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Azapeptides -A History of Synthetic Milestones and Key Examples

Current medicinal chemistry, 2022-12, Vol.29 (42), p.6336-6358

2022

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Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo

Molecular cancer therapeutics, 2008-03, Vol.7 (3), p.510-520

2008

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Phenolic Hydrazones Are Potent Inhibitors of Macrophage Migration Inhibitory Factor Proinflammatory Activity and Survival Improving Agents in Sepsis

Journal of medicinal chemistry, 2007-04, Vol.50 (8), p.1993-1997

2007

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Alternative Chemical Modifications Reverse the Binding Orientation of a Pharmacophore Scaffold in the Active Site of Macrophage Migration Inhibitory Factor

The Journal of biological chemistry, 2007-08, Vol.282 (32), p.23089-23095

2007

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Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation

Molecular medicine (Cambridge, Mass.), 2019-04, Vol.25 (1), p.13-13, Article 13

2019

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Thiocarbazate building blocks enable the construction of azapeptides for rapid development of therapeutic candidates

Nature communications, 2022-11, Vol.13 (1), p.7127-7127, Article 7127

2022

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Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (25), p.10255-10259

2011

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Novel inhibitors of macrophage migration inhibitory factor prevent cytokine-induced beta cell death

European journal of pharmacology, 2014-10, Vol.740, p.683-689

2014

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ISO-66, a novel inhibitor of macrophage migration inhibitory factor, shows efficacy in melanoma and colon cancer models

International journal of oncology, 2014-10, Vol.45 (4), p.1457-1468

2014

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Macrophage migration inhibitory factor mediates hypoxia-induced pulmonary hypertension

Molecular medicine (Cambridge, Mass.), 2012, Vol.18 (2), p.215-223

2012

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Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity

Proceedings of the National Academy of Sciences - PNAS, 2011-05, Vol.108 (20), p.8224-8227

2011

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Critical modifications of the ISO-1 scaffold improve its potent inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (13), p.3376-3379

2006

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The antitumor properties of a nontoxic, nitric oxide–modified version of saquinavir are independent of Akt

Molecular cancer therapeutics, 2009-05, Vol.8 (5), p.1169-1178

2009

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A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production

The Journal of immunology (1950), 2014-12, Vol.193 (12), p.5904-5913

2014

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Tessellation of Porphyrazines with Porphyrins by Design

Inorganic chemistry, 2006-08, Vol.45 (17), p.6928-6932

2006

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Real-time Simulation of Gas Based on Smoothed Particle Hydrodynamics

计算机辅助绘图设计与制造（英文版）, 2015, Vol.25 (1), p.68-73

ZHU Xiao-lin FAN Cheng-kai LIU Yang-yang

2015

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Porphyrins Linked Directly to the 5,5‘ Positions of 2,2‘-Bipyridine: A New Supramolecular Building Block and Switch

Inorganic chemistry, 2003-03, Vol.42 (6), p.2075-2083

2003

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Determinants of health-related quality of life after out-of-hospital cardiac arrest (OHCA): A systematic review

Resuscitation, 2023-07, Vol.188, p.109794-109794, Article 109794

2023

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Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential

The Journal of biological chemistry, 2016-12, Vol.291 (51), p.26502-26514

2016

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Endogenous retroviruses are associated with hippocampus-based memory impairment

Proceedings of the National Academy of Sciences - PNAS, 2019-12, Vol.116 (51), p.25982-25990

2019

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A structural investigation of FISLE-412, a peptidomimetic compound derived from saquinavir that targets lupus autoantibodies

Bioorganic & medicinal chemistry letters, 2017-10, Vol.27 (20), p.4725-4729

2017

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β‐Hydroxy‐tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE‐412

Chemistry : a European journal, 2017-08, Vol.23 (45), p.10738-10743

2017

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[beta]-Hydroxy-tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE-412

Chemistry : a European journal, 2017-08, Vol.23 (45), p.10738

2017

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Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation

Brain, behavior, and immunity, 2015-02, Vol.44, p.19-27

2015

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A novel mechanism of B-cell mediated immune suppression through adenosine production (P1084)

The Journal of immunology (1950), 2013-05, Vol.190 (1_Supplement), p.185-185.16

2013

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Azapeptides -A History of Synthetic Milestones and Key Examples

Anticancer properties of the novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide in vitro and in vivo

Phenolic Hydrazones Are Potent Inhibitors of Macrophage Migration Inhibitory Factor Proinflammatory Activity and Survival Improving Agents in Sepsis

Alternative Chemical Modifications Reverse the Binding Orientation of a Pharmacophore Scaffold in the Active Site of Macrophage Migration Inhibitory Factor

Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation

Thiocarbazate building blocks enable the construction of azapeptides for rapid development of therapeutic candidates

Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity

Novel inhibitors of macrophage migration inhibitory factor prevent cytokine-induced beta cell death

ISO-66, a novel inhibitor of macrophage migration inhibitory factor, shows efficacy in melanoma and colon cancer models

Macrophage migration inhibitory factor mediates hypoxia-induced pulmonary hypertension

Thyroxine is a potential endogenous antagonist of macrophage migration inhibitory factor (MIF) activity

Critical modifications of the ISO-1 scaffold improve its potent inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity

The antitumor properties of a nontoxic, nitric oxide–modified version of saquinavir are independent of Akt

A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production

Tessellation of Porphyrazines with Porphyrins by Design

Real-time Simulation of Gas Based on Smoothed Particle Hydrodynamics

Porphyrins Linked Directly to the 5,5‘ Positions of 2,2‘-Bipyridine: A New Supramolecular Building Block and Switch

Determinants of health-related quality of life after out-of-hospital cardiac arrest (OHCA): A systematic review

Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential

Endogenous retroviruses are associated with hippocampus-based memory impairment

A structural investigation of FISLE-412, a peptidomimetic compound derived from saquinavir that targets lupus autoantibodies

β‐Hydroxy‐tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE‐412

[beta]-Hydroxy-tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE-412

Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation

A novel mechanism of B-cell mediated immune suppression through adenosine production (P1084)

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