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Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance

Current cancer drug targets, 2012-03, Vol.12 (3), p.197-209

2012

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EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

Oncogene, 2014-05, Vol.33 (19), p.2504-2512

2014

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EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway

Oncogene, 2012-09, Vol.31 (36), p.4054-4066

2012

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Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

Cancer research (Chicago, Ill.), 2000-02, Vol.60 (4), p.847-853

2000

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IGFBP2 potentiates nuclear EGFR–STAT3 signaling

Oncogene, 2016-02, Vol.35 (6), p.738-747

2016

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A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments

Carcinogenesis (New York), 2013-04, Vol.34 (4), p.725-738

2013

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EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway

Oncogene, 2012-09, Vol.31 (36), p.4054

2012

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Methylation-associated silencing of the tissue inhibitor of Metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers

Cancer research (Chicago, Ill.), 1999-02, Vol.59 (4), p.798-802

1999

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A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

Cancer research (Chicago, Ill.), 1996-11, Vol.56 (21), p.5079-5086

1996

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D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability

Cancer research (Chicago, Ill.), 1999-05, Vol.59 (10), p.2297-2301

1999

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The potential of TRAIL for cancer chemotherapy

Apoptosis (London), 2001-06, Vol.6 (3), p.191

2001

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Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily

Genomics (San Diego, Calif.), 1998-01, Vol.47 (2), p.187-199

1998

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Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase

Cancer research (Chicago, Ill.), 1999-04, Vol.59 (7), p.1464-1472

1999

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Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

Oncogene, 2015-07, Vol.34 (31), p.4078-4088

2015

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Disruption of Forkhead Transcription Factor (FOXO) Family Members in Mice Reveals Their Functional Diversification

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.2975-2980

2004

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A Global Transcriptional Regulatory Role for c-Myc in Burkitt's Lymphoma Cells

Proceedings of the National Academy of Sciences - PNAS, 2003-07, Vol.100 (14), p.8164-8169

2003

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A Mutant Epidermal Growth Factor Receptor Common in Human Glioma Confers Enhanced Tumorigenicity

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (16), p.7727-7731

1994

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The WHO Classification of Tumors of the Nervous System

Journal of neuropathology and experimental neurology, 2002-03, Vol.61 (3), p.215-225

2002

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Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation

Cancer research (Chicago, Ill.), 1996-05, Vol.56 (10), p.2405-2410

1996

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PTEN gene transfer in human malignant glioma : sensitization to irradiation and CD95L-induced apoptosis

Oncogene, 1999-07, Vol.18 (27), p.3936-3943

1999

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Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

Nature genetics, 2002-10, Vol.32 (2), p.245-253

2002

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Suppression of Glioblastoma Angiogenicity and Tumorigenicity by Inhibition of Endogenous Expression of Vascular Endothelial Growth Factor

Proceedings of the National Academy of Sciences - PNAS, 1996-08, Vol.93 (16), p.8502-8507

1996

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Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor

Journal of neurosurgery, 2001-09, Vol.95 (3), p.472-479

2001

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Protein Kinase B/Akt-Mediated Phosphorylation Promotes Nuclear Exclusion of the Winged Helix Transcription Factor FKHR1

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (13), p.7421-7426

1999

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The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

Cancer research (Chicago, Ill.), 1998-11, Vol.58 (22), p.5002-5008

1998

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Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180

EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo

IGFBP2 potentiates nuclear EGFR–STAT3 signaling

A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments

EGFRvIII promotes glioma angiogenesis and growth through the NF-[kappa]B, interleukin-8 pathway

Methylation-associated silencing of the tissue inhibitor of Metalloproteinase-3 gene suggests a suppressor role in kidney, brain, and other human cancers

A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis

D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability

The potential of TRAIL for cancer chemotherapy

Cloning and Characterization of Three Human Forkhead Genes That Comprise an FKHR-like Gene Subfamily

Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase

Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling

Disruption of Forkhead Transcription Factor (FOXO) Family Members in Mice Reveals Their Functional Diversification

A Global Transcriptional Regulatory Role for c-Myc in Burkitt's Lymphoma Cells

A Mutant Epidermal Growth Factor Receptor Common in Human Glioma Confers Enhanced Tumorigenicity

The WHO Classification of Tumors of the Nervous System

Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation

PTEN gene transfer in human malignant glioma : sensitization to irradiation and CD95L-induced apoptosis

Regulation of insulin action and pancreatic β-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1

Suppression of Glioblastoma Angiogenicity and Tumorigenicity by Inhibition of Endogenous Expression of Vascular Endothelial Growth Factor

Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor

Protein Kinase B/Akt-Mediated Phosphorylation Promotes Nuclear Exclusion of the Winged Helix Transcription Factor FKHR1

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

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