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Cancer therapy: Targeting mitochondria and other sub-cellular organelles

Current pharmaceutical design, 2014-01, Vol.20 (2), p.201-222

2014

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Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

Nature communications, 2021-12, Vol.12 (1), p.7325-7325, Article 7325

2021

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In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug Development

Journal of Immunology Research, 2020, Vol.2020 (2020), p.1-14

2020

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An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model

Frontiers in immunology, 2019-03, Vol.10, p.526-526

2019

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Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Frontiers in immunology, 2017-12, Vol.8, p.1780-1780

2017

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Phage Display Derived IgNAR V Region Binding Domains for Therapeutic Development

Current pharmaceutical design, 2016-01, Vol.22 (43), p.6519-6526

2016

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In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Frontiers in immunology, 2017-10, Vol.8, p.1361-1361

2017

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Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic Development

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2446, p.19

2022

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Next-generation flexible formats of VNAR domains expand the drug platform's utility and developability

Biochemical Society transactions, 2018-12, Vol.46 (6), p.1559-1565

2018

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In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties

Methods in molecular biology (Clifton, N.J.), 2020-01, Vol.2070, p.115

2020

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Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

Translational vision science & technology, 2019-09, Vol.8 (5), p.11

2019

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Derivative of aminoresin as potent anti-virulence agent: Synthesis, spectral (FT-IR, UV, NMR) analysis, molecular docking, effect of polar solvation dynamics, and quantum chemical investigation

Journal of molecular structure, 2024-01, Vol.1295, p.136744, Article 136744

2024

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Overcoming Challenges in Providing Radiation Therapy to Patients With Cancer in Nigeria and Experience in the National Hospital Abuja, Nigeria

JCO global oncology, 2020-11, Vol.6 (6), p.1232-1236

2020

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Elucidating the structural basis for the enhanced antifungal activity of amide derivative against Candida albicans: a comprehensive computational investigation

In silico pharmacology, 2024-05, Vol.12 (1), p.48-48, Article 48

2024

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Prevalence of refractive error in paediatric age group in a tertiary eye center in Onitsha, south east, Nigeria

International Journal of Medical and Health Sciences Research, 2023-05, Vol.10 (1), p.18-27

2023

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Cancer therapy: Targeting mitochondria and other sub-cellular organelles

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

In Vitro ELISA and Cell-Based Assays Confirm the Low Immunogenicity of VNAR Therapeutic Constructs in a Mouse Model of Human RA: An Encouraging Milestone to Further Clinical Drug Development

An Anti-hTNF-α Variable New Antigen Receptor Format Demonstrates Superior in vivo Preclinical Efficacy to Humira® in a Transgenic Mouse Autoimmune Polyarthritis Disease Model

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralizing Potency and Multifunctionality, Generated for Therapeutic Development

Phage Display Derived IgNAR V Region Binding Domains for Therapeutic Development

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Overview, Generation, and Significance of Variable New Antigen Receptors (VNARs) as a Platform for Drug and Diagnostic Development

Next-generation flexible formats of VNAR domains expand the drug platform's utility and developability

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties

Uveitis Therapy With Shark Variable Novel Antigen Receptor Domains Targeting Tumor Necrosis Factor Alpha or Inducible T-Cell Costimulatory Ligand

Derivative of aminoresin as potent anti-virulence agent: Synthesis, spectral (FT-IR, UV, NMR) analysis, molecular docking, effect of polar solvation dynamics, and quantum chemical investigation

Overcoming Challenges in Providing Radiation Therapy to Patients With Cancer in Nigeria and Experience in the National Hospital Abuja, Nigeria

Elucidating the structural basis for the enhanced antifungal activity of amide derivative against Candida albicans: a comprehensive computational investigation

Prevalence of refractive error in paediatric age group in a tertiary eye center in Onitsha, south east, Nigeria

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