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Intratumor RNA interference of cell cycle genes slows down tumor progression

Gene therapy, 2011-07, Vol.18 (7), p.727-733

2011

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Evaluation of farnesyl:Protein transferase and geranylgeranyl:Protein transferase inhibitor combinations in preclinical models

Cancer research (Chicago, Ill.), 2001-12, Vol.61 (24), p.8758-8768

2001

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Amino-Terminal Basic Residues of Src Mediate Membrane Binding Through Electrostatic Interaction with Acidic Phospholipids

Proceedings of the National Academy of Sciences - PNAS, 1994-12, Vol.91 (25), p.12253-12257

1994

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Ultracentrifugation technique for measuring the binding of peptides and proteins to sucrose-loaded phospholipid vesicles

Methods in molecular biology (Clifton, N.J.), 1998, Vol.84, p.267

1998

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Electrostatics and the Membrane Association of Src: Theory and Experiment

Biochemistry (Easton), 1998-02, Vol.37 (8), p.2145-2159

1998

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Electron-transfer reactions in manganese-depleted photosystem II

Biochemistry (Easton), 1990-09, Vol.29 (38), p.8977-8985

1990

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Myristoylated Alanine-rich C Kinase Substrate (MARCKS) Produces Reversible Inhibition of Phospholipase C by Sequestering Phosphatidylinositol 4,5-Bisphosphate in Lateral Domains

The Journal of biological chemistry, 1996-10, Vol.271 (42), p.26187-26193

1996

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Membrane Binding of Myristylated Peptides Corresponding to the NH2 Terminus of Src

Biochemistry (Easton), 1994-11, Vol.33 (44), p.13093-13101

1994

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Photooxidation of cytochrome b559 in oxygen-evolving photosystem II

Biochemistry (Easton), 1992-11, Vol.31 (46), p.11449-11459

1992

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Farnesyl: proteintransferase inhibitors as agents to inhibit tumor growth

BioFactors (Oxford), 1997, Vol.6 (3), p.359-366

1997

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High-Performance Liquid Chromatography/Mass Spectrometry Characterization of Ki4B-Ras in PSN-1 Cells Treated with the Prenyltransferase Inhibitor L-778,123

Analytical biochemistry, 2001-03, Vol.290 (1), p.126-137

2001

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Anions Modulate the Potency of Geranylgeranyl-Protein Transferase I Inhibitors

The Journal of biological chemistry, 2001-07, Vol.276 (27), p.24457-24465

2001

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Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Journal of molecular biology, 2004-01, Vol.335 (2), p.547-554

2004

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Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 Endoribonuclease Activity

Molecular pharmacology, 2015-10, Vol.88 (6)

2015

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Reevaluation of the stoichiometry of cytochrome b559 in photosystem II and thylakoid membranes

Biochemistry (Easton), 1992-11, Vol.31 (46), p.11441-11448

1992

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2-Arylindole-3-acetamides: FPP-Competitive inhibitors of farnesyl protein transferase

Bioorganic & medicinal chemistry letters, 2001-04, Vol.11 (7), p.865-869

2001

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Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (8), p.2041-2045

2005

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Does the binding of clusters of basic residues to acidic lipids induce domain formation in membranes?

Molecular membrane biology, 1995, Vol.12 (1), p.69-75

1995

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Preclinical in vivo evaluation of a novel treatment strategy combining a Wee1 inhibitor with radiotherapy

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.10596-10596

2010

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Characterization of the multiple forms of cytochrome b559 in photosystem II

Biochemistry (Easton), 1989-10, Vol.28 (20), p.8048-8056

1989

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Contributions of the kinase cross-reactivity profile of MK-0457 to clinical activity

Journal of clinical oncology, 2007-06, Vol.25 (18_suppl), p.7050-7050

2007

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Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3175-3179

2006

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Methyl reorientation in solid 3-ethylchrysene and 3-isopropylchrysene

Solid state nuclear magnetic resonance, 1998-10, Vol.12 (4), p.251-256

1998

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Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.1775-1779

2006

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Kinesin spindle protein (KSP) inhibitors. Part 3: Synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (7), p.1780-1783

2006

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Intratumor RNA interference of cell cycle genes slows down tumor progression

Evaluation of farnesyl:Protein transferase and geranylgeranyl:Protein transferase inhibitor combinations in preclinical models

Amino-Terminal Basic Residues of Src Mediate Membrane Binding Through Electrostatic Interaction with Acidic Phospholipids

Ultracentrifugation technique for measuring the binding of peptides and proteins to sucrose-loaded phospholipid vesicles

Electrostatics and the Membrane Association of Src: Theory and Experiment

Electron-transfer reactions in manganese-depleted photosystem II

Myristoylated Alanine-rich C Kinase Substrate (MARCKS) Produces Reversible Inhibition of Phospholipase C by Sequestering Phosphatidylinositol 4,5-Bisphosphate in Lateral Domains

Membrane Binding of Myristylated Peptides Corresponding to the NH2 Terminus of Src

Photooxidation of cytochrome b559 in oxygen-evolving photosystem II

Farnesyl: proteintransferase inhibitors as agents to inhibit tumor growth

High-Performance Liquid Chromatography/Mass Spectrometry Characterization of Ki4B-Ras in PSN-1 Cells Treated with the Prenyltransferase Inhibitor L-778,123

Anions Modulate the Potency of Geranylgeranyl-Protein Transferase I Inhibitors

Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences

Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 Endoribonuclease Activity

Reevaluation of the stoichiometry of cytochrome b559 in photosystem II and thylakoid membranes

2-Arylindole-3-acetamides: FPP-Competitive inhibitors of farnesyl protein transferase

Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP

Does the binding of clusters of basic residues to acidic lipids induce domain formation in membranes?

Preclinical in vivo evaluation of a novel treatment strategy combining a Wee1 inhibitor with radiotherapy

Characterization of the multiple forms of cytochrome b559 in photosystem II

Contributions of the kinase cross-reactivity profile of MK-0457 to clinical activity

Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP

Methyl reorientation in solid 3-ethylchrysene and 3-isopropylchrysene

Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP

Kinesin spindle protein (KSP) inhibitors. Part 3: Synthesis and evaluation of phenolic 2,4-diaryl-2,5-dihydropyrroles with reduced hERG binding and employment of a phosphate prodrug strategy for aqueous solubility

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