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Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

The Lancet (British edition), 2014-05, Vol.383 (9932), p.1899-1911

2014

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Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

The Lancet (British edition), 2015-06, Vol.385 (9984), p.2264-2271

2015

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Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

The Lancet (British edition), 2015-11, Vol.386 (10008), p.2059-2068

2015

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Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

Nature (London), 2022-11, Vol.611 (7934), p.105-114

2022

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The 100 000 Genomes Project: bringing whole genome sequencing to the NHS

BMJ (Online), 2018-04, Vol.361, p.k1687

2018

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Advances in Blood Pressure Genomics

Circulation research, 2013-05, Vol.112 (10), p.1365-1379

2013

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ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon

Nature communications, 2023-10, Vol.14 (1), p.6156-6156, Article 6156

2023

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Endothelial C-type natriuretic peptide maintains vascular homeostasis

The Journal of clinical investigation, 2014-09, Vol.124 (9), p.4039-4051

2014

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Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

American journal of human genetics, 2008-01, Vol.82 (1), p.139-149

2008

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Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations

American journal of medical genetics. Part A, 2022-03, Vol.188 (3), p.959-964

2022

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Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction

PLoS genetics, 2016-07, Vol.12 (7), p.e1006127-e1006127

2016

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Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

The lancet. Diabetes & endocrinology, 2016-02, Vol.4 (2), p.136-147

2016

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ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant

American journal of human genetics, 2013-03, Vol.92 (3), p.366-374

2013

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Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients: A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study

Hypertension (Dallas, Tex. 1979), 2015-02, Vol.65 (2), p.320-327

2015

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Factor V Leiden, estrogen, and multimorbidity association with venous thromboembolism in a British-South Asian cohort

iScience, 2023-10, Vol.26 (10), p.107795-107795, Article 107795

2023

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Personalized Antihypertensive Treatment Optimization With Smartphone-Enabled Remote Precision Dosing of Amlodipine During the COVID-19 Pandemic (PERSONAL-CovidBP Trial)

Journal of the American Heart Association, 2024-02, Vol.13 (4), p.e030749-e030749

2024

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Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank

Journal of public health (Oxford, England), 2020-08, Vol.42 (3), p.451-460

2020

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Genes for blood pressure: an opportunity to understand hypertension

European heart journal, 2013-04, Vol.34 (13), p.951-961

2013

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White Blood Cells and Blood Pressure: A Mendelian Randomization Study

Circulation (New York, N.Y.), 2020-04, Vol.141 (16), p.1307-1317

2020

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The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

Frontiers in pharmacology, 2022-01, Vol.12, p.679857-679857

2022

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Equal access to pharmacogenomics testing: The ethical imperative for population‐wide access in the UK NHS

British journal of clinical pharmacology, 2023-05, Vol.89 (5), p.1701-1703

2023

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Use of Genomics to Develop Novel Therapeutics and Personalize Hypertension Therapy

Arteriosclerosis, thrombosis, and vascular biology, 2024-04, Vol.44 (4), p.784-793

2024

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Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

Circulation (New York, N.Y.), 2017-06, Vol.135 (24), p.2373-2388

2017

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Impact of amlodipine-based therapy among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial−Blood Pressure Lowering Arm (ASCOT-BPLA)

Journal of hypertension, 2011-03, Vol.29 (3), p.583-591

2011

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Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

European heart journal, 2023-06, Vol.44 (23), p.2114-2125

2023

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Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people

Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials

Spironolactone versus placebo, bisoprolol, and doxazosin to determine the optimal treatment for drug-resistant hypertension (PATHWAY-2): a randomised, double-blind, crossover trial

Nuclear-embedded mitochondrial DNA sequences in 66,083 human genomes

The 100 000 Genomes Project: bringing whole genome sequencing to the NHS

Advances in Blood Pressure Genomics

ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon

Endothelial C-type natriuretic peptide maintains vascular homeostasis

Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia

Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations

Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction

Effect of amiloride, or amiloride plus hydrochlorothiazide, versus hydrochlorothiazide on glucose tolerance and blood pressure (PATHWAY-3): a parallel-group, double-blind randomised phase 4 trial

ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant

Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients: A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study

Factor V Leiden, estrogen, and multimorbidity association with venous thromboembolism in a British-South Asian cohort

Personalized Antihypertensive Treatment Optimization With Smartphone-Enabled Remote Precision Dosing of Amlodipine During the COVID-19 Pandemic (PERSONAL-CovidBP Trial)

Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank

Genes for blood pressure: an opportunity to understand hypertension

White Blood Cells and Blood Pressure: A Mendelian Randomization Study

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

Equal access to pharmacogenomics testing: The ethical imperative for population‐wide access in the UK NHS

Use of Genomics to Develop Novel Therapeutics and Personalize Hypertension Therapy

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis

Impact of amlodipine-based therapy among older and younger patients in the Anglo-Scandinavian Cardiac Outcomes Trial−Blood Pressure Lowering Arm (ASCOT-BPLA)

Genetic analyses identify brain structures related to cognitive impairment associated with elevated blood pressure

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