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RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis

International journal of molecular sciences, 2021-11, Vol.22 (21), p.11870

2021

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TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

Nature communications, 2020-01, Vol.11 (1), p.341-341, Article 341

2020

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Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models

PloS one, 2011-08, Vol.6 (8), p.e22924

2011

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Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology

Journal of biomedical science, 2018-11, Vol.25 (1), p.76-76, Article 76

2018

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A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis

International journal of molecular sciences, 2021-07, Vol.22 (15), p.8024

2021

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Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (37), p.15024-15029

2012

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TDP-43 Regulates Coupled Dendritic mRNA Transport-Translation Processes in Co-operation with FMRP and Staufen1

Cell reports (Cambridge), 2019-12, Vol.29 (10), p.3118-3133.e6

2019

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The Mammalian de Novo DNA Methyltransferases DNMT3A and DNMT3B Are Also DNA 5-Hydroxymethylcytosine Dehydroxymethylases

The Journal of biological chemistry, 2012-09, Vol.287 (40), p.33116-33121

2012

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Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP

Acta neuropathologica, 2016-11, Vol.132 (5), p.721-738

2016

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Phosphorylation-dependent SUMOylation of the transcription factor NF-E2

PloS one, 2012-09, Vol.7 (9), p.e44608-e44608

2012

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DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

The Journal of biological chemistry, 2013-03, Vol.288 (13), p.9084-9091

2013

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Structural insights into TDP-43 in nucleic-acid binding and domain interactions

Nucleic acids research, 2009-04, Vol.37 (6), p.1799-1808

2009

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Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Journal of cell science, 2014-07, Vol.127 (Pt 14), p.3024-3038

2014

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Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease

Human molecular genetics, 2015-03, Vol.24 (6), p.1602-1616

2015

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A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568

Science (American Association for the Advancement of Science), 2017-05, Vol.356 (6339), p.757-760

2017

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Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U

The Journal of experimental medicine, 2010-08, Vol.207 (8), p.1661-1673

2010

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Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage

PloS one, 2012-10, Vol.7 (10), p.e47481-e47481

2012

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Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS

Journal of biomedical science, 2016-10, Vol.23 (1), p.72-72, Article 72

2016

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A robust TDP-43 knock-in mouse model of ALS

Acta neuropathologica communications, 2020-01, Vol.8 (1), p.3-3, Article 3

2020

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Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease

European journal of medicinal chemistry, 2021-01, Vol.209, p.112938-112938, Article 112938

2021

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Autophagy activation ameliorates neuronal pathogenesis of FTLD-U mice: A new light for treatment of TARDBP/TDP-43 proteinopathies

Autophagy, 2013-02, Vol.9 (2), p.239-240

2013

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G-CSF rescues the memory impairment of animal models of Alzheimer's disease

The Journal of experimental medicine, 2007-06, Vol.204 (6), p.1273-1280

2007

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Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells

Molecular and cellular biology, 2015-07, Vol.35 (14), p.2541-2553

2015

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Negative Regulation of the Differentiation of Flk2 - CD34 - LSK Hematopoietic Stem Cells by EKLF/KLF1

International journal of molecular sciences, 2020-11, Vol.21 (22), p.8448

2020

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TDP-43 regulates the mammalian spinogenesis through translational repression of Rac1

Acta neuropathologica, 2012-08, Vol.124 (2), p.231-245

2012

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RNA Modifications and RNA Metabolism in Neurological Disease Pathogenesis

TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models

Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology

A Positive Regulatory Feedback Loop between EKLF/KLF1 and TAL1/SCL Sustaining the Erythropoiesis

Autophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43

TDP-43 Regulates Coupled Dendritic mRNA Transport-Translation Processes in Co-operation with FMRP and Staufen1

The Mammalian de Novo DNA Methyltransferases DNMT3A and DNMT3B Are Also DNA 5-Hydroxymethylcytosine Dehydroxymethylases

Co-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRP

Phosphorylation-dependent SUMOylation of the transcription factor NF-E2

DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

Structural insights into TDP-43 in nucleic-acid binding and domain interactions

Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease

A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568

Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U

Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage

Therapeutic effect of berberine on TDP-43-related pathogenesis in FTLD and ALS

A robust TDP-43 knock-in mouse model of ALS

Potent and orally active purine-based fetal hemoglobin inducers for treating β-thalassemia and sickle cell disease

Autophagy activation ameliorates neuronal pathogenesis of FTLD-U mice: A new light for treatment of TARDBP/TDP-43 proteinopathies

G-CSF rescues the memory impairment of animal models of Alzheimer's disease

Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells

Negative Regulation of the Differentiation of Flk2 - CD34 - LSK Hematopoietic Stem Cells by EKLF/KLF1

TDP-43 regulates the mammalian spinogenesis through translational repression of Rac1

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