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Interplay of Guanine Oxidation and G‑Quadruplex Folding in Gene Promoters

Journal of the American Chemical Society, 2020-01, Vol.142 (3), p.1115-1136

2020

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On the irrelevancy of hydroxyl radical to DNA damage from oxidative stress and implications for epigenetics

Chemical Society reviews, 2020-09, Vol.49 (18), p.6524-6528

2020

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Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.2604-2609

2017

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Formation and processing of DNA damage substrates for the hNEIL enzymes

Free radical biology & medicine, 2017-06, Vol.107, p.35-52

2017

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Sequencing the Mouse Genome for the Oxidatively Modified Base 8‑Oxo-7,8-dihydroguanine by OG-Seq

Journal of the American Chemical Society, 2017-02, Vol.139 (7), p.2569-2572

2017

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Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (14), p.6784-6789

2019

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8‑Oxo-7,8-dihydroguanine in the Context of a Gene Promoter G‑Quadruplex Is an On–Off Switch for Transcription

ACS chemical biology, 2017-09, Vol.12 (9), p.2417-2426

2017

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Holy Grails in Chemistry, Part II

Accounts of chemical research, 2017-03, Vol.50 (3), p.445-445

Burrows, Cynthia J

2017

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Identification of DNA lesions using a third base pair for amplification and nanopore sequencing

Nature communications, 2015-11, Vol.6 (1), p.8807-8807, Article 8807

2015

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Effect of Oxidative Damage on Charge and Spin Transport in DNA

Journal of the American Chemical Society, 2019-01, Vol.141 (1), p.123-126

2019

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5‑Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8‑oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X‑ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts

Journal of organic chemistry, 2015-07, Vol.80 (14), p.6996-7007

2015

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Nanopore Detection of 8‑Oxoguanine in the Human Telomere Repeat Sequence

ACS nano, 2015-04, Vol.9 (4), p.4296-4307

2015

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Unusual Isothermal Hysteresis in DNA i-Motif pH Transitions: A Study of the RAD17 Promoter Sequence

Biophysical journal, 2018-04, Vol.114 (8), p.1804-1815

2018

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Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps

Journal of the American Chemical Society, 2016-01, Vol.138 (2), p.491-494

2016

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Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8‑Oxo-7,8-dihydroguanine and A and G opposite 5‑Guanidinohydantoin and Spiroiminodihydantoin Diastereomers

Biochemistry (Easton), 2017-09, Vol.56 (38), p.5053-5064

2017

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Crown ether–electrolyte interactions permit nanopore detection of individual DNA abasic sites in single molecules

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (29), p.11504-11509

2012

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Computational Study of Oxidation of Guanine by Singlet Oxygen (1Δg) and Formation of Guanine:Lysine Cross‐Links

Chemistry : a European journal, 2017-04, Vol.23 (24), p.5804-5813

2017

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Single-molecule investigation of G-quadruplex folds of the human telomere sequence in a protein nanocavity

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (40), p.14325-14331

2014

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Collateral Damage Occurs When Using Photosensitizer Probes to Detect or Modulate Nucleic Acid Modifications

Angewandte Chemie International Edition, 2022-02, Vol.61 (7), p.e202110649-n/a

International ed. in English, 2022

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Chemical Modification of siRNA Bases To Probe and Enhance RNA Interference

Journal of organic chemistry, 2011-09, Vol.76 (18), p.7295-7300

2011

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Nanopore Dwell Time Analysis Permits Sequencing and Conformational Assignment of Pseudouridine in SARS-CoV‑2

ACS central science, 2021-10, Vol.7 (10), p.1707-1717

2021

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Superior Removal of Hydantoin Lesions Relative to Other Oxidized Bases by the Human DNA Glycosylase hNEIL1

Biochemistry (Easton), 2008-07, Vol.47 (27), p.7137-7146

2008

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Dynamics of a DNA Mismatch Site Held in Confinement Discriminate Epigenetic Modifications of Cytosine

Journal of the American Chemical Society, 2017-02, Vol.139 (7), p.2750-2756

2017

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mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (11), p.4925-4930

2010

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Efficient UV-induced charge separation and recombination in an 8-oxoguanine-containing dinucleotide

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (32), p.11612-11617

2014

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Interplay of Guanine Oxidation and G‑Quadruplex Folding in Gene Promoters

On the irrelevancy of hydroxyl radical to DNA damage from oxidative stress and implications for epigenetics

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

Formation and processing of DNA damage substrates for the hNEIL enzymes

Sequencing the Mouse Genome for the Oxidatively Modified Base 8‑Oxo-7,8-dihydroguanine by OG-Seq

Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution

8‑Oxo-7,8-dihydroguanine in the Context of a Gene Promoter G‑Quadruplex Is an On–Off Switch for Transcription

Holy Grails in Chemistry, Part II

Identification of DNA lesions using a third base pair for amplification and nanopore sequencing

Effect of Oxidative Damage on Charge and Spin Transport in DNA

5‑Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8‑oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X‑ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts

Nanopore Detection of 8‑Oxoguanine in the Human Telomere Repeat Sequence

Unusual Isothermal Hysteresis in DNA i-Motif pH Transitions: A Study of the RAD17 Promoter Sequence

Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps

Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8‑Oxo-7,8-dihydroguanine and A and G opposite 5‑Guanidinohydantoin and Spiroiminodihydantoin Diastereomers

Crown ether–electrolyte interactions permit nanopore detection of individual DNA abasic sites in single molecules

Computational Study of Oxidation of Guanine by Singlet Oxygen (1Δg) and Formation of Guanine:Lysine Cross‐Links

Single-molecule investigation of G-quadruplex folds of the human telomere sequence in a protein nanocavity

Collateral Damage Occurs When Using Photosensitizer Probes to Detect or Modulate Nucleic Acid Modifications

Chemical Modification of siRNA Bases To Probe and Enhance RNA Interference

Nanopore Dwell Time Analysis Permits Sequencing and Conformational Assignment of Pseudouridine in SARS-CoV‑2

Superior Removal of Hydantoin Lesions Relative to Other Oxidized Bases by the Human DNA Glycosylase hNEIL1

Dynamics of a DNA Mismatch Site Held in Confinement Discriminate Epigenetic Modifications of Cytosine

mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo

Efficient UV-induced charge separation and recombination in an 8-oxoguanine-containing dinucleotide

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