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A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generation c-ABL therapy

Haematologica (Roma), 2015-07, Vol.100 (7), p.898-904

2015

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Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance

Molecular pharmacology, 1994-05, Vol.45 (5), p.908-915

1994

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Feasibility study of a solar photovoltaic adaptable refrigeration kit for remote areas in developing countries

2015 International Conference on Clean Electrical Power (ICCEP), 2015, p.701-708

2015

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The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule

Cancer chemotherapy and pharmacology, 1999, Vol.43 (3), p.241-246

1999

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Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells

British journal of cancer, 1997, Vol.75 (6), p.878-883

1997

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Biological profile of FCE 24517, a novel benzoyl mustard analogue of distamycin A

British journal of cancer, 1991-12, Vol.64 (6), p.1047-1050

1991

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Characterisation of a LoVo subline resistant to a benzoyl mustard derivative of distamycin A (FCE 24517)

British journal of cancer, 1993-11, Vol.68 (5), p.916-919

1993

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Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine)

British journal of cancer, 1995-12, Vol.72 (6), p.1504-1508

1995

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Morpholinylanthracyclines : cytotoxicity and antitumor activity of differently modified derivatives

Investigational new drugs, 1996-01, Vol.14 (2), p.139-146

1996

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Phase I/II trial of nemorubicin hydrochloride in combination with cisplatin is supported by new preclinical evidences of its mechanism of action

Journal of clinical oncology, 2006-06, Vol.24 (18_suppl), p.14116-14116

2006

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Cytotoxic halogenoacrylic derivatives of distamycin A

Bioorganic & medicinal chemistry letters, 2000-06, Vol.10 (11), p.1269-1272

2000

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Temperature influences both cytotoxicity and DNA nicking efficiency of the antitumor distamycin analogue FCE24517

Anticancer research, 1994-01, Vol.14 (1A), p.189

1994

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Sequence-specific DNA alkylation of novel tallimustine derivatives

Anti-cancer drug design, 1998-04, Vol.13 (3), p.193

1998

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Pharmacological and toxicological aspects of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548) : A novel antineoplastic agent

Cancer research (Chicago, Ill.), 2001-03, Vol.61 (5), p.1983-1990

2001

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Phenyl sulfur mustard derivatives of distamycin A

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (15), p.1653-1656

2000

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Novel phenyl nitrogen mustard and half-mustard derivatives of amidino-modified distamycin

Bioorganic & medicinal chemistry letters, 1997-12, Vol.7 (23), p.2979-2984

1997

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Structure-activity relationship of novel tallimustine derivatives: synthesis and antitumor activity

Bioorganic & medicinal chemistry letters, 1996-06, Vol.6 (11), p.1247-1252

1996

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Novel phenyl nitrogen mustard and half-mustard derivatives of distamycin A

Bioorganic & medicinal chemistry letters, 1997-12, Vol.7 (23), p.2985-2990

1997

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Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2226-2230

1991

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Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives

Bioorganic & medicinal chemistry letters, 1996-03, Vol.6 (6), p.671-674

1996

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Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins

Bioorganic & medicinal chemistry letters, 1997-04, Vol.7 (7), p.847-850

1997

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Antiproliferative properties of flavone acetic acid (NSC 347512) (LM 975), a new anticancer agent

European journal of cancer & clinical oncology, 1987-10, Vol.23 (10), p.1529-1535

1987

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The alkylating antitumor drug tallimustine does not induce DNA repair

Anticancer research, 1996-11, Vol.16 (6B), p.3779

1996

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Novel anthracycline analogs

Cancer treatment reviews, 1990-09, Vol.17 (2), p.133-138

1990

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DNA damage and cytotoxicity of mitoxantrone and doxorubicin in doxorubicin-sensitive and -resistant human colon carcinoma cells

Cancer chemotherapy and pharmacology, 1990, Vol.25 (6), p.430-434

1990

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A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generation c-ABL therapy

Influence of structural modifications at the 3' and 4' positions of doxorubicin on the drug ability to trap topoisomerase II and to overcome multidrug resistance

Feasibility study of a solar photovoltaic adaptable refrigeration kit for remote areas in developing countries

The antitumor efficacy of cytotoxic drugs is potentiated by treatment with PNU 145156E, a growth-factor-complexing molecule

Estimation of the haematological toxicity of minor groove alkylators using tests on human cord blood cells

Biological profile of FCE 24517, a novel benzoyl mustard analogue of distamycin A

Characterisation of a LoVo subline resistant to a benzoyl mustard derivative of distamycin A (FCE 24517)

Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine)

Morpholinylanthracyclines : cytotoxicity and antitumor activity of differently modified derivatives

Phase I/II trial of nemorubicin hydrochloride in combination with cisplatin is supported by new preclinical evidences of its mechanism of action

Cytotoxic halogenoacrylic derivatives of distamycin A

Temperature influences both cytotoxicity and DNA nicking efficiency of the antitumor distamycin analogue FCE24517

Sequence-specific DNA alkylation of novel tallimustine derivatives

Pharmacological and toxicological aspects of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin (PNU-159548) : A novel antineoplastic agent

Phenyl sulfur mustard derivatives of distamycin A

Novel phenyl nitrogen mustard and half-mustard derivatives of amidino-modified distamycin

Structure-activity relationship of novel tallimustine derivatives: synthesis and antitumor activity

Novel phenyl nitrogen mustard and half-mustard derivatives of distamycin A

Purine and 1-deazapurine ribonucleosides and deoxyribonucleosides: synthesis and biological activity

Synthesis and antitumor activity of a new class of water soluble camptothecin derivatives

Synthesis and cytotoxic activity of alkylidene- and alkyl-substituted camptothecins

Antiproliferative properties of flavone acetic acid (NSC 347512) (LM 975), a new anticancer agent

The alkylating antitumor drug tallimustine does not induce DNA repair

Novel anthracycline analogs

DNA damage and cytotoxicity of mitoxantrone and doxorubicin in doxorubicin-sensitive and -resistant human colon carcinoma cells

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