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Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells

American Journal of Physiology: Cell Physiology, 2009-05, Vol.296 (5), p.C1162-C1170

2009

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Nuclear Countermeasure Activity of TP508 Linked to Restoration of Endothelial Function and Acceleration of DNA Repair

Radiation research, 2016-08, Vol.186 (2), p.162

2016

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Controlled release of an osteogenic peptide from injectable biodegradable polymeric composites

Journal of controlled release, 2002-12, Vol.84 (3), p.137-150

2002

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Thrombin peptide (TP508) promotes fracture repair by up-regulating inflammatory mediators, early growth factors, and increasing angiogenesis

Journal of orthopaedic research, 2005-05, Vol.23 (3), p.671-679

2005

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Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis

Journal of orthopaedic research, 2005, Vol.23 (1), p.196-202

2005

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Effect of varied release kinetics of the osteogenic thrombin peptide TP508 from biodegradable, polymeric scaffolds on bone formation in vivo

Journal of biomedical materials research. Part A, 2005-03, Vol.72A (4), p.343-353

2005

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Radiomitigation and Tissue Repair Activity of Systemically Administered Therapeutic Peptide TP508 Is Enhanced by PEGylation

The AAPS journal, 2017-05, Vol.19 (3), p.743-753

2017

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Thrombin Peptide TP508 Stimulates Rapid Nitric Oxide Production in Human Endothelial Cells

Journal of vascular research, 2010-01, Vol.47 (3), p.203-213

2010

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Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity

Laboratory investigation, 2015-11, Vol.95 (11), p.1222-1233

2015

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Thrombin peptide Chrysalin® stimulates healing of diabetic foot ulcers in a placebo-controlled phase I/II study

Wound repair and regeneration, 2007-01, Vol.15 (1), p.23-34

2007

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Systemic Administration of Thrombin Peptide TP508 Enhances VEGF-Stimulated Angiogenesis and Attenuates Effects of Chronic Hypoxia

Journal of vascular research, 2013-01, Vol.50 (3), p.186-196

2013

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In vivo degradation of porous poly(propylene fumarate)/poly( DL-lactic- co-glycolic acid) composite scaffolds

Biomaterials, 2005-08, Vol.26 (22), p.4616-4623

2005

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Acceleration of full-thickness wound healing in normal rats by the synthetic thrombin peptide, TP508

Wound repair and regeneration, 2000-05, Vol.8 (3), p.204-215

2000

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A comprehensive preclinical assessment of late-term imaging markers of radiation-induced brain injury

Neuro-oncology advances, 2019-05, Vol.1 (1), p.vdz012

2019

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Could rusalatide acetate be the future drug of choice for diabetic foot ulcers and fracture repair?

Expert opinion on pharmacotherapy, 2008-10, Vol.9 (15), p.2717-2726

2008

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In vitro release of plasmid DNA from oligo(poly(ethylene glycol) fumarate) hydrogels

Journal of controlled release, 2005-06, Vol.104 (3), p.521-539

2005

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Thrombin peptide TP508 stimulates cellular events leading to angiogenesis, revascularization, and repair of dermal and musculoskeletal tissues

Journal of bone and joint surgery. American volume, 2006-11, Vol.88 Suppl 3, p.132

2006

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Repair of rabbit segmental defects with the thrombin peptide, TP508

Journal of orthopaedic research, 2004-09, Vol.22 (5), p.1094-1099

2004

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Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia

Wound repair and regeneration, 2000-11, Vol.8 (6), p.517-529

2000

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Inhibition of Phosphate-Induced Apoptosis in Resting Zone Chondrocytes by Thrombin Peptide 508

Cells, tissues, organs, 2009-01, Vol.189 (1-4), p.56-59

2009

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THROMBIN ENHANCEMENT OF INTERLEUKIN-1 EXPRESSION IN MONONUCLEAR CELLS: INVOLVEMENT OF PROTEINASE-ACTIVATED RECEPTOR-1

Cytokine (Philadelphia, Pa.), 2002-12, Vol.20 (5), p.191-199

2002

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Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation

Journal of cellular physiology, 1998-10, Vol.177 (1), p.76-84

1998

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Abstract 3341: TP508 sensitizes cancer stem cells to radiation and delays brain cancer cell relapse in vitro

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.3341-3341

2015

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TP508 (Chrysalin®) Reverses Endothelial Dysfunction and Increases Perfusion and Myocardial Function in Hearts With Chronic Ischemia

Journal of cardiovascular pharmacology and therapeutics, 2008-09, Vol.13 (3), p.214-225

2008

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The thrombin peptide, TP508, enhances cytokine release and activates signaling events

Peptides (New York, N.Y. : 1980), 2004-11, Vol.25 (11), p.1917-1926

2004

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Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells

Nuclear Countermeasure Activity of TP508 Linked to Restoration of Endothelial Function and Acceleration of DNA Repair

Controlled release of an osteogenic peptide from injectable biodegradable polymeric composites

Thrombin peptide (TP508) promotes fracture repair by up-regulating inflammatory mediators, early growth factors, and increasing angiogenesis

Bone formation is enhanced by thrombin-related peptide TP508 during distraction osteogenesis

Effect of varied release kinetics of the osteogenic thrombin peptide TP508 from biodegradable, polymeric scaffolds on bone formation in vivo

Radiomitigation and Tissue Repair Activity of Systemically Administered Therapeutic Peptide TP508 Is Enhanced by PEGylation

Thrombin Peptide TP508 Stimulates Rapid Nitric Oxide Production in Human Endothelial Cells

Novel regenerative peptide TP508 mitigates radiation-induced gastrointestinal damage by activating stem cells and preserving crypt integrity

Thrombin peptide Chrysalin® stimulates healing of diabetic foot ulcers in a placebo-controlled phase I/II study

Systemic Administration of Thrombin Peptide TP508 Enhances VEGF-Stimulated Angiogenesis and Attenuates Effects of Chronic Hypoxia

In vivo degradation of porous poly(propylene fumarate)/poly( DL-lactic- co-glycolic acid) composite scaffolds

Acceleration of full-thickness wound healing in normal rats by the synthetic thrombin peptide, TP508

A comprehensive preclinical assessment of late-term imaging markers of radiation-induced brain injury

Could rusalatide acetate be the future drug of choice for diabetic foot ulcers and fracture repair?

In vitro release of plasmid DNA from oligo(poly(ethylene glycol) fumarate) hydrogels

Thrombin peptide TP508 stimulates cellular events leading to angiogenesis, revascularization, and repair of dermal and musculoskeletal tissues

Repair of rabbit segmental defects with the thrombin peptide, TP508

Thrombin peptide TP508 accelerates closure of dermal excisions in animal tissue with surgically induced ischemia

Inhibition of Phosphate-Induced Apoptosis in Resting Zone Chondrocytes by Thrombin Peptide 508

THROMBIN ENHANCEMENT OF INTERLEUKIN-1 EXPRESSION IN MONONUCLEAR CELLS: INVOLVEMENT OF PROTEINASE-ACTIVATED RECEPTOR-1

Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation

Abstract 3341: TP508 sensitizes cancer stem cells to radiation and delays brain cancer cell relapse in vitro

TP508 (Chrysalin®) Reverses Endothelial Dysfunction and Increases Perfusion and Myocardial Function in Hearts With Chronic Ischemia

The thrombin peptide, TP508, enhances cytokine release and activates signaling events

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