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Critical pathogenic events underlying progression of neurodegeneration in glaucoma

Progress in retinal and eye research, 2012-11, Vol.31 (6), p.702-719

Calkins, David J.

2012

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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

Human molecular genetics, 2011-12, Vol.20 (23), p.4515-4529

2011

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Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

Biochimica et biophysica acta, 2011-04, Vol.1812 (4), p.507-513

2011

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Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

Neuroscience, 2011-03, Vol.176, p.1-11

2011

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

Human molecular genetics, 2011-04, Vol.20 (7), p.1438-1455

2011

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The Microbead Occlusion Model: A Paradigm for Induced Ocular Hypertension in Rats and Mice

Investigative ophthalmology & visual science, 2010-01, Vol.51 (1), p.207-216

2010

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The Neurovascular Unit in Glaucomatous Neurodegeneration

Frontiers in cell and developmental biology, 2020-06, Vol.8, p.452-452

2020

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Solving neurodegeneration: common mechanisms and strategies for new treatments

Molecular neurodegeneration, 2022-03, Vol.17 (1), p.23-23, Article 23

2022

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Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

Human molecular genetics, 2012-01, Vol.21 (2), p.406-420

2012

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miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer

Breast cancer research : BCR, 2017-12, Vol.19 (1), p.133-133, Article 133

2017

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Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

Journal of Alzheimer's disease, 2010-01, Vol.20 Suppl 2, p.S609

2010

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Mitochondria-targeted catalase reduces abnormal APP processing, amyloid production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension

Human molecular genetics, 2012-07, Vol.21 (13), p.2973-2990

2012

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Distal axonopathy with structural persistence in glaucomatous neurodegeneration

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (11), p.5196-5201

2010

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Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics

Biochimica et biophysica acta, 2012-05, Vol.1822 (5), p.639-649

2012

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The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease

Antioxidants & redox signaling, 2009-03, Vol.11 (3), p.497

2009

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Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection

The Journal of neuroscience, 2014-02, Vol.34 (9), p.3161-3170

2014

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Women in visual neural regeneration research

Neural regeneration research, 2025-02, Vol.20 (2), p.489-490

2025

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Retinal astrocyte morphology predicts integration of vascular and neuronal architecture

Frontiers in neuroscience, 2023-08, Vol.17, p.1244679-1244679

2023

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Early reduction of microglia activation by irradiation in a model of chronic glaucoma

PloS one, 2012-08, Vol.7 (8), p.e43602-e43602

2012

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Physicochemical and toxicological profiling of ash from the 2010 and 2011 eruptions of Eyjafjallajökull and Grímsvötn volcanoes, Iceland using a rapid respiratory hazard assessment protocol

Environmental research, 2013-11, Vol.127, p.63-73

2013

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Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration

Glia, 2014-09, Vol.62 (9), p.1435-1451

2014

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Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis

The Journal of biological chemistry, 2003-04, Vol.278 (14), p.12029-12038

2003

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Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension

Redox biology, 2021-06, Vol.42, p.101883-101883, Article 101883

2021

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The challenge of regenerative therapies for the optic nerve in glaucoma

Experimental eye research, 2017-04, Vol.157, p.28-33

2017

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Insulin Signaling as a Therapeutic Target in Glaucomatous Neurodegeneration

International journal of molecular sciences, 2021-04, Vol.22 (9), p.4672

2021

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Critical pathogenic events underlying progression of neurodegeneration in glaucoma

Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

Neurodegeneration in glaucoma: progression and calcium-dependent intracellular mechanisms

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

The Microbead Occlusion Model: A Paradigm for Induced Ocular Hypertension in Rats and Mice

The Neurovascular Unit in Glaucomatous Neurodegeneration

Solving neurodegeneration: common mechanisms and strategies for new treatments

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer

Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

Mitochondria-targeted catalase reduces abnormal APP processing, amyloid production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension

Distal axonopathy with structural persistence in glaucomatous neurodegeneration

Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: Implications to mitochondria-targeted antioxidant therapeutics

The Nrf2/ARE pathway as a potential therapeutic target in neurodegenerative disease

Absence of transient receptor potential vanilloid-1 accelerates stress-induced axonopathy in the optic projection

Women in visual neural regeneration research

Retinal astrocyte morphology predicts integration of vascular and neuronal architecture

Early reduction of microglia activation by irradiation in a model of chronic glaucoma

Physicochemical and toxicological profiling of ash from the 2010 and 2011 eruptions of Eyjafjallajökull and Grímsvötn volcanoes, Iceland using a rapid respiratory hazard assessment protocol

Activation of the TRPV1 cation channel contributes to stress-induced astrocyte migration

Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis

Retinal oxidative stress activates the NRF2/ARE pathway: An early endogenous protective response to ocular hypertension

The challenge of regenerative therapies for the optic nerve in glaucoma

Insulin Signaling as a Therapeutic Target in Glaucomatous Neurodegeneration

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