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1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0 2,6 ]heptanes as New Potent Muscarinic M 1 Agonists: Structure−Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3-Aryl-2-propyn-1-ylthio Derivatives

Journal of medicinal chemistry, 1999-06, Vol.42 (11), p.1999-2006

1999

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1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.02,6]heptanes as New Potent Muscarinic M1 Agonists: Structure−Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3-Aryl-2-propyn-1-ylthio Derivatives

Journal of medicinal chemistry, 1999-06, Vol.42 (11), p.1999-2006

1999

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450088-S, a ring-opened prodrug of a 1,4-benzodiazepine, inhibited [3H]flunitrazepam labeling of rat cerebral cortex in vivo

Drug development research, 1983, Vol.3 (1), p.67-73

1983

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Amantadine for weight gain associated with olanzapine treatment

European neuropsychopharmacology, 2005, Vol.15 (1), p.13-21

2005

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Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats

European journal of pharmacology, 2015-10, Vol.764, p.30-37

2015

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Antagonism by olanzapine of dopamine D1, serotonin 2, muscarinic, histamine H 1 and α1-adrenergic receptors in vitro

Schizophrenia research, 1999, Vol.37 (1), p.107-122

1999

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Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and α1-adrenergic receptors in vitro

Schizophrenia research, 1999-05, Vol.37 (1), p.107-122

1999

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Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection

Pharmacological reviews, 2008-09, Vol.60 (3), p.358-403

2008

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Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates

PloS one, 2015-04, Vol.10 (4), p.e0122722-e0122722

2015

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Arachidonic Acid Release in Cell Lines Transfected with Muscarinic Receptors

Cellular signalling, 1999-06, Vol.11 (6), p.405-413

1999

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Arachidonic Acid Release in Cell Lines Transfected with Muscarinic Receptors: A Simple Functional Assay to Determine Response of Agonists

Cellular signalling, 1999-06, Vol.11 (6), p.405-413

1999

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Atomoxetine Increases Extracellular Levels of Norepinephrine and Dopamine in Prefrontal Cortex of Rat: A Potential Mechanism for Efficacy in Attention Deficit/Hyperactivity Disorder

Neuropsychopharmacology (New York, N.Y.), 2002-11, Vol.27 (5), p.699-711

2002

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Biopharmaceutical Characterization, Metabolism, and Brain Penetration of the Triple Reuptake Inhibitor Amitifadine

Drug metabolism letters, 2013-03, Vol.7 (1), p.23-33

2013

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Biopharmaceutical characterization, metabolism, and brain penetration of the triple reuptake inhibitor amitifadine

Drug metabolism letters, 2013-03, Vol.7 (1), p.23

2013

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Brain region and dose effects of an olanzapine/fluoxetine combination on extracellular monoamine concentrations in the rat

Neuropharmacology, 2004-02, Vol.46 (2), p.232-242

2004

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Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic

The Journal of pharmacology and experimental therapeutics, 1997-05, Vol.281 (2), p.876

1997

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The cannabinoid CB 1 receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus

European journal of pharmacology, 2001, Vol.426 (3), p.R3-R4

2001

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The cannabinoid CB1 receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus

European journal of pharmacology, 2001-08, Vol.426 (3), p.R3-R4

2001

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Case history: the discovery of fluoxetine hydrochloride (Prozac)

Nature reviews. Drug discovery, 2005-09, Vol.4 (9), p.764-774

2005

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The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions

British journal of pharmacology, 2003-02, Vol.138 (4), p.544-553

2003

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Chapter 1. Dopaminergic Approaches to Antipsychotic Agents

Annual Reports in Medicinal Chemistry, 1998, Vol.33, p.1-10

1998

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Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

The Journal of pharmacology and experimental therapeutics, 2002-06, Vol.301 (3), p.1020-1024

2002

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ChemInform Abstract: Therapeutic Opportunities for Muscarinic Receptors in the Central Nervous System

ChemInform, 2001-01, Vol.32 (5), p.no-no

2001

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Cholinergic dilation of cerebral blood vessels is abolished in M 5 muscarinic acetylcholine receptor knockout mice

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.14096-14101

2001

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Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice

Proceedings of the National Academy of Sciences - PNAS, 2001-11, Vol.98 (24), p.14096-14101

2001

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1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.0 2,6 ]heptanes as New Potent Muscarinic M 1 Agonists: Structure−Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3-Aryl-2-propyn-1-ylthio Derivatives

1-(1,2,5-Thiadiazol-4-yl)-4-azatricyclo[2.2.1.02,6]heptanes as New Potent Muscarinic M1 Agonists: Structure−Activity Relationship for 3-Aryl-2-propyn-1-yloxy and 3-Aryl-2-propyn-1-ylthio Derivatives

450088-S, a ring-opened prodrug of a 1,4-benzodiazepine, inhibited [3H]flunitrazepam labeling of rat cerebral cortex in vivo

Amantadine for weight gain associated with olanzapine treatment

Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats

Antagonism by olanzapine of dopamine D1, serotonin 2, muscarinic, histamine H 1 and α1-adrenergic receptors in vitro

Antagonism by olanzapine of dopamine D1, serotonin2, muscarinic, histamine H1 and α1-adrenergic receptors in vitro

Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection

Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates

Arachidonic Acid Release in Cell Lines Transfected with Muscarinic Receptors

Arachidonic Acid Release in Cell Lines Transfected with Muscarinic Receptors: A Simple Functional Assay to Determine Response of Agonists

Atomoxetine Increases Extracellular Levels of Norepinephrine and Dopamine in Prefrontal Cortex of Rat: A Potential Mechanism for Efficacy in Attention Deficit/Hyperactivity Disorder

Biopharmaceutical Characterization, Metabolism, and Brain Penetration of the Triple Reuptake Inhibitor Amitifadine

Biopharmaceutical characterization, metabolism, and brain penetration of the triple reuptake inhibitor amitifadine

Brain region and dose effects of an olanzapine/fluoxetine combination on extracellular monoamine concentrations in the rat

Butylthio[2.2.2] (NNC 11-1053/LY297802): an orally active muscarinic agonist analgesic

The cannabinoid CB 1 receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus

The cannabinoid CB1 receptor antagonist SR141716A increases norepinephrine outflow in the rat anterior hypothalamus

Case history: the discovery of fluoxetine hydrochloride (Prozac)

The CB1 receptor antagonist SR141716A selectively increases monoaminergic neurotransmission in the medial prefrontal cortex: implications for therapeutic actions

Chapter 1. Dopaminergic Approaches to Antipsychotic Agents

Characterization of a novel endocannabinoid, virodhamine, with antagonist activity at the CB1 receptor

ChemInform Abstract: Therapeutic Opportunities for Muscarinic Receptors in the Central Nervous System

Cholinergic dilation of cerebral blood vessels is abolished in M 5 muscarinic acetylcholine receptor knockout mice

Cholinergic dilation of cerebral blood vessels is abolished in M5 muscarinic acetylcholine receptor knockout mice

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