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Signaling pathways that regulate basal ABC transporter activity at the blood- brain barrier

Current pharmaceutical design, 2014-03, Vol.20 (10), p.1463

2014

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Nitric oxide reverses drug resistance by inhibiting ATPase activity of p-glycoprotein in human multi-drug resistant cancer cells

Biochimica et biophysica acta. General subjects, 2018-12, Vol.1862 (12), p.2806-2814

2018

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Reversal of drug resistance by JS-K and nitric oxide in ABCB1- and ABCG2-expressing multi-drug resistant human tumor cells

Biomedicine & pharmacotherapy, 2019-12, Vol.120, p.109468-109468, Article 109468

2019

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Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (39), p.15930-15935

2012

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Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling

Molecular pharmacology, 2017-04, Vol.91 (4), p.373-382

2017

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A Role for iNOS in Erastin Mediated Reduction of P-Glycoprotein Transport Activity

Cancers, 2024-05, Vol.16 (9), p.1733

2024

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NCX-4040, a Unique Nitric Oxide Donor, Induces Reversal of Drug-Resistance in Both ABCB1- and ABCG2-Expressing Multidrug Human Cancer Cells

Cancers, 2021-04, Vol.13 (7), p.1680

2021

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1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells

Journal of neurochemistry, 2012-12, Vol.123 (6), p.944-953

2012

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Ferroptosis-Mediated Cell Death Induced by NCX4040, The Non-Steroidal Nitric Oxide Donor, in Human Colorectal Cancer Cells: Implications in Therapy

Cells (Basel, Switzerland), 2023-06, Vol.12 (12), p.1626

2023

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Effects of Deep Hypothermic Circulatory Arrest on the Blood Brain Barrier in a Cardiopulmonary Bypass Model – A Pilot Study

Heart, lung & circulation, 2014-10, Vol.23 (10), p.981-984

2014

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Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers

The Journal of neuroscience, 2014-06, Vol.34 (25), p.8585-8593

2014

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Effect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier

Environmental health perspectives, 2020-03, Vol.128 (3), p.37002

2020

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Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier

Toxicological sciences, 2019-06, Vol.169 (2), p.475-484

2019

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Identification of a Specific Motif of the DSS1 Protein Required for Proteasome Interaction and p53 Protein Degradation

Journal of molecular biology, 2008-11, Vol.383 (3), p.693-712

2008

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2,4,6-Tribromophenol Exposure Decreases P-Glycoprotein Transport at the Blood-Brain Barrier

Toxicological sciences, 2019-10, Vol.171 (2), p.463-472

2019

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PPAR-α, a lipid-sensing transcription factor, regulates blood–brain barrier efflux transporter expression

Journal of cerebral blood flow and metabolism, 2017-04, Vol.37 (4), p.1199-1212

2017

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Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood–brain barrier

Journal of cerebral blood flow and metabolism, 2018-05, Vol.38 (5), p.857-868

2018

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Mrp1 is Essential for Sphingolipid Signaling to P-Glycoprotein in Mouse Blood–Brain and Blood–Spinal Cord Barriers

Journal of cerebral blood flow and metabolism, 2013-03, Vol.33 (3), p.381-388

2013

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Selective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model

Neuroscience letters, 2017-02, Vol.639, p.103-113

2017

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Arsenic exposure in utero exacerbates skin cancer response in adulthood with contemporaneous distortion of tumor stem cell dynamics

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (20), p.8278-8285

2008

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Assessment of Ex Vivo Transport Function in Isolated Rodent Brain Capillaries

Current Protocols in Pharmacology, 2017-03, Vol.76 (1), p.7.16.1-7.16.16

2017

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Identification of Dss1 as a 12-O-Tetradecanoylphorbol-13-acetate-responsive Gene Expressed in Keratinocyte Progenitor Cells, with Possible Involvement in Early Skin Tumorigenesis

The Journal of biological chemistry, 2003-01, Vol.278 (3), p.1758-1768

2003

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Gene-Environment Interactions: Fundamentals of Ecogenetics

Environmental Health Perspectives, 2006-06, Vol.114 (6), p.A382-A382

Cannon, Ronald E.

2006

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NITRIC OXIDE REVERSES DRUG RESISTANCE BY INHIBITING ATPASE ACTIVITY OF P-GLYCOPROTEIN IN HUMAN MULTI-DRUG RESISTANT CANCER CELLS

Biochimica et biophysica acta. General subjects, 2018-09, Vol.1862 (12), p.2806-2814

2018

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Retrotransposition‐Competent Human LINE‐1 Induces Apoptosis in Cancer Cells With Intact p53

BioMed research international, 2004, Vol.2004 (4), p.185-194

2004

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Signaling pathways that regulate basal ABC transporter activity at the blood- brain barrier

Nitric oxide reverses drug resistance by inhibiting ATPase activity of p-glycoprotein in human multi-drug resistant cancer cells

Reversal of drug resistance by JS-K and nitric oxide in ABCB1- and ABCG2-expressing multi-drug resistant human tumor cells

Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain

Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling

A Role for iNOS in Erastin Mediated Reduction of P-Glycoprotein Transport Activity

NCX-4040, a Unique Nitric Oxide Donor, Induces Reversal of Drug-Resistance in Both ABCB1- and ABCG2-Expressing Multidrug Human Cancer Cells

1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells

Ferroptosis-Mediated Cell Death Induced by NCX4040, The Non-Steroidal Nitric Oxide Donor, in Human Colorectal Cancer Cells: Implications in Therapy

Effects of Deep Hypothermic Circulatory Arrest on the Blood Brain Barrier in a Cardiopulmonary Bypass Model – A Pilot Study

Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers

Effect of GenX on P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 at the Blood-Brain Barrier

Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier

Identification of a Specific Motif of the DSS1 Protein Required for Proteasome Interaction and p53 Protein Degradation

2,4,6-Tribromophenol Exposure Decreases P-Glycoprotein Transport at the Blood-Brain Barrier

PPAR-α, a lipid-sensing transcription factor, regulates blood–brain barrier efflux transporter expression

Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood–brain barrier

Mrp1 is Essential for Sphingolipid Signaling to P-Glycoprotein in Mouse Blood–Brain and Blood–Spinal Cord Barriers

Selective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model

Arsenic exposure in utero exacerbates skin cancer response in adulthood with contemporaneous distortion of tumor stem cell dynamics

Assessment of Ex Vivo Transport Function in Isolated Rodent Brain Capillaries

Identification of Dss1 as a 12-O-Tetradecanoylphorbol-13-acetate-responsive Gene Expressed in Keratinocyte Progenitor Cells, with Possible Involvement in Early Skin Tumorigenesis

Gene-Environment Interactions: Fundamentals of Ecogenetics

NITRIC OXIDE REVERSES DRUG RESISTANCE BY INHIBITING ATPASE ACTIVITY OF P-GLYCOPROTEIN IN HUMAN MULTI-DRUG RESISTANT CANCER CELLS

Retrotransposition‐Competent Human LINE‐1 Induces Apoptosis in Cancer Cells With Intact p53

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