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Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8 + T cell exhaustion

Nature communications, 2020-09, Vol.11 (1), p.4520-4520, Article 4520

2020

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Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers

Nature communications, 2021-05, Vol.12 (1), p.2606-2606, Article 2606

2021

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Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of Oral Squamous Cell Carcinoma

Cancer prevention research (Philadelphia, Pa.), 2021-03, Vol.14 (3), p.313-324

2021

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Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance

Frontiers in immunology, 2023-06, Vol.14, p.1161869-1161869

2023

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An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation

Journal of leukocyte biology, 2014-01, Vol.95 (1), p.139-148

2014

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In vitro inhibition of translation initiation by N,N′-diarylureas—potential anti-cancer agents

Bioorganic & medicinal chemistry letters, 2012-01, Vol.22 (1), p.402-409

2012

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Overexpression of CXC Chemokine Ligand 14 Exacerbates Collagen-Induced Arthritis

The Journal of immunology (1950), 2010-04, Vol.184 (8), p.4455-4459

2010

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Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

Cancer discovery, 2019-05, Vol.9 (5), p.646-661

2019

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CD38 as an immunomodulator in cancer

Future oncology (London, England), 2020-12, Vol.16 (34), p.2853-2861

2020

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Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

Clinical cancer research, 2016-07, Vol.22 (14), p.3630-3642

2016

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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

Nature communications, 2014-10, Vol.5 (1), p.5241-5241, Article 5241

2014

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γ-Glutamyl cyclotransferase contributes to tumor progression in high grade serous ovarian cancer by regulating epithelial-mesenchymal transition via activating PI3K/AKT/mTOR pathway

Gynecologic oncology, 2018-04, Vol.149 (1), p.163-172

2018

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Targeting CD38 to improve anti-PD-1/CTLA-4 combination therapy in lung cancer

Journal of clinical oncology, 2018-02, Vol.36 (5_suppl), p.144-144

2018

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Role of symmetry in 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as inhibitors of translation initiation

Bioorganic & medicinal chemistry letters, 2023-01, Vol.80, p.129119-129119, Article 129119

2023

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CD38 as a novel immune checkpoint and a mechanism of resistance to the blockade of the PD-1/PD-L1 axis

Journal of clinical oncology, 2017-03, Vol.35 (7_suppl), p.79-79

2017

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Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target

Nature chemical biology, 2011-09, Vol.7 (9), p.610-616

2011

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Synthesis of Rigidified eIF4E/eIF4G Inhibitor‑1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5094-5111

2014

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Abstract A05: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis

Cancer research (Chicago, Ill.), 2016-04, Vol.76 (7_Supplement), p.A05-A05

2016

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Abstract PR01: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis

Cancer research (Chicago, Ill.), 2016-04, Vol.76 (7_Supplement), p.PR01-PR01

2016

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Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway

Oncology reports, 2015-10, Vol.34 (4), p.1787-1794

2015

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Abstract A108: DNA damage repair targeting upregulates PD-L1 level and potentiates the effect of PD-L1 blockade in small cell lung cancer

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.A108-A108

2018

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Abstract 567: CD38 blockade overcomes the immune resistance to anti-PD-L1 therapy by boosting CD8 T cell response

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.567-567

2017

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3-Substituted Indazoles as Configurationally Locked 4EGI-1 Mimetics and Inhibitors of the eIF4E/eIF4G Interaction

Chembiochem : a European journal of chemical biology, 2014-03, Vol.15 (4), p.595-611

2014

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KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1

Oncotarget, 2015-10, Vol.6 (31), p.31702-31720

2015

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Collagen promotes anti-PD-1/PD-L1 resistance in cancer through LAIR1-dependent CD8 + T cell exhaustion

Th17 cells contribute to combination MEK inhibitor and anti-PD-L1 therapy resistance in KRAS/p53 mutant lung cancers

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

Targeting of CD40 and PD-L1 Pathways Inhibits Progression of Oral Premalignant Lesions in a Carcinogen-induced Model of Oral Squamous Cell Carcinoma

Targeting immunosuppressive Ly6C+ classical monocytes reverses anti-PD-1/CTLA-4 immunotherapy resistance

An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation

In vitro inhibition of translation initiation by N,N′-diarylureas—potential anti-cancer agents

Overexpression of CXC Chemokine Ligand 14 Exacerbates Collagen-Induced Arthritis

Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer

CD38 as an immunomodulator in cancer

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression

γ-Glutamyl cyclotransferase contributes to tumor progression in high grade serous ovarian cancer by regulating epithelial-mesenchymal transition via activating PI3K/AKT/mTOR pathway

Targeting CD38 to improve anti-PD-1/CTLA-4 combination therapy in lung cancer

Role of symmetry in 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as inhibitors of translation initiation

CD38 as a novel immune checkpoint and a mechanism of resistance to the blockade of the PD-1/PD-L1 axis

Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target

Synthesis of Rigidified eIF4E/eIF4G Inhibitor‑1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction

Abstract A05: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis

Abstract PR01: Targeting the EMT-immunosuppression loop in lung cancer as a strategy to prevent metastasis

Twist induces epithelial-mesenchymal transition in cervical carcinogenesis by regulating the TGF-β/Smad3 signaling pathway

Abstract A108: DNA damage repair targeting upregulates PD-L1 level and potentiates the effect of PD-L1 blockade in small cell lung cancer

Abstract 567: CD38 blockade overcomes the immune resistance to anti-PD-L1 therapy by boosting CD8 T cell response

3-Substituted Indazoles as Configurationally Locked 4EGI-1 Mimetics and Inhibitors of the eIF4E/eIF4G Interaction

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1

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