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Hepatic drug transporters and nuclear receptors: regulation by therapeutic agents

World journal of gastroenterology : WJG, 2008-12, Vol.14 (46), p.7068-7074

2008

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Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole

Memórias do Instituto Oswaldo Cruz, 2016-11, Vol.111 (11), p.707-711

2016

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Modulation of Biotransformation Systems and ABC Transporters by Benznidazole in Rats

Antimicrobial Agents and Chemotherapy, 2013-10, Vol.57 (10), p.4894-4902

2013

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Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor

PLoS neglected tropical diseases, 2012-12, Vol.6 (12), p.e1951

2012

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Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2

Drug metabolism and disposition, 2007-11, Vol.35 (11), p.2060-2066

2007

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Induction of P-glycoprotein expression and activity by prolactin in female rat liver

Life sciences (1973), 2021-12, Vol.287, p.119936, Article 119936

2021

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Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis

Toxicology and applied pharmacology, 2017-01, Vol.315, p.12-22

2017

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Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats

Drug metabolism and disposition, 2008-03, Vol.36 (3), p.475-480

2008

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Shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats

The Journal of pharmacology and experimental therapeutics, 2005-12, Vol.315 (3), p.987-995

2005

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Regulation of expression and activity of rat intestinal multidrug resistance-associated protein 2 by cholestatic estrogens

Drug metabolism and disposition, 2009-06, Vol.37 (6), p.1277-1285

2009

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Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity

Toxicology (Amsterdam), 2014-06, Vol.320, p.46-55

2014

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Induction of rat intestinal P-glycoprotein by spironolactone and its effect on absorption of orally administered digoxin

The Journal of pharmacology and experimental therapeutics, 2006-09, Vol.318 (3), p.1146-1152

2006

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Ethynylestradiol increases expression and activity of rat liver MRP3

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.1030-1034

2006

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Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein

Biochemical pharmacology, 2004-08, Vol.68 (4), p.791-798

2004

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Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor

Drug metabolism and disposition, 2013-02, Vol.41 (2), p.275-280

2013

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Galactosamine prevents ethinylestradiol-induced cholestasis

Drug metabolism and disposition, 2006-06, Vol.34 (6), p.993-997

2006

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Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats

Drug metabolism and disposition, 2006-08, Vol.34 (8), p.1301-1309

2006

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Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis

The Journal of pharmacology and experimental therapeutics, 2003-07, Vol.306 (1), p.279-286

2003

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Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat

Drug metabolism and disposition, 2005-07, Vol.33 (7), p.888-891

2005

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Co-regulation of expression of phase II metabolizing enzymes and multidrug resistance-associated protein 2

Annals of hepatology, 2004-01, Vol.3 (1), p.11-17

2004

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Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose

Biochemical pharmacology, 2009-05, Vol.77 (10), p.1621-1628

2009

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Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat

The Journal of pharmacology and experimental therapeutics, 2010-11, Vol.335 (2), p.332-341

2010

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Effect of spironolactone on the expression of rat hepatic UDP-glucuronosyltransferase

Biochemical pharmacology, 2003-07, Vol.66 (1), p.171-177

2003

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Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene

Drug metabolism and disposition, 2012-07, Vol.40 (7), p.1252-1258

2012

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Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats

European journal of pharmacology, 2009-11, Vol.623 (1), p.103-106

2009

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Hepatic drug transporters and nuclear receptors: regulation by therapeutic agents

Up-regulation of ATP-binding cassette transporters in the THP-1 human macrophage cell line by the antichagasic benznidazole

Modulation of Biotransformation Systems and ABC Transporters by Benznidazole in Rats

Regulation of biotransformation systems and ABC transporters by benznidazole in HepG2 cells: involvement of pregnane X-receptor

Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2

Induction of P-glycoprotein expression and activity by prolactin in female rat liver

Benznidazole, the trypanocidal drug used for Chagas disease, induces hepatic NRF2 activation and attenuates the inflammatory response in a murine model of sepsis

Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats

Shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats

Regulation of expression and activity of rat intestinal multidrug resistance-associated protein 2 by cholestatic estrogens

Regulation of expression and activity of multidrug resistance proteins MRP2 and MDR1 by estrogenic compounds in Caco-2 cells. Role in prevention of xenobiotic-induced cytotoxicity

Induction of rat intestinal P-glycoprotein by spironolactone and its effect on absorption of orally administered digoxin

Ethynylestradiol increases expression and activity of rat liver MRP3

Effect of acetaminophen on expression and activity of rat liver multidrug resistance-associated protein 2 and P-glycoprotein

Induction of hepatic multidrug resistance-associated protein 3 by ethynylestradiol is independent of cholestasis and mediated by estrogen receptor

Galactosamine prevents ethinylestradiol-induced cholestasis

Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats

Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis

Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat

Co-regulation of expression of phase II metabolizing enzymes and multidrug resistance-associated protein 2

Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose

Induction of intestinal multidrug resistance-associated protein 2 by glucagon-like Peptide 2 in the rat

Effect of spironolactone on the expression of rat hepatic UDP-glucuronosyltransferase

Effect of glucagon-like peptide 2 on hepatic, renal, and intestinal disposition of 1-chloro-2,4-dinitrobenzene

Induction of intestinal multidrug resistance-associated protein 2 (Mrp2) by spironolactone in rats

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