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Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in Pseudomonas aeruginosa

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (31), p.1

2021

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Antimicrobial susceptibility of Mycobacterium abscessus and treatment of pulmonary and extra-pulmonary infections

Clinical microbiology and infection, 2024-06, Vol.30 (6), p.718-725

2024

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A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

Antimicrobial agents and chemotherapy, 2022-01, Vol.66 (1), p.e0178921-e0178921

2022

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In vitro efficacy of combinations of antibiotics used in clinical practice on clinical isolates of Helicobacter pylori

Helicobacter (Cambridge, Mass.), 2024-05, Vol.29 (3), p.e13081-n/a

2024

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Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling

Antimicrobial agents and chemotherapy, 2023-10, Vol.67 (10), p.e0048023-e0048023

2023

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Salicylidene Acylhydrazides and Hydroxyquinolines Act as Inhibitors of Type Three Secretion Systems in Pseudomonas aeruginosa by Distinct Mechanisms

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6), p.515.e1-515.e4

2017

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Increased Susceptibility of Pseudomonas aeruginosa to Macrolides and Ketolides in Eukaryotic Cell Culture Media and Biological Fluids Due to Decreased Expression of oprM and Increased Outer-Membrane Permeability

Clinical infectious diseases, 2012-08, Vol.55 (4), p.534-542

2012

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Pharmacodynamic Evaluation of the Intracellular Activity of Antibiotics towards Pseudomonas aeruginosa PAO1 in a Model of THP-1 Human Monocytes

Antimicrobial Agents and Chemotherapy, 2013-05, Vol.57 (5), p.2310-2318

2013

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Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

Antimicrobial agents and chemotherapy, 2019-07, Vol.63 (7)

2019

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Lipid Nanoparticles Loaded with Farnesol or Geraniol to Enhance the Susceptibility of E. coli MCR-1 to Colistin

Pharmaceutics, 2021-11, Vol.13 (11), p.1849

2021

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Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes

Antimicrobial agents and chemotherapy, 2015-01, Vol.59 (1), p.258-268

2015

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PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo

Frontiers in pharmacology, 2022-03, Vol.13, p.842921-842921

2022

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New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4420-4430

2014

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Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation

The Journal of infectious diseases, 2016-10, Vol.214 (7), p.1105-1116

2016

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Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains

EBioMedicine, 2019-03, Vol.41, p.479-487

2019

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Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010305-e1010305

2022

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In Vitro Models for the Study of the Intracellular Activity of Antibiotics

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2357, p.239

2021

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Pan‐azole‐resistant Meyerozyma guilliermondii clonal isolates harbouring a double F126L and L505F mutation in Erg11

Mycoses, 2024-03, Vol.67 (3), p.e13704-n/a

2024

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RX-P873, a Novel Protein Synthesis Inhibitor, Accumulates in Human THP-1 Monocytes and Is Active against Intracellular Infections by Gram-Positive (Staphylococcus aureus) and Gram-Negative (Pseudomonas aeruginosa) Bacteria

Antimicrobial agents and chemotherapy, 2015-08, Vol.59 (8), p.4750-4758

2015

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34: SYSTEMATIC IN VITRO INTERACTION STUDY ON CEFTAZIDIME/AVIBACTAM AND FOSFOMYCIN

Journal of global antimicrobial resistance., 2022-12, Vol.31, p.S21-S22

2022

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Correlation between cytotoxicity induced by Pseudomonas aeruginosa clinical isolates from acute infections and IL-1β secretion in a model of human THP-1 monocytes

Pathogens and disease, 2015-10, Vol.73 (7), p.ftv049

2015

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Role of MexAB-OprM in intrinsic resistance of Pseudomonas aeruginosa to temocillin and impact on the susceptibility of strains isolated from patients suffering from cystic fibrosis

Journal of antimicrobial chemotherapy, 2012-03, Vol.67 (3), p.771-775

2012

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In Vitro Models for the Study of the Intracellular Activity of Antibiotics

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1333, p.147

2016

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Semimechanistic Pharmacodynamic Modeling of Aztreonam‐Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug‐Resistant Gram‐Negative Bacteria

CPT: pharmacometrics and systems pharmacology, 2019-11, Vol.8 (11), p.815-824

2019

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Clinical Pharmacokinetics of Daptomycin

Clinical pharmacokinetics, 2021-03, Vol.60 (3), p.271-281

2021

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Outer membrane permeability: Antimicrobials and diverse nutrients bypass porins in Pseudomonas aeruginosa

Antimicrobial susceptibility of Mycobacterium abscessus and treatment of pulmonary and extra-pulmonary infections

A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

In vitro efficacy of combinations of antibiotics used in clinical practice on clinical isolates of Helicobacter pylori

Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling

Salicylidene Acylhydrazides and Hydroxyquinolines Act as Inhibitors of Type Three Secretion Systems in Pseudomonas aeruginosa by Distinct Mechanisms

Increased Susceptibility of Pseudomonas aeruginosa to Macrolides and Ketolides in Eukaryotic Cell Culture Media and Biological Fluids Due to Decreased Expression of oprM and Increased Outer-Membrane Permeability

Pharmacodynamic Evaluation of the Intracellular Activity of Antibiotics towards Pseudomonas aeruginosa PAO1 in a Model of THP-1 Human Monocytes

Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

Lipid Nanoparticles Loaded with Farnesol or Geraniol to Enhance the Susceptibility of E. coli MCR-1 to Colistin

Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes

PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo

New Amphiphilic Neamine Derivatives Active against Resistant Pseudomonas aeruginosa and Their Interactions with Lipopolysaccharides

Inhibition of the Injectisome and Flagellar Type III Secretion Systems by INP1855 Impairs Pseudomonas aeruginosa Pathogenicity and Inflammasome Activation

Quantitative contribution of efflux to multi-drug resistance of clinical Escherichia coli and Pseudomonas aeruginosa strains

Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa

In Vitro Models for the Study of the Intracellular Activity of Antibiotics

Pan‐azole‐resistant Meyerozyma guilliermondii clonal isolates harbouring a double F126L and L505F mutation in Erg11

RX-P873, a Novel Protein Synthesis Inhibitor, Accumulates in Human THP-1 Monocytes and Is Active against Intracellular Infections by Gram-Positive (Staphylococcus aureus) and Gram-Negative (Pseudomonas aeruginosa) Bacteria

34: SYSTEMATIC IN VITRO INTERACTION STUDY ON CEFTAZIDIME/AVIBACTAM AND FOSFOMYCIN

Correlation between cytotoxicity induced by Pseudomonas aeruginosa clinical isolates from acute infections and IL-1β secretion in a model of human THP-1 monocytes

Role of MexAB-OprM in intrinsic resistance of Pseudomonas aeruginosa to temocillin and impact on the susceptibility of strains isolated from patients suffering from cystic fibrosis

In Vitro Models for the Study of the Intracellular Activity of Antibiotics

Semimechanistic Pharmacodynamic Modeling of Aztreonam‐Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug‐Resistant Gram‐Negative Bacteria

Clinical Pharmacokinetics of Daptomycin

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