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Ligand-accelerated non-directed C–H functionalization of arenes

Nature (London), 2017-11, Vol.551 (7681), p.489-493

2017

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Catalytic Ring Expansions of Cyclic Alcohols Enabled by Proton-Coupled Electron Transfer

Journal of the American Chemical Society, 2019-06, Vol.141 (22), p.8752-8757

2019

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Structural and Thermal Characterization of Halogenated Azidopyridines: Under-Reported Synthons for Medicinal Chemistry

Organic letters, 2022-01, Vol.24 (3), p.799-803

2022

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The strength/weakness of the AJCC/UICC staging system (7th edition) for nasopharyngeal cancer and suggestions for future improvement

Oral oncology, 2012-10, Vol.48 (10), p.1007-1013

2012

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Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.15549-15581

2021

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Nickel-Catalyzed 1,2-Carboamination of Alkenyl Alcohols

Journal of the American Chemical Society, 2021-09, Vol.143 (34), p.13962-13970

2021

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A tautomeric ligand enables directed C‒H hydroxylation with molecular oxygen

Science (American Association for the Advancement of Science), 2021-06, Vol.372 (6549), p.1452-1457

2021

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Selective C−H Halogenation with a Highly Fluorinated Manganese Porphyrin

Angewandte Chemie International Edition, 2018-01, Vol.57 (5), p.1251-1255

International ed. in English, 2018

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Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis

Journal of the American Chemical Society, 2022-09, Vol.144 (38), p.17709-17720

2022

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Ligand-Promoted Borylation of C(sp3)H Bonds with Palladium(II) Catalysts

Angewandte Chemie (International ed.), 2016-01, Vol.55 (2), p.785-789

International ed. in English, 2016

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Alkene Difunctionalization Directed by Free Amines: Diamine Synthesis via Nickel-Catalyzed 1,2-Carboamination

ACS catalysis, 2022-04, Vol.12 (7), p.3890-3896

2022

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Manganese-Catalyzed Desaturation of N‑Acyl Amines and Ethers

ACS catalysis, 2019-10, Vol.9 (10), p.9513-9517

2019

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Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice

Diabetes (New York, N.Y.), 2006-01, Vol.55 (1), p.240-248

2006

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Discovery of azetidinone acids as conformationally-constrained dual PPARα/γ agonists

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1939-1944

2008

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Structural elucidation of human oxidative metabolites of muraglitazar: use of microbial bioreactors in the biosynthesis of metabolite standards

Drug metabolism and disposition, 2006-02, Vol.34 (2), p.267-280

2006

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Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling

Drug metabolism and disposition, 2007-01, Vol.35 (1), p.150-167

2007

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Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (21), p.5928-5933

2007

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Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)‑1H‑pyrazol-1-yl)methyl)phosphonate (BMS-820132)

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.4291-4317

2022

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Ligand-Promoted Borylation of C(sp3)H Bonds with Palladium(II) Catalysts

Angewandte Chemie, 2016-01, Vol.128 (2), p.795-799

2016

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Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites

Drug metabolism and disposition, 2006-05, Vol.34 (5), p.807-820

2006

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Utilization of the Zucker Diabetic Fatty (ZDF) Rat Model for Investigating Hypoglycemia-related Toxicities

Toxicologic pathology, 2015-08, Vol.43 (6), p.825-837

2015

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Major Late Toxicities After Conformal Radiotherapy for Nasopharyngeal Carcinoma—Patient- and Treatment-Related Risk Factors

International journal of radiation oncology, biology, physics, 2009-03, Vol.73 (4), p.1121-1128

2009

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Ligand-accelerated non-directed C–H functionalization of arenes

Catalytic Ring Expansions of Cyclic Alcohols Enabled by Proton-Coupled Electron Transfer

Structural and Thermal Characterization of Halogenated Azidopyridines: Under-Reported Synthons for Medicinal Chemistry

The strength/weakness of the AJCC/UICC staging system (7th edition) for nasopharyngeal cancer and suggestions for future improvement

Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases

Nickel-Catalyzed 1,2-Carboamination of Alkenyl Alcohols

A tautomeric ligand enables directed C‒H hydroxylation with molecular oxygen

Selective C−H Halogenation with a Highly Fluorinated Manganese Porphyrin

Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities

Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis

Ligand-Promoted Borylation of C(sp3)H Bonds with Palladium(II) Catalysts

Alkene Difunctionalization Directed by Free Amines: Diamine Synthesis via Nickel-Catalyzed 1,2-Carboamination

Manganese-Catalyzed Desaturation of N‑Acyl Amines and Ethers

Muraglitazar, a Novel Dual (α/γ) Peroxisome Proliferator–Activated Receptor Activator, Improves Diabetes and Other Metabolic Abnormalities and Preserves β-Cell Function in db/db Mice

Discovery and Preclinical Evaluation of BMS-711939, an Oxybenzylglycine Based PPARα Selective Agonist

Discovery of azetidinone acids as conformationally-constrained dual PPARα/γ agonists

Discovery of a Tetrazole-Based Growth Hormone Secretagogue: 4-(Hydroxybutyl)carbamic Acid 2-{5-[1-(2-Amino-2-methylpropionylamino)-2- benzyloxyethyl]tetrazol-1-yl}ethyl Ester (BMS-317180)

Structural elucidation of human oxidative metabolites of muraglitazar: use of microbial bioreactors in the biosynthesis of metabolite standards

Comparative metabolism of radiolabeled muraglitazar in animals and humans by quantitative and qualitative metabolite profiling

Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues

Discovery of a Partial Glucokinase Activator Clinical Candidate: Diethyl ((3-(3-((5-(Azetidine-1-carbonyl)pyrazin-2-yl)oxy)-5-isopropoxybenzamido)‑1H‑pyrazol-1-yl)methyl)phosphonate (BMS-820132)

Ligand-Promoted Borylation of C(sp3)H Bonds with Palladium(II) Catalysts

Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites

Utilization of the Zucker Diabetic Fatty (ZDF) Rat Model for Investigating Hypoglycemia-related Toxicities

Major Late Toxicities After Conformal Radiotherapy for Nasopharyngeal Carcinoma—Patient- and Treatment-Related Risk Factors

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