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Phase I and Pharmacokinetic Study of Pemetrexed Administered Every 3 Weeks to Advanced Cancer Patients With Normal and Impaired Renal Function

Journal of clinical oncology, 2006-02, Vol.24 (4), p.552-562

2006

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Current applications of liquid chromatography/mass spectrometry in pharmaceutical discovery after a decade of innovation

Annual review of analytical chemistry (Palo Alto, Calif.), 2008-01, Vol.1 (1), p.357-396

2008

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Detection of Endogenous Malondialdehyde-Deoxyguanosine Adducts in Human Liver

Science (American Association for the Advancement of Science), 1994-09, Vol.265 (5178), p.1580-1582

1994

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Validating regulatory-compliant wide dynamic range bioanalytical assays using chip-based nanoelectrospray tandem mass spectrometry

Rapid communications in mass spectrometry, 2005-01, Vol.19 (1), p.47-56

2005

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Two Drug Interaction Studies Evaluating the Pharmacokinetics and Toxicity of Pemetrexed When Coadministered with Aspirin or Ibuprofen in Patients with Advanced Cancer

Clinical cancer research, 2006-01, Vol.12 (2), p.536-542

2006

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Validation of 96-well Equilibrium Dialysis with Non-radiolabeled Drug for Definitive Measurement of Protein Binding and Application to Clinical Development of Highly-Bound Drugs

Journal of pharmaceutical sciences, 2011-06, Vol.100 (6), p.2498-2507

2011

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Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein

Pharmaceutical research, 1999-03, Vol.16 (3), p.408-414

1999

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Bioanalysis going global

Bioanalysis, 2009-06, Vol.1 (3), p.503-505

Chaudhary, Ajai K

2009

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A review of nanoelectrospray ionization applications for drug metabolism and pharmacokinetics

Current drug metabolism, 2006-12, Vol.7 (8), p.913-928

2006

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Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies

Bioanalysis, 2011-07, Vol.3 (14), p.1635-1646

2011

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Persistence of N7-(2,3,4-Trihydroxybutyl)guanine Adducts in the Livers of Mice and Rats Exposed to 1,3-Butadiene

Chemical research in toxicology, 1999-03, Vol.12 (3), p.247-257

1999

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Cellular Retinoic Acid-Binding Protein(II) Presence in Rat Uterine Epithelial Cells Correlates with Their Synthesis of Retinoic Acid

Biochemistry (Easton), 1997-04, Vol.36 (13), p.4009-4014

1997

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Temperature-Dependent Formation of a Conjugate between Tris(hydroxymethyl)aminomethane Buffer and the Malondialdehyde−DNA Adduct Pyrimidopurinone

Chemical research in toxicology, 1997-05, Vol.10 (5), p.556-561

1997

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Characterization of endogenous DNA adducts by liquid chromatography/electrospray ionization tandem mass spectrometry

Journal of mass spectrometry., 1995-08, Vol.30 (8), p.1157-1166

1995

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Liquid chromatography/electrospray ionization tandem mass spectroscopy (LC/ESI MS/MS) analysis of 1,2-epoxybutene adducts of purine deoxynucleosides

Toxicology (Amsterdam), 1996-10, Vol.113 (1), p.331-335

1996

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Analysis of the malondialdehyde-2′-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry

Biological Mass Spectrometry, 1994-08, Vol.23 (8), p.457-464

1994

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Analysis of the Malondialdehyde−2‘- Deoxyguanosine Adduct Pyrimidopurinone in Human Leukocyte DNA by Gas Chromatography/Electron Capture/Negative Chemical Ionization/Mass Spectrometry

Chemical research in toxicology, 1997-02, Vol.10 (2), p.181-188

1997

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Increased oxygen free radical activity in patients on cardiopulmonary bypass undergoing aortocoronary bypass surgery

The American heart journal, 1992-01, Vol.123 (1), p.37-45

1992

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Quantitative analysis of cimetidine in human plasma using LC/APCI/SRM/MS

Biomedical chromatography, 1999-11, Vol.13 (7), p.455-461

1999

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Characterization of an N6-oxopropenyl-′-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospry ionization tandem mass spectrometry

