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Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.329-344

2011

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The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products

Pharmacology & therapeutics (Oxford), 2008-10, Vol.120 (1), p.71-80

2008

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Effect of Plasma Protein Binding on in Vivo Activity and Brain Penetration of Glycine/NMDA Receptor Antagonists

Journal of medicinal chemistry, 1997-12, Vol.40 (25), p.4053-4068

1997

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4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor

Journal of medicinal chemistry, 1992-05, Vol.35 (11), p.1954-1968

1992

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4-Substituted-3-phenylquinolin-2(1H)-ones: Acidic and Nonacidic Glycine Site N-Methyl-d-aspartate Antagonists with in Vivo Activity

Journal of medicinal chemistry, 1997-02, Vol.40 (5), p.754-765

1997

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Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

Journal of medicinal chemistry, 1991-04, Vol.34 (4), p.1243-1252

1991

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Characterization of the binding of [3H]L-689,560, an antagonist for the glycine site on the N-methyl-D-aspartate receptor, to rat brain membranes

Molecular pharmacology, 1992-05, Vol.41 (5), p.923-930

1992

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3-Nitro-3,4-dihydro-2(1H)quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors

Journal of medicinal chemistry, 1993-10, Vol.36 (22), p.3397-3408

1993

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2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor

Journal of medicinal chemistry, 1992-05, Vol.35 (11), p.1942-1953

1992

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Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain

Molecular pharmacology, 1992-05, Vol.41 (5), p.914-922

1992

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4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors

Bioorganic & medicinal chemistry letters, 1999-05, Vol.9 (9), p.1285-1290

1999

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Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel

Journal of medicinal chemistry, 1990-05, Vol.33 (5), p.1296-1305

1990

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The effect of elastomeric liners on high-pressure liquid propellant combustion oscillations

Propellants, explosives, pyrotechnics, 1995-12, Vol.20 (6), p.311-321

1995

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3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1

Journal of medicinal chemistry, 2004-03, Vol.47 (7), p.1807-1822

2004

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Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype

Nature neuroscience, 2000-06, Vol.3 (6), p.587-592

2000

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Microstructural changes in coal during low temperature ashing

Fuel (Guildford), 1986-03, Vol.65 (3), p.321-326

1986

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Preclinical and clinical pharmacology of TPA023 B, a GABAA receptor α2/α3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011, Vol.25 (3), p.329-344

2011

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Modification of an oxygen bomb calorimeter to measure enthalpies of reaction of liquid metals

Review of scientific instruments, 1978-10, Vol.49 (10), p.1489-1490

Carling, R. W.

1978

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Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Journal of psychopharmacology (Oxford), 2011-03, Vol.25 (3), p.329-344

2011

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A Convenient Synthesis of 4-Alkylfuran-2-Acetic Acids

Synlett, 1993, Vol.1993 (1), p.40-40

1993

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MK-801 analogues: molecular properties required for recognition by the N-methyl-D-aspartate receptor

Progress in clinical and biological research, 1990, Vol.361, p.513

1990

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Studies on the synthesis of gloeosporone - synthesis of the proposed 2,8-disubstituted oxocane structure

Tetrahedron letters, 1986, Vol.27 (50), p.6133-6136

1986

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A Heat Pump and Thermal Storage System for Solar Heating and Cooling Based on the Reaction of Calcium Chloride and Methanol Vapor

Journal of solar energy engineering, 1980-02, Vol.102 (1), p.59-65

1980

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Discovery of Imidazo[1,2-b][1,2,4]triazines as GABA sub(A) alpha 2/3 Subtype Selective Agonists for the Treatment of Anxiety

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1235-1238

2006

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7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy) -3-(2-fluorophenyl)- 1,2,4-triazolo [4,3-b] pyridazine: A Functionally Selective gamma -Aminobutyric Acid sub(A) (GABA sub(A)) alpha 2/ alpha 3-Subtype Selective Agonist That Exhibits Potent Anxiolytic Activity but Is Not Sedating in Animal Models

Journal of medicinal chemistry, 2005-11, Vol.48 (23), p.7089-7092

2005

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Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products

Effect of Plasma Protein Binding on in Vivo Activity and Brain Penetration of Glycine/NMDA Receptor Antagonists

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor

4-Substituted-3-phenylquinolin-2(1H)-ones: Acidic and Nonacidic Glycine Site N-Methyl-d-aspartate Antagonists with in Vivo Activity

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor

Characterization of the binding of [3H]L-689,560, an antagonist for the glycine site on the N-methyl-D-aspartate receptor, to rat brain membranes

3-Nitro-3,4-dihydro-2(1H)quinolones. Excitatory amino acid antagonists acting at glycine-site NMDA and (RS)-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors

2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor

Kynurenic acid analogues with improved affinity and selectivity for the glycine site on the N-methyl-D-aspartate receptor from rat brain

4-N-linked-heterocyclic piperidine derivatives with high affinity and selectivity for human dopamine D4 receptors

Role of hydrogen bonding in ligand interaction with the N-methyl-D-aspartate receptor ion channel

The effect of elastomeric liners on high-pressure liquid propellant combustion oscillations

3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1

Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor α1 subtype

Microstructural changes in coal during low temperature ashing

Preclinical and clinical pharmacology of TPA023 B, a GABAA receptor α2/α3 subtype-selective partial agonist

Modification of an oxygen bomb calorimeter to measure enthalpies of reaction of liquid metals

Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

A Convenient Synthesis of 4-Alkylfuran-2-Acetic Acids

MK-801 analogues: molecular properties required for recognition by the N-methyl-D-aspartate receptor

Studies on the synthesis of gloeosporone - synthesis of the proposed 2,8-disubstituted oxocane structure

A Heat Pump and Thermal Storage System for Solar Heating and Cooling Based on the Reaction of Calcium Chloride and Methanol Vapor

Discovery of Imidazo[1,2-b][1,2,4]triazines as GABA sub(A) alpha 2/3 Subtype Selective Agonists for the Treatment of Anxiety

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