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Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (46), p.E1120-E1127

2011

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AKT/PKB AND OTHER D3 PHOSPHOINOSITIDE-REGULATED KINASES: Kinase Activation by Phosphoinositide-Dependent Phosphorylation

Annual review of biochemistry, 1999-01, Vol.68 (1), p.965-1014

1999

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miR-146a targets Fos expression in human cardiac cells

Disease models & mechanisms, 2015-09, Vol.8 (9), p.1081-1091

2015

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Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response

Biochemical journal, 2015-10, Vol.471 (1), p.37-51

2015

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The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells

PloS one, 2011-05, Vol.6 (5), p.e19724-e19724

2011

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A Truncated Fragment of Src Protein Kinase Generated by Calpain-mediated Cleavage Is a Mediator of Neuronal Death in Excitotoxicity

The Journal of biological chemistry, 2013-04, Vol.288 (14), p.9696-9709

2013

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Akt activation by growth factors is a multiple-step process : the role of the PH domain

Oncogene, 1998-07, Vol.17 (3), p.313-325

1998

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Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

Molecular and Cellular Biology, 1997-08, Vol.17 (8), p.4406-4418

1997

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Transduction of Interleukin-2 Antiapoptotic and Proliferative Signals via Akt Protein Kinase

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (8), p.3627-3632

1997

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Cell, 1995-06, Vol.81 (5), p.727-736

1995

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Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload

PloS one, 2012, Vol.7 (7), p.e39919-e39919

2012

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Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases

Cell cycle (Georgetown, Tex.), 2012-02, Vol.11 (3), p.475-478

2012

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The p65 subunit of NF-κB binds to PGC-1α, linking inflammation and metabolic disturbances in cardiac cells

Cardiovascular research, 2010-08, Vol.87 (3), p.449-458

2010

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A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation

The Journal of biological chemistry, 2020-03, Vol.295 (10), p.3316-3329

2020

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Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage

Cancer research (Chicago, Ill.), 2003-01, Vol.63 (1), p.1-5

2003

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Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration

American journal of physiology. Heart and circulatory physiology, 2009-08, Vol.297 (2), p.H590-H601

2009

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The Gfi-1 Protooncoprotein Represses Bax Expression and Inhibits T-Cell Death

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (25), p.14569-14573

1996

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Regulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange

American journal of physiology. Heart and circulatory physiology, 2011-03, Vol.300 (3), p.H859-H868

2011

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Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density

American journal of physiology. Heart and circulatory physiology, 2011-11, Vol.301 (5), p.H1932-H1940

2011

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Cardioprotection of Controlled and Cardiac-Specific Over-Expression of A2A-Adenosine Receptor in the Pressure Overload

PloS one, 2012-07, Vol.7 (7), p.e39919

2012

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Tumor necrosis factor receptors 1 and 2 differentially regulate survival, cardiac dysfunction, and remodeling in transgenic mice with tumor necrosis factor-α-induced cardiomyopathy

Circulation (New York, N.Y.), 2004-04, Vol.109 (15), p.1892-1897

2004

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Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger

American journal of physiology. Heart and circulatory physiology, 2012-02, Vol.302 (3), p.H770-H781

2012

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Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

Cancer cell, 2002-03, Vol.1 (2), p.181-191

2002

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Induced overexpression of Na(+)/Ca(2+) exchanger does not aggravate myocardial dysfunction induced by transverse aortic constriction

Journal of cardiac failure, 2013-01, Vol.19 (1), p.60-70

2013

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Resistance of Akt kinases to dephosphorylation through ATP-dependent conformational plasticity

AKT/PKB AND OTHER D3 PHOSPHOINOSITIDE-REGULATED KINASES: Kinase Activation by Phosphoinositide-Dependent Phosphorylation

miR-146a targets Fos expression in human cardiac cells

Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response

The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells

A Truncated Fragment of Src Protein Kinase Generated by Calpain-mediated Cleavage Is a Mediator of Neuronal Death in Excitotoxicity

Akt activation by growth factors is a multiple-step process : the role of the PH domain

Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation

Transduction of Interleukin-2 Antiapoptotic and Proliferative Signals via Akt Protein Kinase

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Cardioprotection of controlled and cardiac-specific over-expression of A(2A)-adenosine receptor in the pressure overload

Autoregulation of kinase dephosphorylation by ATP binding in AGC protein kinases

Left Ventricular Dysfunction in Murine Models of Heart Failure and in Failing Human Heart is Associated With a Selective Decrease in the Expression of Caveolin-3

The p65 subunit of NF-κB binds to PGC-1α, linking inflammation and metabolic disturbances in cardiac cells

A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation

Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage

Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration

The Gfi-1 Protooncoprotein Represses Bax Expression and Inhibits T-Cell Death

Regulation of in vivo cardiac contractility by phospholemman: role of Na+/Ca2+ exchange

Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density

Cardioprotection of Controlled and Cardiac-Specific Over-Expression of A2A-Adenosine Receptor in the Pressure Overload

Tumor necrosis factor receptors 1 and 2 differentially regulate survival, cardiac dysfunction, and remodeling in transgenic mice with tumor necrosis factor-α-induced cardiomyopathy

Constitutive overexpression of phosphomimetic phospholemman S68E mutant results in arrhythmias, early mortality, and heart failure: potential involvement of Na+/Ca2+ exchanger

Small GTPases and tyrosine kinases coregulate a molecular switch in the phosphoinositide 3-kinase regulatory subunit

Induced overexpression of Na(+)/Ca(2+) exchanger does not aggravate myocardial dysfunction induced by transverse aortic constriction

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