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Stimulation of Autophagy Improves Endoplasmic Reticulum Stress―Induced Diabetes

Diabetes (New York, N.Y.), 2013-04, Vol.62 (4), p.1227-1237

2013

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Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors

Cell reports (Cambridge), 2020-07, Vol.32 (4), p.107954-107954, Article 107954

2020

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Autophagy is a major regulator of beta cell insulin homeostasis

Diabetologia, 2016-07, Vol.59 (7), p.1480-1491

2016

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Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse

eLife, 2018-11, Vol.7

2018

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mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

Diabetes (New York, N.Y.), 2008-04, Vol.57 (4), p.945-957

2008

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Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1

PloS one, 2009-03, Vol.4 (3), p.e4954-e4954

2009

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AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells

PloS one, 2011-12, Vol.6 (12), p.e28804

2011

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Regulation of GLUT4 activity in myotubes by 3-O-methyl-d-glucose

Biochimica et biophysica acta. Biomembranes, 2017-10, Vol.1859 (10), p.1900-1910

2017

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A Novel Phenylchromane Derivative Increases the Rate of Glucose Uptake in L6 Myotubes and Augments Insulin Secretion from Pancreatic Beta-Cells by Activating AMPK

Pharmaceutical research, 2017-12, Vol.34 (12), p.2873-2890

2017

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Foam cell‐derived 4‐hydroxynonenal induces endothelial cell senescence in a TXNIP‐dependent manner

Journal of cellular and molecular medicine, 2015-08, Vol.19 (8), p.1887-1899

2015

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Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition

JCI insight, 2023-04, Vol.8 (7)

2023

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Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

Data in brief, 2017-10, Vol.14 (C), p.329-336

2017

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Regulation of pdx-1 Gene Expression

Diabetes (New York, N.Y.), 2002-12, Vol.51 (suppl 3), p.S320-S325

2002

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Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Diabetes (New York, N.Y.), 2005-12, Vol.54 (suppl 2), p.S137-S144

2005

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Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment

Diabetes care, 1997-09, Vol.20 (9), p.1353

1997

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β-Cell Protein Kinases and the Dynamics of the Insulin Response to Glucose

Diabetes (New York, N.Y.), 2002-02, Vol.51 (suppl 1), p.S68-S73

2002

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Effects of proinsulin misfolding on β‐cell dynamics, differentiation and function in diabetes

Diabetes, obesity & metabolism, 2018-09, Vol.20 (S2), p.95-103

2018

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Purification of the β -cell Glucose-Sensitive Factor that Transactivates the Insulin Gene Differentially in Normal and Transformed Islet Cells

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (26), p.15057-15062

1996

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Modeling phasic insulin release: Immediate and time-dependent effects of glucose

Diabetes (New York, N.Y.), 2002-02, Vol.51 (2), p.S53-S59

2002

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Autophagy is a major regulator of beta cell insulin homeostasis

Diabetologia, 2016-07, Vol.59 (7), p.1480-1491

2016

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Opposing effects of intracellular versus extracellular adenine nucleotides on autophagy: implications for β-cell function

Journal of cell science, 2018-08, Vol.131 (15)

2018

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IPF1/PDX1 Deficiency and β-Cell Dysfunction in Psammomys obesus, an Animal With Type 2 Diabetes

Diabetes (New York, N.Y.), 2001-08, Vol.50 (8), p.1799-1806

2001

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AMPK Regulates ER Morphology and Function in Stressed Pancreatic β-Cells via Phosphorylation of DRP1

Molecular endocrinology (Baltimore, Md.), 2013-10, Vol.27 (10), p.1706-1723

2013

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Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production

Diabetologia, 2023-10, Vol.66 (10), p.1925-1942

2023

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Synthesis and Mechanism of Hypoglycemic Activity of Benzothiazole Derivatives

Journal of medicinal chemistry, 2013-07, Vol.56 (13), p.5335-5350

2013

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Stimulation of Autophagy Improves Endoplasmic Reticulum Stress―Induced Diabetes

Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors

Autophagy is a major regulator of beta cell insulin homeostasis

Inhibition of mTORC1 by ER stress impairs neonatal β-cell expansion and predisposes to diabetes in the Akita mouse

mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes

Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1

AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells

Regulation of GLUT4 activity in myotubes by 3-O-methyl-d-glucose

A Novel Phenylchromane Derivative Increases the Rate of Glucose Uptake in L6 Myotubes and Augments Insulin Secretion from Pancreatic Beta-Cells by Activating AMPK

Foam cell‐derived 4‐hydroxynonenal induces endothelial cell senescence in a TXNIP‐dependent manner

Mapping the metabolic reprogramming induced by sodium-glucose cotransporter 2 inhibition

Supportive data on the regulation of GLUT4 activity by 3-O-methyl-D-glucose

Regulation of pdx-1 Gene Expression

Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment

β-Cell Protein Kinases and the Dynamics of the Insulin Response to Glucose

Effects of proinsulin misfolding on β‐cell dynamics, differentiation and function in diabetes

Purification of the β -cell Glucose-Sensitive Factor that Transactivates the Insulin Gene Differentially in Normal and Transformed Islet Cells

Modeling phasic insulin release: Immediate and time-dependent effects of glucose

Autophagy is a major regulator of beta cell insulin homeostasis

Opposing effects of intracellular versus extracellular adenine nucleotides on autophagy: implications for β-cell function

IPF1/PDX1 Deficiency and β-Cell Dysfunction in Psammomys obesus, an Animal With Type 2 Diabetes

AMPK Regulates ER Morphology and Function in Stressed Pancreatic β-Cells via Phosphorylation of DRP1

Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production

Synthesis and Mechanism of Hypoglycemic Activity of Benzothiazole Derivatives

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