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Targeting glutamine metabolism as a therapeutic strategy for cancer

Experimental and Molecular Medicine, 2023, 55(0), , pp.706-715

2023

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Tumor lactic acid: a potential target for cancer therapy

Archives of Pharmacal Research, 2023, 46(2), , pp.90-110

Byun, Jun-Kyu

2023

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Macropinocytosis is an alternative pathway of cysteine acquisition and mitigates sorafenib-induced ferroptosis in hepatocellular carcinoma

Journal of experimental & clinical cancer research, 2022-03, Vol.41 (1), p.98-98, Article 98

2022

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Oncogenic KRAS signaling activates mTORC1 through COUP‐TFII‐mediated lactate production

EMBO reports, 2019-06, Vol.20 (6), p.n/a

2019

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Retinoic acid‐related orphan receptor alpha reprograms glucose metabolism in glutamine‐deficient hepatoma cells

Hepatology (Baltimore, Md.), 2015-03, Vol.61 (3), p.953-964

2015

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A Positive Feedback Loop between Sestrin2 and mTORC2 Is Required for the Survival of Glutamine-Depleted Lung Cancer Cells

Cell reports (Cambridge), 2017-07, Vol.20 (3), p.586-599

2017

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Melatonin inhibits glycolysis in hepatocellular carcinoma cells by downregulating mitochondrial respiration and mTORC1 activity

BMB Reports, 2022, 55(9), , pp.459-464

2022

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Glutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages

Experimental & molecular medicine, 2024-05, Vol.56 (5), p.1123-1136

2024

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Ulmus davidiana 60% edible ethanolic extract for prevention of pericyte apoptosis in diabetic retinopathy

Frontiers in endocrinology (Lausanne), 2023-05, Vol.14, p.1138676-1138676

2023

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Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

Scientific reports, 2016-07, Vol.6 (1), p.30846-30846, Article 30846

2016

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Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

Molecular cell, 2020-11, Vol.80 (4), p.592-606.e8

2020

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N-methyl-D-aspartate receptors induce M1 polarization of macrophages: Feasibility of targeted imaging in inflammatory response in vivo

Cell & bioscience, 2023-03, Vol.13 (1), p.69-69, Article 69

2023

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Estrogen-related receptor γ is upregulated in liver cancer and its inhibition suppresses liver cancer cell proliferation via induction of p21 and p27

Experimental & molecular medicine, 2016-03, Vol.48 (3), p.e213-e213

2016

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Transcription Factor Eb Is Required for Macropinocytosis-Mediated Growth Recovery of Nutrient-Deprived Kras-Mutant Cells

Nutrients, 2018-11, Vol.10 (11), p.1638

2018

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Acesulfame potassium upregulates PD-L1 in HCC cells by attenuating autophagic degradation

Biochemical and biophysical research communications, 2024-06, Vol.711, p.149921, Article 149921

2024

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Plant-exclusive domain of trans-editing enzyme ProXp-ala confers dimerization and enhanced tRNA binding

The Journal of biological chemistry, 2022-09, Vol.298 (9), p.102255-102255, Article 102255

2022

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SGLT2 inhibitors prevent LPS-induced M1 macrophage polarization and alleviate inflammatory bowel disease by downregulating NHE1 expression

Inflammation research, 2023-11, Vol.72 (10-11), p.1981-1997

2023

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Lactate dehydrogenase-A is indispensable for vascular smooth muscle cell proliferation and migration

Biochemical and biophysical research communications, 2017-10, Vol.492 (1), p.41-47

2017

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Melatonin inhibits glycolysis in hepatocellular carcinoma cells by downregulating mitochondrial respiration and mTORC1 activity

BMB reports, 2022-09, Vol.55 (9), p.459-464

2022

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DN200434, an orally available inverse agonist of estrogen-related receptor γ, induces ferroptosis in sorafenib-resistant hepatocellular carcinoma

BMB Reports, 2022-11, Vol.55 (11), p.547-552

2022

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Manassantin A inhibits tumour growth under hypoxia through the activation of chaperone-mediated autophagy by modulating Hsp90 activity

British journal of cancer, 2023-04, Vol.128 (8), p.1491-1502

2023

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DN200434, an orally available inverse agonist of estrogen-related receptor γ, induces ferroptosis in sorafenib-resistant hepatocellular carcinoma

BMB reports, 2022-11, Vol.55 (11), p.547-552

2022

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Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2

Experimental and therapeutic medicine, 2020-06

2020

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Gemigliptin mitigates TGF-β-induced renal fibrosis through FGF21-mediated inhibition of the TGF-β/Smad3 signaling pathway

Biochemical and biophysical research communications, 2024-11, Vol.733, p.150425, Article 150425

2024

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Abstract 1922: Plant-exclusive domain of trans-editing enzyme ProX-ala confers dimerization and enhanced tRNA binding

The Journal of biological chemistry, 2023, Vol.299 (3), p.103615, Article 103615

2023

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Targeting glutamine metabolism as a therapeutic strategy for cancer

Tumor lactic acid: a potential target for cancer therapy

Macropinocytosis is an alternative pathway of cysteine acquisition and mitigates sorafenib-induced ferroptosis in hepatocellular carcinoma

Oncogenic KRAS signaling activates mTORC1 through COUP‐TFII‐mediated lactate production

Retinoic acid‐related orphan receptor alpha reprograms glucose metabolism in glutamine‐deficient hepatoma cells

A Positive Feedback Loop between Sestrin2 and mTORC2 Is Required for the Survival of Glutamine-Depleted Lung Cancer Cells

Melatonin inhibits glycolysis in hepatocellular carcinoma cells by downregulating mitochondrial respiration and mTORC1 activity

Glutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages

Ulmus davidiana 60% edible ethanolic extract for prevention of pericyte apoptosis in diabetic retinopathy

Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

N-methyl-D-aspartate receptors induce M1 polarization of macrophages: Feasibility of targeted imaging in inflammatory response in vivo

Estrogen-related receptor γ is upregulated in liver cancer and its inhibition suppresses liver cancer cell proliferation via induction of p21 and p27

Transcription Factor Eb Is Required for Macropinocytosis-Mediated Growth Recovery of Nutrient-Deprived Kras-Mutant Cells

Acesulfame potassium upregulates PD-L1 in HCC cells by attenuating autophagic degradation

Plant-exclusive domain of trans-editing enzyme ProXp-ala confers dimerization and enhanced tRNA binding

SGLT2 inhibitors prevent LPS-induced M1 macrophage polarization and alleviate inflammatory bowel disease by downregulating NHE1 expression

Lactate dehydrogenase-A is indispensable for vascular smooth muscle cell proliferation and migration

Melatonin inhibits glycolysis in hepatocellular carcinoma cells by downregulating mitochondrial respiration and mTORC1 activity

DN200434, an orally available inverse agonist of estrogen-related receptor γ, induces ferroptosis in sorafenib-resistant hepatocellular carcinoma

Manassantin A inhibits tumour growth under hypoxia through the activation of chaperone-mediated autophagy by modulating Hsp90 activity

DN200434, an orally available inverse agonist of estrogen-related receptor γ, induces ferroptosis in sorafenib-resistant hepatocellular carcinoma

Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2

Gemigliptin mitigates TGF-β-induced renal fibrosis through FGF21-mediated inhibition of the TGF-β/Smad3 signaling pathway

Abstract 1922: Plant-exclusive domain of trans-editing enzyme ProX-ala confers dimerization and enhanced tRNA binding

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