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Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes

Scientific reports, 2017-07, Vol.7 (1), p.4939-9, Article 4939

2017

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The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut–liver–kidney axis

The Journal of biological chemistry, 2017-09, Vol.292 (38), p.15789-15803

2017

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A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis

Scientific reports, 2019-08, Vol.9 (1), p.11879-19, Article 11879

2019

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Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

PloS one, 2015-11, Vol.10 (11), p.e0140569-e0140569

2015

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Deletion of Multispecific Organic Anion Transporter Oat1/Slc22a6 Protects against Mercury-induced Kidney Injury

The Journal of biological chemistry, 2011-07, Vol.286 (30), p.26391-26395

2011

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Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule

PloS one, 2012-07, Vol.7 (7), p.e40796-e40796

2012

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Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

Nature, 2003-11, Vol.426 (6964), p.247-254

2003

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Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling

Nature reviews. Nephrology, 2019-05, Vol.15 (5), p.301-316

2019

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Linkage of Organic Anion Transporter-1 to Metabolic Pathways through Integrated “Omics”-driven Network and Functional Analysis

The Journal of biological chemistry, 2011-09, Vol.286 (36), p.31522-31531

2011

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Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice

PloS one, 2010-05, Vol.5 (5), p.e10691-e10691

2010

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Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

Clinical journal of the American Society of Nephrology, 2015-11, Vol.10 (11), p.2039-2049

2015

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Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells

eLife, 2015-11, Vol.4

2015

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The organic anion transporter (OAT) family: a systems biology perspective

Physiological reviews, 2015-01, Vol.95 (1), p.83-123

2015

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Branching morphogenesis and kidney disease

Development (Cambridge), 2004-04, Vol.131 (7), p.1449-1462

2004

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In vitro culture of embryonic kidney rudiments and isolated ureteric buds

Methods in molecular biology (Clifton, N.J.), 2012, Vol.886, p.13

2012

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N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland

The Journal of biological chemistry, 2012-12, Vol.287 (50), p.42064-42070

2012

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Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues

Nature clinical practice. Nephrology, 2007-08, Vol.3 (8), p.443-448

2007

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The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

Clinical pharmacology and therapeutics, 2020-07, Vol.108 (1), p.40-53

2020

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A key role for the transporter OAT1 in systemic lipid metabolism

The Journal of biological chemistry, 2021-01, Vol.296, p.100603, Article 100603

2021

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Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning

The Journal of biological chemistry, 2020-02, Vol.295 (7), p.1829-1842

2020

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Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney

Developmental biology, 2004-11, Vol.275 (1), p.44-67

2004

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Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease

JCI insight, 2020-04, Vol.5 (7)

2020

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Changes in Global Gene Expression Patterns during Development and Maturation of the Rat Kidney

Proceedings of the National Academy of Sciences - PNAS, 2001-05, Vol.98 (10), p.5649-5654

2001

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The organic anion transporter family: from physiology to ontogeny and the clinic

American journal of physiology. Renal physiology, 2001-08, Vol.281 (2), p.F197-F205

2001

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Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members

Physiological genomics, 2009-07, Vol.38 (2), p.116-124

2009

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Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes

The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut–liver–kidney axis

A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis

Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs

Deletion of Multispecific Organic Anion Transporter Oat1/Slc22a6 Protects against Mercury-induced Kidney Injury

Organic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubule

Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis

Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling

Linkage of Organic Anion Transporter-1 to Metabolic Pathways through Integrated “Omics”-driven Network and Functional Analysis

Loss of the heparan sulfate sulfotransferase, Ndst1, in mammary epithelial cells selectively blocks lobuloalveolar development in mice

Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters

Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells

The organic anion transporter (OAT) family: a systems biology perspective

Branching morphogenesis and kidney disease

In vitro culture of embryonic kidney rudiments and isolated ureteric buds

N-Sulfation of Heparan Sulfate Regulates Early Branching Events in the Developing Mammary Gland

Drug and toxicant handling by the OAT organic anion transporters in the kidney and other tissues

The Systems Biology of Drug Metabolizing Enzymes and Transporters: Relevance to Quantitative Systems Pharmacology

A key role for the transporter OAT1 in systemic lipid metabolism

Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning

Spatiotemporal regulation of morphogenetic molecules during in vitro branching of the isolated ureteric bud: toward a model of branching through budding in the developing kidney

Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease

Changes in Global Gene Expression Patterns during Development and Maturation of the Rat Kidney

The organic anion transporter family: from physiology to ontogeny and the clinic

Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members

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