Murine Endotoxin Response by E5531, a Novel Synthetic Lipid A Antagonist

Antimicrobial Agents and Chemotherapy, 1998-11, Vol.42 (11), p.2824-2829

1998

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Total Synthesis of the Proposed Structure of Rhodobacter sphaeroides Lipid A Resulting in the Synthesis of New Potent Lipopolysaccharide Antagonists

Journal of the American Chemical Society, 1994-04, Vol.116 (8), p.3637-3638

1994

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Lipoprotein Distribution of a Novel Endotoxin Antagonist, E5531, in Plasma from Human Subjects with Various Lipid Levels

Antimicrobial Agents and Chemotherapy, 1999-10, Vol.43 (10), p.2562-2564

1999

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Total synthesis of palytoxin carboxylic acid and palytoxin amide

Journal of the American Chemical Society, 1989-09, Vol.111 (19), p.7530-7533

1989

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Total synthesis of a fully protected palytoxin carboxylic acid

Journal of the American Chemical Society, 1989-09, Vol.111 (19), p.7525-7530

1989

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CD11/CD18 and CD14 Share a Common Lipid A Signaling Pathway

The Journal of immunology (1950), 1998-11, Vol.161 (10), p.5413-5420

1998

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E5531, a synthetic non‐toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide

British journal of pharmacology, 1999-06, Vol.127 (4), p.853-862

1999

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Catalytic effect of nickel(II) chloride and palladium(II) acetate on chromium(II)-mediated coupling reaction of iodo olefins with aldehydes

Journal of the American Chemical Society, 1986-09, Vol.108 (18), p.5644-5646

1986

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Synthesis of fluorescein labeled 7-methylguanosinemonophosphate

Bioorganic & medicinal chemistry letters, 2004-05, Vol.14 (10), p.2657-2660

2004

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Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists

American journal of physiology. Lung cellular and molecular physiology, 2001-04, Vol.280 (4), p.771-L778

2001

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Lipopolysaccharide and Its Analog Antagonists Display Differential Serum Factor Dependencies for Induction of Cytokine Genes in Murine Macrophages

Infection and Immunity, 1998-06, Vol.66 (6), p.2562-2569

1998

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Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38

Bioorganic & medicinal chemistry letters, 2000-05, Vol.10 (10), p.1029-1032

2000

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Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists

Journal of medicinal chemistry, 1989-10, Vol.32 (10), p.2247-2254

1989

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Selective formation of C-2 azidodeoxy- d-glucose derivatives from d-glucal precursors using the azidonitration reaction

Carbohydrate research, 2000-08, Vol.328 (1), p.61-69

2000

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A practical synthesis of trans-iodoolefins

Tetrahedron letters, 1986, Vol.27 (39), p.4759-4762

1986

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Synthesis of lin-benzofervenulin, lin-benzotheophylline, and lin-benzocaffeine

Journal of organic chemistry, 1981-04, Vol.46 (8), p.1699-1702

1981

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Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists

American journal of physiology. Lung cellular and molecular physiology, 2001-04, Vol.24 (4), p.L771-L778

2001

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Inhibition of endotoxin response by e5564, a novel Toll-like receptor 4-directed endotoxin antagonist

Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction

E5531, a Pure Endotoxin Antagonist of High Potency

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

Inhibition of endotoxin response by synthetic TLR4 antagonists

3,3-Diaryl-1,3-dihydroindol-2-ones as Antiproliferatives Mediated by Translation Initiation Inhibition

Association of the Endotoxin Antagonist E5564 with High-Density Lipoproteins In Vitro: Dependence on Low-Density and Triglyceride-Rich Lipoprotein Concentrations

Consequences of Interaction of a Lipophilic Endotoxin Antagonist with Plasma Lipoproteins

Suppression of Murine Endotoxin Response by E5531, a Novel Synthetic Lipid A Antagonist

Total Synthesis of the Proposed Structure of Rhodobacter sphaeroides Lipid A Resulting in the Synthesis of New Potent Lipopolysaccharide Antagonists

Lipoprotein Distribution of a Novel Endotoxin Antagonist, E5531, in Plasma from Human Subjects with Various Lipid Levels

Total synthesis of palytoxin carboxylic acid and palytoxin amide

Total synthesis of a fully protected palytoxin carboxylic acid

CD11/CD18 and CD14 Share a Common Lipid A Signaling Pathway

E5531, a synthetic non‐toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide

Catalytic effect of nickel(II) chloride and palladium(II) acetate on chromium(II)-mediated coupling reaction of iodo olefins with aldehydes

Synthesis of fluorescein labeled 7-methylguanosinemonophosphate

Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists

Lipopolysaccharide and Its Analog Antagonists Display Differential Serum Factor Dependencies for Induction of Cytokine Genes in Murine Macrophages

Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38

Linear and proximal benzo-separated alkylated xanthines as adenosine-receptor antagonists

Selective formation of C-2 azidodeoxy- d-glucose derivatives from d-glucal precursors using the azidonitration reaction

A practical synthesis of trans-iodoolefins

Synthesis of lin-benzofervenulin, lin-benzotheophylline, and lin-benzocaffeine

Inhibition of LPS-induced airway hyperresponsiveness and airway inflammation by LPS antagonists

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