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Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.7923-7940

2019

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Efficient Regeneration of Graphite from Spent Lithium-Ion Batteries through Combination of Thermal and Wet Metallurgical Approaches

Materials, 2024-08, Vol.17 (16), p.3883

2024

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Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor

Neoplasia (New York, N.Y.), 2020-09, Vol.22 (9), p.431-440

2020

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Deep pore grafting modification for PVDF membrane by supercritical carbon dioxide in combination with ultraviolet irradiation to improve permselectivity and oil/water separation performance

The Journal of supercritical fluids, 2024-01, Vol.204, p.106111, Article 106111

2024

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BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers

Molecular cancer therapeutics, 2015-10, Vol.14 (10), p.2187-2197

2015

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RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K‐RAS mutant tumors

Molecular oncology, 2020-08, Vol.14 (8), p.1833-1849

2020

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Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice

Diabetes (New York, N.Y.), 2008-08, Vol.57 (8), p.2211-2219

2008

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A promising selective recovery process of valuable metals from spent lithium ion batteries via reduction roasting and ammonia leaching

Journal of hazardous materials, 2021-01, Vol.402, p.123491, Article 123491

2021

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Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.1298-1301

2010

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3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists

Bioorganic & medicinal chemistry letters, 2011-06, Vol.21 (11), p.3390-3394

2011

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Discovery of benzimidazole pyrrolidinyl amides as prolylcarboxypeptidase inhibitors

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (5), p.1299-1305

2011

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Discovery of 3-Piperidinyl-1-cyclopentanecarboxamide as a Novel Scaffold for Highly Potent CC Chemokine Receptor 2 Antagonists

Journal of medicinal chemistry, 2007-05, Vol.50 (11), p.2609-2611

2007

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Simulated adsorption of iodine by an amino-metal-organic framework modified with covalent bonds

Environmental science and pollution research international, 2022-12, Vol.29 (59), p.88882-88893

2022

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Design, synthesis, and structure–activity relationship of novel CCR2 antagonists

Bioorganic & medicinal chemistry letters, 2009-03, Vol.19 (6), p.1830-1834

2009

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Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development

Journal of medicinal chemistry, 2020-12, Vol.63 (24), p.15541-15563

2020

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Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

Clinical cancer research, 2020-10, Vol.26 (19), p.5232-5245

2020

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Synergistic leaching mechanism of chloride ions for extracting manganese completely from manganese carbonate ores

Journal of environmental chemical engineering, 2021-02, Vol.9 (1), p.104918, Article 104918

2021

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Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists

Bioorganic & medicinal chemistry letters, 2006-07, Vol.16 (14), p.3735-3739

2006

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Blockade of HMGB1 preserves vascular homeostasis and improves blood perfusion in rats of acute limb ischemia/reperfusion

Microvascular research, 2017-07, Vol.112, p.37-40

2017

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Solid-Phase Unnatural Peptide Synthesis (UPS)

Journal of the American Chemical Society, 1996-06, Vol.118 (25), p.6070-6071

1996

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Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl‑2

Journal of medicinal chemistry, 2024-05, Vol.67 (10), p.7836-7858

2024

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Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B‑Cell Malignancies and Autoimmune Diseases

Journal of medicinal chemistry, 2023-03, Vol.66 (6), p.4025-4044

2023

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α-Aminothiazole-γ-aminobutanoic amides as potent, small molecule CCR2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2007-01, Vol.17 (2), p.309-314

2007

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Abstract 6415: RAF dimer inhibitor lifirafenib enhances the antitumor activity of MEK inhibitor mirdametinib in RAS mutant tumors

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6415-6415

2020

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The Enantioselective Synthesis of α-Amino Acid Derivatives via Organoboranes

Journal of the American Chemical Society, 2002-08, Vol.124 (32), p.9348-9349

2002

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Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase

Efficient Regeneration of Graphite from Spent Lithium-Ion Batteries through Combination of Thermal and Wet Metallurgical Approaches

Pamiparib is a potent and selective PARP inhibitor with unique potential for the treatment of brain tumor

Deep pore grafting modification for PVDF membrane by supercritical carbon dioxide in combination with ultraviolet irradiation to improve permselectivity and oil/water separation performance

BGB-283, a Novel RAF Kinase and EGFR Inhibitor, Displays Potent Antitumor Activity in BRAF-Mutated Colorectal Cancers

RAF dimer inhibition enhances the antitumor activity of MEK inhibitors in K‐RAS mutant tumors

Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice

A promising selective recovery process of valuable metals from spent lithium ion batteries via reduction roasting and ammonia leaching

Discovery of 5-aryloxy-2,4-thiazolidinediones as potent GPR40 agonists

3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists

Discovery of benzimidazole pyrrolidinyl amides as prolylcarboxypeptidase inhibitors

Discovery of 3-Piperidinyl-1-cyclopentanecarboxamide as a Novel Scaffold for Highly Potent CC Chemokine Receptor 2 Antagonists

Simulated adsorption of iodine by an amino-metal-organic framework modified with covalent bonds

Design, synthesis, and structure–activity relationship of novel CCR2 antagonists

Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development

Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma

Synergistic leaching mechanism of chloride ions for extracting manganese completely from manganese carbonate ores

Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists

Blockade of HMGB1 preserves vascular homeostasis and improves blood perfusion in rats of acute limb ischemia/reperfusion

Solid-Phase Unnatural Peptide Synthesis (UPS)

Discovery of the Clinical Candidate Sonrotoclax (BGB-11417), a Highly Potent and Selective Inhibitor for Both WT and G101V Mutant Bcl‑2

Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase for B‑Cell Malignancies and Autoimmune Diseases

α-Aminothiazole-γ-aminobutanoic amides as potent, small molecule CCR2 receptor antagonists

Abstract 6415: RAF dimer inhibitor lifirafenib enhances the antitumor activity of MEK inhibitor mirdametinib in RAS mutant tumors

The Enantioselective Synthesis of α-Amino Acid Derivatives via Organoboranes

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