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A Phase 1 Pharmacokinetic and Pharmacodynamic Study of the Histone Deacetylase Inhibitor Belinostat in Patients with Advanced Solid Tumors

Clinical cancer research, 2008-02, Vol.14 (3), p.804-810

2008

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First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers

Journal for immunotherapy of cancer, 2020-06, Vol.8 (1)

2020

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ADP-Ribosylation Factor 1 (ARF1) Regulates Recruitment of the AP-3 Adaptor Complex to Membranes

The Journal of cell biology, 1998-07, Vol.142 (2), p.391-402

1998

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Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet

The EMBO journal, 1997-08, Vol.16 (15), p.4508-4518

1997

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Efficacy and Safety of E7777 (improved purity Denileukin diftitox [ONTAK]) in Patients with Relapsed or Refractory Cutaneous T-Cell Lymphoma: Results from Pivotal Study 302

Blood, 2022-11, Vol.140 (Supplement 1), p.1491-1492

2022

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Safety and Tolerability of E7777 (improved purity Denileukin diftitox [ONTAK]) in Patients with Relapsed or Refractory Cutaneous T-Cell Lymphoma: Results from Pivotal Study 302

Blood, 2022-11, Vol.140 (Supplement 1), p.6577-6578

2022

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An Ear-Core Interaction Regulates the Recruitment of the AP-3 Complex to Membranes

Developmental cell, 2004-10, Vol.7 (4), p.619-625

2004

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Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils

The Journal of experimental medicine, 1991-09, Vol.174 (3), p.649-655

1991

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A phase I clinical trial of the histone deacetylase inhibitor belinostat in patients with advanced hematological neoplasia

European journal of haematology, 2008-09, Vol.81 (3), p.170-176

2008

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Phase 1 study of E7046, an inhibitor of the PGE 2 receptor EP-4, that targets immunosuppressive myeloid cells in the tumor microenvironment (NCT02540291)

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.e14116-e14116

2016

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First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE 2 -receptor E-type 4 (EP4), in patients with advanced cancers

Journal for immunotherapy of cancer, 2020-06, Vol.8 (1), p.e000222

2020

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Bidirectional movement of a nascent polypeptide across microsomal membranes reveals requirements for vectorial translocation of proteins

Cell, 1992-10, Vol.71 (1), p.87-96

1992

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Phase I study of E7046, a novel PGE 2 receptor type 4 inhibitor, in patients with advanced solid tumors: Clinical results and effects on myeloid- and T-lymphoid cell-mediated immunosuppression

Journal of clinical oncology, 2018-02, Vol.36 (5_suppl), p.49-49

2018

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A Dose Finding Lead-in Study of E7777 (Diphtheria toxin fragment-Interleukin-2 Fusion Protein) in Persistent or Recurrent Cutaneous T-Cell Lymphoma (CTCL)

Blood, 2014-12, Vol.124 (21), p.3097-3097

2014

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Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins

The Journal of biological chemistry, 1993-03, Vol.268 (8), p.6058-6063

1993

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β3A-adaptin, a Subunit of the Adaptor-like Complex AP-3

The Journal of biological chemistry, 1997-06, Vol.272 (24), p.15078-15084

1997

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AP-3: an adaptor-like protein complex with ubiquitous expression

The EMBO journal, 1997-03, Vol.16 (5), p.917-928

1997

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Overexpression of Wild-Type and Mutant ARF1 and ARF6: Distinct Perturbations of Nonoverlapping Membrane Compartments

The Journal of cell biology, 1995-03, Vol.128 (6), p.1003-1017

1995

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Copper-dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis

The EMBO journal, 1996-07, Vol.15 (14), p.3515-3523

1996

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beta 3A-adaptin, a subunit of the adaptor-like complex AP-3

The Journal of biological chemistry, 1997-06, Vol.272 (24), p.15078-15084

1997

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A Phase II Study of PXD101 in Advanced Multiple Myeloma

Blood, 2006-11, Vol.108 (11), p.3583-3583

2006

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Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli

The Journal of clinical investigation, 1994-08, Vol.94 (2), p.672-682

1994

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Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations

The Journal of biological chemistry, 1989-06, Vol.264 (16), p.9505-9509

1989

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Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate

The Journal of biological chemistry, 1990-04, Vol.265 (12), p.6675-6681

1990

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Antibacterial proteins of granulocytes differ in interaction with endotoxin. Comparison of bactericidal/permeability-increasing protein, p15s, and defensins

The Journal of immunology (1950), 1995-05, Vol.154 (10), p.5403

1995

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A Phase 1 Pharmacokinetic and Pharmacodynamic Study of the Histone Deacetylase Inhibitor Belinostat in Patients with Advanced Solid Tumors

First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers

ADP-Ribosylation Factor 1 (ARF1) Regulates Recruitment of the AP-3 Adaptor Complex to Membranes

Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet

Efficacy and Safety of E7777 (improved purity Denileukin diftitox [ONTAK]) in Patients with Relapsed or Refractory Cutaneous T-Cell Lymphoma: Results from Pivotal Study 302

Safety and Tolerability of E7777 (improved purity Denileukin diftitox [ONTAK]) in Patients with Relapsed or Refractory Cutaneous T-Cell Lymphoma: Results from Pivotal Study 302

An Ear-Core Interaction Regulates the Recruitment of the AP-3 Complex to Membranes

Endotoxin-neutralizing properties of the 25 kD N-terminal fragment and a newly isolated 30 kD C-terminal fragment of the 55-60 kD bactericidal/permeability-increasing protein of human neutrophils

A phase I clinical trial of the histone deacetylase inhibitor belinostat in patients with advanced hematological neoplasia

Phase 1 study of E7046, an inhibitor of the PGE 2 receptor EP-4, that targets immunosuppressive myeloid cells in the tumor microenvironment (NCT02540291)

First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE 2 -receptor E-type 4 (EP4), in patients with advanced cancers

Bidirectional movement of a nascent polypeptide across microsomal membranes reveals requirements for vectorial translocation of proteins

Phase I study of E7046, a novel PGE 2 receptor type 4 inhibitor, in patients with advanced solid tumors: Clinical results and effects on myeloid- and T-lymphoid cell-mediated immunosuppression

A Dose Finding Lead-in Study of E7777 (Diphtheria toxin fragment-Interleukin-2 Fusion Protein) in Persistent or Recurrent Cutaneous T-Cell Lymphoma (CTCL)

Antibacterial 15-kDa protein isoforms (p15s) are members of a novel family of leukocyte proteins

β3A-adaptin, a Subunit of the Adaptor-like Complex AP-3

AP-3: an adaptor-like protein complex with ubiquitous expression

Overexpression of Wild-Type and Mutant ARF1 and ARF6: Distinct Perturbations of Nonoverlapping Membrane Compartments

Copper-dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis

beta 3A-adaptin, a subunit of the adaptor-like complex AP-3

A Phase II Study of PXD101 in Advanced Multiple Myeloma

Individual and synergistic effects of rabbit granulocyte proteins on Escherichia coli

Cloning of the cDNA of a human neutrophil bactericidal protein. Structural and functional correlations

Purification of a cellular (granulocyte) and an extracellular (serum) phospholipase A2 that participate in the destruction of Escherichia coli in a rabbit inflammatory exudate

Antibacterial proteins of granulocytes differ in interaction with endotoxin. Comparison of bactericidal/permeability-increasing protein, p15s, and defensins

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