Carcinogenesis (New York), 1996-05, Vol.17 (5), p.1167-1170

1996

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Oxygen-derived free radicals producing activity and survival of activated polymorphonuclear leukocytes

Molecular and cellular biochemistry, 1991-04, Vol.103 (1), p.51-62

1991

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Characterization of an N 6 -oxopropenyl-′-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospry ionization tandem mass spectrometry

Carcinogenesis (New York), 1996, Vol.17 (5), p.1167-1170

1996

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Oxygen free radical producing activity of polymorphonuclear leukocytes in patients with Parkinson's disease

Molecular and cellular biochemistry, 1992-06, Vol.112 (2), p.181-186

1992

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Role of oxygen free radicals and pH on the release of cardiac lysosomal enzymes

Journal of molecular and cellular cardiology, 1989-11, Vol.21 (11), p.1125-1136

1989

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Effect of oxygen free radicals, hypoxia and pH on the release of liver lysosomal enzymes

Molecular and cellular biochemistry, 1990-04, Vol.94 (1), p.1-8

1990

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Phase I and Pharmacokinetic Study of Pemetrexed Administered Every 3 Weeks to Advanced Cancer Patients With Normal and Impaired Renal Function

Current applications of liquid chromatography/mass spectrometry in pharmaceutical discovery after a decade of innovation

Detection of Endogenous Malondialdehyde-Deoxyguanosine Adducts in Human Liver

Validating regulatory-compliant wide dynamic range bioanalytical assays using chip-based nanoelectrospray tandem mass spectrometry

Two Drug Interaction Studies Evaluating the Pharmacokinetics and Toxicity of Pemetrexed When Coadministered with Aspirin or Ibuprofen in Patients with Advanced Cancer

Validation of 96-well Equilibrium Dialysis with Non-radiolabeled Drug for Definitive Measurement of Protein Binding and Application to Clinical Development of Highly-Bound Drugs

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein

Bioanalysis going global

A review of nanoelectrospray ionization applications for drug metabolism and pharmacokinetics

Dried blood spot sampling: coupling bioanalytical feasibility, blood-plasma partitioning and transferability to in vivo preclinical studies

Persistence of N7-(2,3,4-Trihydroxybutyl)guanine Adducts in the Livers of Mice and Rats Exposed to 1,3-Butadiene

Cellular Retinoic Acid-Binding Protein(II) Presence in Rat Uterine Epithelial Cells Correlates with Their Synthesis of Retinoic Acid

Temperature-Dependent Formation of a Conjugate between Tris(hydroxymethyl)aminomethane Buffer and the Malondialdehyde−DNA Adduct Pyrimidopurinone

Characterization of endogenous DNA adducts by liquid chromatography/electrospray ionization tandem mass spectrometry

Liquid chromatography/electrospray ionization tandem mass spectroscopy (LC/ESI MS/MS) analysis of 1,2-epoxybutene adducts of purine deoxynucleosides

Analysis of the malondialdehyde-2′-deoxyguanosine adduct in rat liver DNA by gas chromatography/electron capture negative chemical ionization mass spectrometry

Analysis of the Malondialdehyde−2‘- Deoxyguanosine Adduct Pyrimidopurinone in Human Leukocyte DNA by Gas Chromatography/Electron Capture/Negative Chemical Ionization/Mass Spectrometry

Increased oxygen free radical activity in patients on cardiopulmonary bypass undergoing aortocoronary bypass surgery

Quantitative analysis of cimetidine in human plasma using LC/APCI/SRM/MS

Characterization of an N6-oxopropenyl-′-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospry ionization tandem mass spectrometry

Oxygen-derived free radicals producing activity and survival of activated polymorphonuclear leukocytes

Characterization of an N 6 -oxopropenyl-′-deoxyadenosine adduct in malondialdehyde-modified DNA using liquid chromatography/electrospry ionization tandem mass spectrometry

Oxygen free radical producing activity of polymorphonuclear leukocytes in patients with Parkinson's disease

Role of oxygen free radicals and pH on the release of cardiac lysosomal enzymes

Effect of oxygen free radicals, hypoxia and pH on the release of liver lysosomal enzymes

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